Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 242 time(s) and present in 229 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
PNGPapua New Guinea Karimui Plateau Pawaia0.281080See
RUSRussia Murmansk Saomi Mixed0.240070See
USAUSA Hawaii Okinawa0.2190106See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.209057See
PNGPapua New Guinea East New Britain Rabaul0.161060See
TWNTaiwan Siraya29.40.157051See
AUSAustralia Groote Eylandt Aborigine0.151075See
USAUSA NMDP Japanese0.148524582See
JPNJapan Kyoto and Osaka0.1360165See
RUSRussia Sakhalin Island Nivkhi0.132053See
JPNJapan pop 160.130518604See
JPNJapan pop 30.13001018See
TWNTaiwan Rukai24.00.130050See
JPNJapan pop 10.1290560See
AUSAustralia Kimberly Aborigine0.125041See
KORSouth Korea pop 30.1230485See
JPNJapan Central0.1210371See
USAUSA NMDP Korean0.119577584See
KORSouth Korea pop 10.1060324See
TWNTaiwan Taroko18.20.100055See
TWNTaiwan Paiwan19.60.098051See
TWNTaiwan Tsou19.60.098051See
RUSRussia Tuva pop 20.0950169See
JPNJapan Hyogo15.60.094032See
CHNChina North Han pop 20.0882567See
SCOScotland Orkney16.40.088099See
TWNTaiwan Atayal17.00.0850106See
BRABrazil Terena16.00.085060See
TWNTaiwan Pazeh16.40.082055See
TWNTaiwan Tao16.00.080050See
INDIndia Mumbai Maratha0.080091See
NLDNetherlands UMCU15.60.078164See
JPNJapan pop 50.0780117See
RUSRussia Transbaikal Territory Buryats15.00.0770150See
DEUGermany DKMS - China minority0.07571282See
INDIndia Tamil Nadu Nadar0.074061See
MYSMalaysia Peninsular Chinese12.40.0722194See
USAUSA Caucasian pop 20.0720265See
USAUSA Philadelphia Caucasian14.30.0710141See
ESPSpain Gipuzkoa Basque0.0710100See
BRABrazil Puyanawa13.30.0700150See
RUSRussia Arkhangelsk Pomor0.070063See
CHNChina Shanxi HIV negative0.068022See
CHNChina Beijing0.068067See
ENGEngland North West12.80.0640298See
FRAFrance Southeast12.30.0640130See
CHNChina Han HIV negative0.063072See
CHNChina Wuhan12.50.0630121See
CHNChina Henan HIV negative0.063016See
TURTurkey pop 50.0630142See
CHESwitzerland Sion0.0627832See
CHESwitzerland Bern0.06203545See
DEUGermany pop 60.06188862See
CHESwitzerland Basel0.06171888See
PRTPortugal Azores Terceira Island12.30.0614130See
USAUSA Caucasian Bethesda12.10.0610307See
TWNTaiwan Puyuma12.00.060050See
MEXMexico Oaxaca Zapotec0.060090See
DEUGermany DKMS - Netherlands minority0.05941374See
ZAFSouth Africa Caucasians0.0590102See
DEUGermany DKMS - United Kingdom minority0.05901043See
CHNChina Marrow Donor Registry0.0580600See
NLDNetherlands Leiden0.05801305See
DEUGermany DKMS - Austria minority0.05791698See
CHNChina Yunnan Hani0.0570150See
FRAFrance West11.00.0566100See
CHESwitzerland St Gallen0.05622113See
CHESwitzerland Geneva0.056080See
CHNChina South Han pop 20.05511098See
AUSAustralia Yuendumu Aborigine0.0550191See
AUSAustralia New South Wales Caucasian0.0550134See
ITAItaly Bergamo10.90.0550101See
USAUSA Eastern European0.0550558See
PRTAzores Terceira Island0.0550130See
TWNTaiwan Minnan pop 19.80.0540102See
TWNTaiwan Bunun10.90.0540101See
USAUSA NMDP European Caucasian0.05341242890See
USAUSA San Antonio Caucasian0.0515222See
DEUGermany pop 80.051139689See
ESPSpain Andalusia Romani0.051099See
CHESwitzerland Lausanne0.0510993See
CHESwitzerland Geneva pop 20.05071267See
USAUSA Asian pop 20.05021772See
VNMVietnam Hanoi Kinh pop 20.0500170See
CHNChina Yunnan Province Han0.0500101See
PHLPhilippines Ivatan10.00.050050See
NIRIreland Northern9.90.05001000See
PNGPapua New Guinea Wanigela Keapara0.049066See
DEUGermany Essen9.20.0490174See
CHESwitzerland Zurich0.04824875See
RUSRussia Bering Island Aleuts0.0481104See
RUSRussia Nenet Mixed0.048055See
USAUSA San Diego9.60.0480496See
CZECzech Republic NMDR0.04745099See
USAUSA NMDP Chinese0.047399672See
GBRUnited Kingdom pop 38.90.0470604See
GEOGeorgia Tibilisi0.0470109See
CHESwitzerland Aargau-Solothurn0.04701838See
BRABrazil Mixed0.0470108See
RUSRussia Karelia0.04701075See
CHESwitzerland Graubunden0.0469759See
ESPSpain Catalonia Girona0.046088See
USAUSA San Francisco Caucasian0.0460220See
USAUSA Caucasian pop 40.04581070See
DEUGermany DKMS - Romania minority0.04541234See
DEUGermany DKMS - France minority0.04531406See
DEUGermany DKMS - Spain minority0.04521107See
FRAFrance Corsica Island0.0450100See
USAUSA NMDP American Indian South or Central America0.04405926See
USAUSA NMDP Alaska Native or Aleut0.04401376See
ESPSpain Andalusia0.043099See
TWNTaiwan Han Chinese0.0420504See
ZAFSouth Africa Natal Tamil0.042051See
USAUSA NMDP North American Amerindian0.041735791See
POLPoland DKMS0.041620653See
TWNTaiwan Ami8.20.041098See
CHNChina South Han0.0410284See
IRLIreland South8.00.0400250See
MEXMexico Oaxaca Mixtec0.0400103See
USAUSA Asian0.0400358See
USAUSA NMDP Vietnamese0.039743540See
DEUGermany DKMS - Portugal minority0.03851176See
COLColombia North Wiwa El Encanto0.038552See
CZECzech Republic0.0380106See
CHNChina Canton Han0.0380264See
MEXMexico Oaxaca Mixe0.038055See
HKGHong Kong Chinese BMDR0.03717595See
DEUGermany DKMS - Croatia minority0.03702057See
UGAUganda Kampala0.0370161See
SGPSingapore SGVP Chinese CHS0.037096See
USAUSA NMDP Mexican or Chicano0.0366261235See
DEUGermany DKMS - Greece minority0.03641894See
TWNTaiwan Hakka7.30.036055See
USAUSA North American Native0.0350187See
ITAItaly pop 50.0350975See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,6.90.03484335See
NICNicaragua Managua7.00.0348339See
CHESwitzerland Lugano0.03401169See
USAUSA Hispanic pop 20.03401999See
DEUGermany DKMS - Italy minority0.03301159See
ESPSpain Majorca and Minorca0.033090See
NCLNew Caledonia0.033065See
DEUGermany DKMS - Bosnia and Herzegovina minority0.03261028See
CHNChina Southwest Dai0.0320124See
USAUSA South Texas Hispanic0.0300194See
TWNTaiwan pop 20.0300364See
MEXMexico Mexico City Mestizo pop 20.0299234See
USAUSA NMDP Hispanic South or Central American0.0298146714See
USAUSA NMDP Caribean Hispanic0.0292115374See
LKASri Lanka Colombo5.60.0290714See
CHNChina Sichuan HIV negative0.029034See
USAUSA NMDP Middle Eastern or North Coast of Africa0.028970890See
AUSAustralia Cape York Peninsula Aborigine0.0280103See
USAUSA NMDP Filipino0.027350614See
CHESwitzerland Luzern0.02721553See
GRCGreece pop 60.0269242See
CHNChina Uyghur HIV negative0.026019See
USAUSA Hispanic0.0260234See
USAUSA NMDP Caribean Indian0.025014339See
ITAItaly North Pavia0.025081See
ITAItaly South0.0250141See
USAUSA NMDP Hawaiian or other Pacific Islander0.024011499See
USAUSA Arizona Gila River Amerindian0.0240492See
NZLNew Zealand Polynesians with Full Ancestry4.80.024021See
NZLNew Zealand Maori with Admixed History4.80.0240105See
CHLChile Easter Island0.024021See
MEXMexico Chihuahua Tarahumara0.023044See
ITAItaly North0.0230277See
DEUGermany DKMS - Turkey minority0.02254856See
ZMBZambia Lusaka0.022044See
ESPSpain Sevilla4.30.0216278See
JORJordan Amman0.0210146See
USAUSA NMDP Southeast Asian0.020327978See
THAThailand Northeast0.020066See
ITAItaly Sardinia pop30.0200100See
ASMAmerican Samoa0.020051See
NZLNew Zealand Polynesians with Admixed History3.70.019027See
SGPSingapore SGVP. Indian INS0.019086See
ZAFSouth Africa Worcester4.00.0190159See
GRCGreece pop 83.60.018183See
PNGPapua New Guinea Wosera Abelam0.0180131See
THAThailand Northeast pop 20.0180400See
USAUSA African American0.0180252See
COLColombia Bogotá Cord Blood3.60.01781463See
GEOGeorgia Tibilisi Kurd0.017031See
CHNChina Yunnan Bulang0.0170116See
SGPSingapore SGVP Malay MAS0.017089See
MYSMalaysia Peninsular Indian3.00.0166271See
PNGPapua New Guinea West Schrader Ranges Haruai0.016055See
RUSRussia North Ossetian2.40.0157127See
INDIndia Tamil Nadu0.01552492See
USAUSA NMDP South Asian Indian0.0152185391See
LBNLebanon Mixed0.015097See
PAKPakistan Baloch0.015066See
PAKPakistan Mixed Pathan0.0150100See
PAKPakistan Kalash0.014069See
ENGEngland London Ashkenazi Jews0.0140500See
SGPSingapore Riau Malay0.0140132See
IRNIran Tehran0.0130120See
USAUSA NMDP African American pop 20.0129416581See
MYSMalaysia Peninsular Malay2.30.0121951See
MLIMali Bandiagara0.0120138See
USAUSA NMDP Caribean Black0.011833328See
USAUSA African American pop 40.01182411See
MEXMexico Chiapas Lacandon Mayans0.0115218See
USAUSA African American Bethesda2.10.0110187See
PRTPortugal Center pop 20.0110562See
TWNTaiwan Saisiat2.00.010051See
PERPeru Arequipa Mestizo2.00.0100168See
PAKPakistan Mixed Sindhi0.0100101See
CHNChina Guangzhou0.0100102See
BFABurkina Faso Fulani0.010049See
USAUSA NMDP African0.009128557See
ZWEZimbabwe Harare Shona0.0090230See
IRNIran Gorgan0.007864See
GHAGhana Ga-Adangbe1.50.0076131See
INDIndia Delhi pop 21.20.006090See
PAKPakistan Karachi Parsi0.005091See
GNQEquatorial Guinea Bioko Island Bubi0.0050100See
SGPSingapore Thai0.0050100See
SAUSaudi Arabia Guraiat and Hail1.00.0050213See
SDNSudan Mixed1.00.0050200See
KENKenya Luo0.0020265See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
KENKenya Nandi0.0000240See
INDIndia West Coast Parsi0.000050See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
PAKPakistan Brahui0.0000104See
PNGPapua New Guinea Madang0.000065See
BFABurkina Faso Mossi0.000053See
BFABurkina Faso Rimaibe0.000047See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CHNChina North Han0.0000105See
SENSenegal Niokholo Mandenka0.0000165See
TWNTaiwan Thao0.00.000030See

See also higher resolution data of this allele

Allele  Number of Populations 
 C*03:03:01 45 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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