Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 205 time(s) and present in 184 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
JPNJapan Kyoto and Osaka0.1000165See
CHNChina Guizhou Province Miao pop 20.094085See
USAUSA NMDP Korean0.082377584See
INDIndia New Delhi0.080071See
USAUSA NMDP Japanese0.078124582See
CHNChina Yunnan Province Han0.0740101See
USAUSA Hawaii Okinawa0.0710106See
MYSMalaysia Peninsular Indian12.90.0701271See
JPNJapan pop 160.068718604See
JPNJapan pop 10.0670560See
JPNJapan pop 30.06501018See
KORSouth Korea pop 30.0650485See
INDIndia Tamil Nadu0.05772492See
JPNJapan pop 50.0570117See
CHNChina Southwest Dai0.0560124See
CHNChina Uyghur HIV negative0.053019See
USAUSA Asian0.0500358See
JPNJapan Central0.0490371See
ITAItaly North0.0490277See
SGPSingapore SGVP Chinese CHS0.048096See
USAUSA Asian pop 20.04801772See
SGPSingapore Riau Malay0.0470132See
GEOGeorgia Tibilisi0.0470109See
INDIndia South UCBB9.40.047011446See
CHNChina North Han pop 20.0467567See
CHESwitzerland Lugano0.04591169See
MYSMalaysia Peninsular Malay8.80.0452951See
MKDMacedonia pop 40.0440216See
CHNChina Marrow Donor Registry0.0440600See
GRCGreece pop 88.40.042283See
CHNChina Hubei Han8.40.04183732See
CHNChina Guangzhou0.0410102See
ITAItaly pop 50.0410975See
USAUSA NMDP Chinese0.040699672See
DEUGermany DKMS - Bosnia and Herzegovina minority0.03941028See
RUSRussia North Ossetian7.90.0394127See
GRCGreece pop 60.0393242See
CMRCameroon Bamileke0.039077See
CHNChina Yunnan Bulang0.0390116See
LKASri Lanka Colombo7.40.0390714See
CHNChina South Han pop 20.03831098See
CHESwitzerland Geneva0.038080See
USAUSA NMDP Southeast Asian0.037327978See
SGPSingapore SGVP. Indian INS0.037086See
DEUGermany DKMS - Turkey minority0.03664856See
CHNChina South Han0.0360284See
TWNTaiwan Hakka7.30.036055See
HKGHong Kong Chinese BMDR0.03587595See
FRAFrance West7.00.0356100See
TWNTaiwan pop 20.0350364See
DEUGermany DKMS - China minority0.03371282See
USAUSA NMDP South Asian Indian0.0336185391See
TWNTaiwan Han Chinese0.0330504See
IRNIran Tehran0.0330120See
CHNChina Canton Han0.0320264See
IRNIran Gorgan0.031364See
CHNChina Sichuan HIV negative0.029034See
TWNTaiwan Minnan pop 15.90.0290102See
USAUSA NMDP Caribean Indian0.029014339See
CHESwitzerland Graubunden0.0287759See
SGPSingapore SGVP Malay MAS0.028089See
MEXMexico Mexico City Mestizo population0.0280143See
INDIndia West UCBB5.50.02775829See
DEUGermany DKMS - Greece minority0.02751894See
INDIndia North UCBB5.40.02725849See
SGPSingapore Thai0.0270100See
PRTAzores Terceira Island0.0270130See
PRTPortugal Azores Terceira Island5.30.0263130See
SAUSaudi Arabia Guraiat and Hail5.20.0260213See
VNMVietnam Hanoi Kinh pop 20.0260170See
MYSMalaysia Peninsular Chinese5.20.0258194See
ITAItaly South0.0250141See
USAUSA NMDP Caribean Hispanic0.0246115374See
BRABrazil Mixed0.0240108See
CHESwitzerland Luzern0.02401553See
USAUSA NMDP Middle Eastern or North Coast of Africa0.023670890See
INDIndia Central UCBB4.60.02324204See
INDIndia East UCBB4.60.02312403See
CHNChina Beijing0.023067See
CHNChina Shanxi HIV negative0.023022See
USAUSA NMDP Vietnamese0.022543540See
CHESwitzerland Aargau-Solothurn0.02231838See
USAUSA San Diego4.50.0220496See
CHESwitzerland Basel0.02131888See
USAUSA Caucasian pop 20.0210265See
ZAFSouth Africa Natal Tamil0.021051See
CHESwitzerland Zurich0.02094875See
DEUGermany DKMS - Portugal minority0.02081176See
DEUGermany DKMS - Croatia minority0.02072057See
CHESwitzerland St Gallen0.02062113See
RUSRussia Transbaikal Territory Buryats4.00.0200150See
USAUSA African American0.0200252See
TWNTaiwan Saisiat3.90.020051See
TWNTaiwan Siraya3.90.020051See
AREUnited Arab Emirates Abu Dhabi0.019252See
CHESwitzerland Bern0.01923545See
CHNChina Guizhou Province Shui0.0190153See
FRAFrance Southeast3.80.0190130See
MLIMali Bandiagara0.0190138See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,3.60.01864335See
USAUSA NMDP Caribean Black0.018533328See
CHESwitzerland Lausanne0.0182993See
DEUGermany DKMS - France minority0.01811406See
AREUnited Arab Emirates Pop 10.0180570See
TWNTaiwan Pazeh3.60.018055See
USAUSA Hispanic0.0170234See
BRABrazil Puyanawa3.30.0170150See
GEOGeorgia Tibilisi Kurd0.017031See
DEUGermany DKMS - Italy minority0.01691159See
USAUSA NMDP African American pop 20.0165416581See
DEUGermany DKMS - Spain minority0.01641107See
USAUSA African American Bethesda3.20.0160187See
USAUSA Eastern European0.0160558See
DEUGermany DKMS - Austria minority0.01591698See
NLDNetherlands UMCU3.10.015664See
USAUSA NMDP African0.015528557See
USAUSA NMDP Hispanic South or Central American0.0154146714See
DEUGermany DKMS - Romania minority0.01541234See
GHAGhana Ga-Adangbe3.10.0153131See
DEUGermany pop 80.015239689See
KENKenya, Nyanza Province, Luo tribe3.00.0150100See
UGAUganda Kampala0.0150161See
CHNChina Guizhou Province Bouyei0.0140109See
USAUSA NMDP North American Amerindian0.013535791See
USAUSA NMDP Filipino0.013550614See
DEUGermany DKMS - German donors0.01343456066See
USAUSA Hispanic pop 20.01331999See
USAUSA Caucasian pop 40.01311070See
USAUSA North American Native0.0130187See
SDNSudan Mixed2.00.0130200See
NLDNetherlands Leiden0.01301305See
USAUSA NMDP European Caucasian0.01271242890See
USAUSA African American pop 40.01272411See
DEUGermany pop 60.01228862See
ESPSpain Andalusia0.012099See
INDIndia Delhi pop 22.50.012090See
DEUGermany DKMS - Netherlands minority0.01161374See
CZECzech Republic NMDR0.01115099See
CMRCameroon Beti0.0110174See
GBRUnited Kingdom pop 32.20.0110604See
USAUSA NMDP American Indian South or Central America0.01105926See
ESPSpain Sevilla2.20.0108278See
INDIndia Northeast UCBB2.00.0101296See
KENKenya Nandi0.0100240See
LBNLebanon Mixed0.010097See
SGPSingapore Javaneses0.010051See
CHNChina Yunnan Hani0.0100150See
AUSAustralia New South Wales Caucasian0.0100134See
USAUSA NMDP Alaska Native or Aleut0.01001376See
ZAFSouth Africa Caucasians0.0100102See
USAUSA NMDP Mexican or Chicano0.0095261235See
RUSRussia Karelia0.00931075See
POLPoland DKMS0.009420653See
COLColombia Bogotá Cord Blood1.80.00921463See
RUSRussia Tuva pop 20.0090169See
MEXMexico Oaxaca Mixe0.009055See
USAUSA San Antonio Caucasian0.0090222See
USAUSA San Francisco Caucasian0.0090220See
DEUGermany DKMS - United Kingdom minority0.00861043See
MEXMexico Mexico City Mestizo pop 20.0085234See
USAUSA NMDP Hawaiian or other Pacific Islander0.008511499See
NICNicaragua Managua1.50.0073339See
CHESwitzerland Geneva pop 20.00671267See
ITAItaly North Pavia0.006081See
ZAFSouth Africa Worcester1.00.0060159See
USAUSA Philadelphia Caucasian1.00.0050141See
ISRIsrael Arab Druze0.0050101See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0050146See
NIRIreland Northern0.90.00501000See
CHLChile Santiago Mixed1.00.005070See
IRLIreland South0.80.0040250See
KENKenya Luo0.0040265See
ZWEZimbabwe Harare Shona0.0040230See
CHESwitzerland Sion0.0033832See
TZATanzania Maasai0.60.0031336See
UGAUganda Kampala pop 20.0030175See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
USAUSA Alaska Yupik0.0000252See
ZMBZambia Lusaka0.000044See
USAUSA Caucasian Bethesda0.00.0000307See
AUSAustralia Yuendumu Aborigine0.0000191See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CHNChina North Han0.0000105See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
MEXMexico Oaxaca Mixtec0.0000103See
MEXMexico Oaxaca Zapotec0.000090See
PHLPhilippines Ivatan0.00.000050See
SENSenegal Niokholo Mandenka0.0000165See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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