Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 204 time(s) and present in 163 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
COLColombia Arhuaco NA-DHS_16 (G)11.80.058817See
AREUnited Arab Emirates Abu Dhabi0.057752See
PAKPakistan Mixed Pathan0.0550100See
IRNIran Tehran0.0490120See
GEOGeorgia Tibilisi0.0420109See
RUSRussia North Ossetian7.90.0394127See
SDNSudan East Rashaida7.40.037727See
ESPSpain Andalusia0.037099See
GRCGreece pop 87.20.036183See
COLColombia Kogi NA-DHS_17 (G)7.10.035715See
AREUnited Arab Emirates Pop 10.0320570See
MYSMalaysia Peninsular Indian6.30.0314271See
ZAFSouth Africa Natal Tamil0.031051See
PAKPakistan Kalash0.029069See
USAUSA NMDP South Asian Indian0.0279185391See
CANCanada Cree NA-DHS_3 (G)5.60.027818See
INDIndia South UCBB5.20.026211446See
IRNIran Baloch0.0260100See
CHNChina Uyghur HIV negative0.026019See
ESPSpain Andalusia Romani0.026099See
INDIndia Tamil Nadu0.02572492See
INDIndia Delhi pop 24.90.025090See
SDNSudan Mixed5.00.0250200See
INDIndia North UCBB4.70.02365849See
DEUGermany DKMS - Turkey minority0.02344856See
IRNIran Gorgan0.023464See
ITAItaly North0.0230277See
DEUGermany DKMS - Greece minority0.02301894See
INDIndia Central UCBB4.30.02144204See
INDIndia East UCBB4.20.02122403See
INDIndia West UCBB4.20.02105829See
JORJordan Amman0.0210146See
LBNLebanon Mixed0.021097See
ITAItaly pop 50.0200975See
PAKPakistan Burusho0.020092See
TTOTrinidad South Asian0.020087See
USAUSA NMDP Southeast Asian0.019227978See
PAKPakistan Mixed Sindhi0.0190101See
LKASri Lanka Colombo3.60.0190714See
SGPSingapore SGVP. Indian INS0.019086See
USAUSA NMDP Caribean Indian0.018014339See
GEOGeorgia Tibilisi Kurd0.017031See
MARMorocco Nador Metalsa pop 20.016073See
USAUSA NMDP Middle Eastern or North Coast of Africa0.015770890See
CHESwitzerland Geneva pop 20.01561267See
DEUGermany DKMS - Portugal minority0.01531176See
USAUSA NMDP Caribean Hispanic0.0151115374See
INDIndia North pop 20.015072See
ISRIsrael Arab Druze0.0150101See
CHESwitzerland Lausanne0.0146993See
DEUGermany DKMS - Italy minority0.01401159See
CHNChina Qinghai Province Hui0.0140110See
KENKenya Nandi0.0130240See
CHESwitzerland Geneva0.013080See
SAUSaudi Arabia Guraiat and Hail2.40.0120213See
PRTPortugal Center pop 20.0110562See
ESPSpain Majorca and Minorca0.011090See
ITAItaly Bergamo2.00.0110101See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0110146See
TURTurkey pop 50.0110142See
GRCGreece pop 60.0103242See
DEUGermany DKMS - Spain minority0.01021107See
FRAFrance Corsica Island0.0100100See
AUSAustralia New South Wales Caucasian0.0100134See
ZAFSouth Africa Caucasians0.0100102See
CHESwitzerland Graubunden0.0099759See
USAUSA Spain Ancestry0.0090279See
USAUSA Italy Ancestry0.0090273See
ESPSpain Sevilla1.80.0090278See
PRTPortugal Azores Terceira Island1.80.0088130See
INDIndia Northeast UCBB1.70.0085296See
CHESwitzerland Zurich0.00824875See
USAUSA Caucasian Bethesda1.50.0080307See
FRAFrance Southeast1.50.0080130See
PRTAzores Terceira Island0.0080130See
PAKPakistan Baloch0.008066See
USAUSA Asian pop 20.00791772See
DEUGermany DKMS - Croatia minority0.00782057See
CHESwitzerland St Gallen0.00762113See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,1.50.00754335See
CHESwitzerland Sion0.0074832See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00731028See
MARMorocco Atlantic Coast Chaouya0.007098See
MARMorocco Settat Chaouya1.40.007098See
COLColombia Bogotá Cord Blood1.40.00681463See
DEUGermany DKMS - France minority0.00661406See
CHESwitzerland Lugano0.00661169See
CZECzech Republic NMDR0.00655099See
DEUGermany DKMS - Romania minority0.00651234See
DEUGermany DKMS - Austria minority0.00621698See
DEUGermany pop 80.006039689See
KENKenya Luo0.0060265See
ESPSpain Catalonia Girona0.006088See
CHESwitzerland Bern0.00563545See
USAUSA Hispanic pop 20.00551999See
MYSMalaysia Peninsular Malay1.10.0053951See
MYSMalaysia Peninsular Chinese1.00.0052194See
PAKPakistan Brahui0.0050104See
TWNTaiwan Minnan pop 11.00.0050102See
ITAItaly Sardinia pop30.0050100See
BRABrazil Mixed0.0050108See
USAUSA Mexican American Mestizo0.0050553See
USAUSA South Dakota Lakota Sioux0.0050302See
RUSRussia Bering Island Aleuts0.0048104See
USAUSA Caucasian pop 40.00471070See
POLPoland DKMS0.004320653See
DEUGermany DKMS - German donors0.00403456066See
ITAItaly South0.0040141See
IRLIreland South0.80.0040250See
USAUSA Eastern European0.0040558See
USAUSA South Texas Hispanic0.0040194See
USAUSA Caucasian pop 20.0040265See
USAUSA Hispanic0.0040234See
USAUSA NMDP Hispanic South or Central American0.0039146714See
CHESwitzerland Basel0.00391888See
USAUSA NMDP Mexican or Chicano0.0038261235See
MEXMexico Mexico City Mestizo population0.0035143See
DEUGermany pop 60.00338862See
USAUSA NMDP African0.003228557See
USAUSA NMDP American Indian South or Central America0.00305926See
UGAUganda Kampala0.0030161See
UGAUganda Kampala pop 20.0030175See
USAUSA Asian0.0030358See
USAUSA San Diego0.60.0030496See
ENGEngland North West0.70.0030298See
ENGEngland London Ashkenazi Jews0.0030500See
KORSouth Korea pop 10.0030324See
RUSRussia Transbaikal Territory Buryats1.00.0030150See
RUSRussia Karelia0.00281075See
USAUSA NMDP European Caucasian0.00271242890See
CHESwitzerland Aargau-Solothurn0.00231838See
MEXMexico Mexico City Mestizo pop 20.0021234See
NLDNetherlands Leiden0.00201305See
CHNChina Marrow Donor Registry0.0020600See
USAUSA San Francisco Caucasian0.0020220See
THAThailand Northeast0.002066See
GBRUnited Kingdom pop 30.30.0020604See
USAUSA NMDP Hawaiian or other Pacific Islander0.002011499See
DEUGermany DKMS - United Kingdom minority0.00191043See
DEUGermany DKMS - China minority0.00181282See
TZATanzania Maasai0.30.0016336See
CHNChina Hubei Han0.30.00153732See
USAUSA NMDP Vietnamese0.001443540See
THAThailand Northeast pop 20.0010400See
NIRIreland Northern0.10.00101000See
USAUSA NMDP North American Amerindian0.001035791See
CHNChina South Han pop 20.00091098See
HKGHong Kong Chinese BMDR0.00097595See
USAUSA NMDP Caribean Black0.000733328See
DEUGermany DKMS - Netherlands minority0.00071374See
USAUSA NMDP Chinese0.000799672See
USAUSA African American pop 40.00042411See
USAUSA NMDP Filipino0.000250614See
USAUSA NMDP African American pop 20.0002416581See
USAUSA NMDP Japanese0.000124582See
USAUSA NMDP Korean0.000177584See
USAUSA Alaska Yupik0.0000252See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA San Antonio Caucasian0.0000222See
USAUSA African American Bethesda0.00.0000187See
ZMBZambia Lusaka0.000044See
USAUSA North American Native0.0000187See
USAUSA African American0.0000252See
CHESwitzerland Luzern0.00001553See
ITAItaly North pop 30.00.000097See
KORSouth Korea pop 30.0000485See
CHNChina North Han pop 20.0000567See
AUSAustralia Yuendumu Aborigine0.0000191See
CHNChina North Han0.0000105See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina Inner Mongolia Region0.0000102See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
BFABurkina Faso Fulani0.000049See
BFABurkina Faso Mossi0.000053See
BFABurkina Faso Rimaibe0.000047See
FRAFrance West0.00.0000100See
MLIMali Bandiagara0.0000138See
PHLPhilippines Ivatan0.00.000050See
SCOScotland Orkney0.00.000099See
SENSenegal Niokholo Mandenka0.0000165See
SGPSingapore SGVP Chinese CHS0.000096See
ESPSpain Gipuzkoa Basque0.0000100See
SGPSingapore SGVP Malay MAS0.000089See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Han Chinese0.0000504See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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