Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 224 time(s) and present in 187 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
PAKPakistan Karachi Parsi0.132091See
ENGEngland London Ashkenazi Jews0.0970500See
ESPSpain Sevilla17.60.0899278See
CMRCameroon Bakola Pygmy16.00.083450See
CMRCameroon Beti0.0800174See
MEXMexico Oaxaca Mixtec0.0780103See
BRABrazil Mixed0.0750108See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0740146See
CMRCameroon Bamileke0.071077See
PRTPortugal Azores Terceira Island14.00.0702130See
ZMBZambia Lusaka0.067044See
COLColombia Inga NA-DHS_11 (G)13.30.066716See
MARMorocco Settat Chaouya12.80.064098See
MARMorocco Atlantic Coast Chaouya0.064098See
USAUSA African American Bethesda11.70.0640187See
PRTAzores Terceira Island0.0620130See
UGAUganda Kampala0.0610161See
ESPSpain Andalusia0.061099See
USAUSA San Francisco Caucasian0.0580220See
PRTPortugal Center pop 20.0580562See
NIRIreland Northern10.90.05701000See
DEUGermany DKMS - Spain minority0.05691107See
MARMorocco Nador Metalsa pop 20.056073See
LBNLebanon Mixed0.056097See
USAUSA South Texas Hispanic0.0560194See
PRYParaguay/Argentina Guarani NA-DHS_23 (G)11.10.055610See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,10.90.05554335See
USAUSA San Antonio Caucasian0.0545222See
USAUSA NMDP Hispanic South or Central American0.0526146714See
USAUSA Mexican American Mestizo0.0520553See
DEUGermany DKMS - Portugal minority0.05171176See
USAUSA NMDP Mexican or Chicano0.0512261235See
USAUSA Hispanic0.0510234See
FRAFrance Southeast10.00.0510130See
KENKenya Luo0.0510265See
ITAItaly South0.0500141See
CHESwitzerland Geneva pop 20.05001267See
COLColombia Bogotá Cord Blood9.70.04921463See
USAUSA Hispanic pop 20.04931999See
USAUSA Italy Ancestry0.0480273See
IRLIreland South9.60.0480250See
BOLBolivia/Peru Quechua NA-DHS_12 (G)9.50.047621See
NICNicaragua Managua9.20.0476339See
USAUSA NMDP Caribean Hispanic0.0458115374See
BGRBulgaria Romani0.045013See
USAUSA African American pop 30.0430564See
USAUSA Caucasian Bethesda8.30.0420307See
USAUSA NMDP Middle Eastern or North Coast of Africa0.040970890See
MEXMexico Mexico City Mestizo pop 20.0406234See
KENKenya, Nyanza Province, Luo tribe8.00.0400100See
UGAUganda Kampala pop 20.0400175See
USAUSA NMDP European Caucasian0.03851242890See
COLColombia North Wiwa El Encanto0.038552See
USAUSA Caucasian pop 40.03831070See
USAUSA Caucasian pop 20.0380265See
ZWEZimbabwe Harare Shona0.0380230See
CHESwitzerland Geneva0.038080See
IRNIran Tehran0.0380120See
ITAItaly pop 50.0380975See
USAUSA African American pop 40.03732411See
DEUGermany DKMS - Italy minority0.03711159See
GBRUnited Kingdom pop 37.50.0370604See
USAUSA San Diego6.70.0370496See
USAUSA NMDP Caribean Indian0.037014339See
USAUSA NMDP African0.036828557See
CHESwitzerland Lugano0.03671169See
MEXMexico Mexico City Mestizo population0.0350143See
USAUSA NMDP American Indian South or Central America0.03505926See
CHESwitzerland Sion0.0347832See
USAUSA NMDP African American pop 20.0340416581See
DEUGermany DKMS - France minority0.03351406See
RUSRussia Tundra Nentsi NA-DHS_1 (G)6.70.033316See
USAUSA NMDP Caribean Black0.032933328See
USAUSA Spain Ancestry0.0320279See
USAUSA African American0.0320252See
ENGEngland North West6.40.0320298See
CHLChile Huilliche NA-DHS_14 (G)6.30.031220See
CHESwitzerland Graubunden0.0311759See
USAUSA Eastern European0.0310558See
GHAGhana Ga-Adangbe6.10.0305131See
CHLChile Santiago Mixed6.00.030470See
DEUGermany DKMS - Bosnia and Herzegovina minority0.03021028See
AUSAustralia New South Wales Caucasian0.0300134See
DEUGermany DKMS - United Kingdom minority0.02981043See
NZLNew Zealand Maori with Admixed History5.70.0290105See
AREUnited Arab Emirates Abu Dhabi0.028852See
USAUSA NMDP North American Amerindian0.028635791See
SENSenegal Niokholo Mandenka0.0280165See
TURTurkey pop 50.0280142See
CANCanada Cree NA-DHS_3 (G)5.60.027818See
DEUGermany DKMS - Austria minority0.02711698See
IRNIran Baloch0.0260100See
DEUGermany DKMS - Romania minority0.02551234See
CHESwitzerland Luzern0.02541553See
BOLBolivia/Chile Aymara NA-DHS_13 (G)5.00.025020See
SDNSudan Mixed5.00.0250200See
USAUSA NMDP Alaska Native or Aleut0.02501376See
ZAFSouth Africa Caucasians0.0250102See
DEUGermany DKMS - Turkey minority0.02434856See
CHESwitzerland Aargau-Solothurn0.02411838See
CHLChile Easter Island0.024021See
KORSouth Korea pop 30.0240485See
DEUGermany pop 80.023839689See
CHESwitzerland St Gallen0.02372113See
DEUGermany DKMS - German donors0.02313456066See
CHESwitzerland Basel0.02301888See
MLIMali Bandiagara0.0230138See
ITAItaly North0.0220277See
DEUGermany pop 60.02218862See
DEUGermany DKMS - Greece minority0.02191894See
CHESwitzerland Zurich0.02194875See
CHESwitzerland Bern0.02063545See
CZECzech Republic NMDR0.02055099See
TZATanzania Maasai4.10.0203336See
USAUSA Philadelphia Caucasian4.40.0200141See
NLDNetherlands Leiden0.02001305See
DEUGermany DKMS - Croatia minority0.01972057See
RUSRussia Bering Island Aleuts0.0192104See
ZAFSouth Africa Worcester4.00.0190159See
USAUSA North American Native0.0190187See
RUSRussia Karelia0.01891075See
DEUGermany DKMS - Netherlands minority0.01861374See
POLPoland DKMS0.017420653See
GRCGreece pop 60.0165242See
CHESwitzerland Lausanne0.0162993See
NLDNetherlands UMCU3.10.015664See
CAFCentral African Republic Mbenzele Pygmy3.00.015136See
ISRIsrael Arab Druze0.0150101See
GEOGeorgia Tibilisi0.0140109See
CZECzech Republic0.0140106See
SAUSaudi Arabia Guraiat and Hail2.80.0140213See
USAUSA South Dakota Lakota Sioux0.0130302See
AREUnited Arab Emirates Pop 10.0130570See
USAUSA NMDP Korean0.012477584See
USAUSA NMDP Hawaiian or other Pacific Islander0.011911499See
NCLNew Caledonia0.011065See
COLColombia North Chimila Amerindians0.010647See
ASMAmerican Samoa0.010051See
BRABrazil Puyanawa2.00.0100150See
CHNChina North Han0.0100105See
PAKPakistan Brahui0.0100104See
FRAFrance West2.00.0100100See
MEXMexico Chiapas Lacandon Mayans0.0092218See
MEXMexico Oaxaca Mixe0.009055See
DEUGermany Essen1.70.0090174See
CHNChina Beijing0.008067See
MEXMexico Tixcacaltuyub Maya0.007567See
CHNChina North Han pop 20.0071567See
AUSAustralia Groote Eylandt Aborigine0.007075See
MEXMexico Oaxaca Zapotec0.007090See
GRCGreece pop 81.20.006083See
KENKenya Nandi0.0060240See
SGPSingapore SGVP. Indian INS0.006086See
DEUGermany DKMS - China minority0.00531282See
CHNChina Qinghai Province Hui0.0050110See
RUSRussia North Ossetian0.80.0039127See
USAUSA Asian pop 20.00401772See
USAUSA NMDP Filipino0.003950614See
USAUSA NMDP Southeast Asian0.003027978See
USAUSA Arizona Gila River Amerindian0.0030492See
RUSRussia Transbaikal Territory Buryats1.00.0030150See
CHNChina Hubei Han0.50.00233732See
CHNChina Canton Han0.0020264See
CHNChina South Han0.0020284See
USAUSA NMDP South Asian Indian0.0019185391See
USAUSA NMDP Japanese0.001924582See
CHNChina South Han pop 20.00181098See
USAUSA NMDP Chinese0.001299672See
INDIndia West UCBB0.20.00125829See
INDIndia Tamil Nadu0.00102492See
LKASri Lanka Colombo0.30.0010714See
CHNChina Marrow Donor Registry0.0010600See
USAUSA Asian0.0010358See
INDIndia North UCBB0.20.00095849See
INDIndia South UCBB0.20.000711446See
INDIndia Central UCBB0.10.00074204See
RUSRussia Nizhny Novgorod, Russians0.10.00071510See
USAUSA NMDP Vietnamese0.000643540See
HKGHong Kong Chinese BMDR0.00057595See
JPNJapan pop 160.000318604See
INDIndia East UCBB0.00.00022403See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
PAKPakistan Baloch0.000066See
PHLPhilippines Ivatan0.00.000050See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
PNGPapua New Guinea Wanigela Keapara0.000066See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina Inner Mongolia Region0.0000102See
CHNChina Guangzhou0.0000102See
AUSAustralia Yuendumu Aborigine0.0000191See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
USAUSA Alaska Yupik0.0000252See
SGPSingapore SGVP Malay MAS0.000089See
SGPSingapore SGVP Chinese CHS0.000096See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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