Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 243 time(s) and present in 215 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CMRCameroon Baka Pygmy0.250010See
RUSRussia North Ossetian40.20.2402127See
USAUSA San Francisco Caucasian0.2130220See
IRLIreland South39.20.2120250See
DEUGermany Essen36.20.2090174See
ITAItaly South0.2060141See
CMRCameroon Sawa0.192013See
ENGEngland North West35.20.1900298See
THAThailand Northeast pop 20.1840400See
DEUGermany DKMS - Italy minority0.18261159See
FRAFrance West33.00.1814100See
GRCGreece pop 833.70.180783See
ESPSpain Andalusia Romani0.179099See
BFABurkina Faso Fulani0.174049See
AUSAustralia New South Wales Caucasian0.1730134See
FRAFrance Southeast31.50.1730130See
ZAFSouth Africa Caucasians0.1720102See
DEUGermany DKMS - Romania minority0.17031234See
DEUGermany DKMS - United Kingdom minority0.16831043See
CHESwitzerland Lausanne0.1674993See
SDNSudan Mixed29.50.1650200See
USAUSA African American Bethesda28.70.1650187See
NLDNetherlands UMCU32.80.164164See
GRCGreece pop 60.1632242See
DEUGermany DKMS - Bosnia and Herzegovina minority0.16291028See
DEUGermany DKMS - Croatia minority0.16142057See
GBRUnited Kingdom pop 329.80.1610604See
USAUSA NMDP European Caucasian0.16001242890See
UGAUganda Kampala0.1600161See
DEUGermany DKMS - Greece minority0.15821894See
NLDNetherlands Leiden0.15701305See
BRABrazil Mixed0.1560108See
DEUGermany DKMS - Portugal minority0.15551176See
DEUGermany DKMS - Netherlands minority0.15541374See
USAUSA Caucasian pop 20.1550265See
CZECzech Republic NMDR0.15245099See
CHESwitzerland Lugano0.15241169See
KENKenya Nandi0.1520240See
PAKPakistan Baloch0.152066See
USAUSA Caucasian pop 40.15141070See
DEUGermany pop 60.14948862See
BFABurkina Faso Rimaibe0.149047See
USAUSA NMDP Middle Eastern or North Coast of Africa0.147670890See
DEUGermany DKMS - German donors0.14733456066See
DEUGermany pop 80.147039689See
DEUGermany DKMS - Spain minority0.14531107See
ITAItaly North0.1440277See
USAUSA Caucasian Bethesda27.30.1440307See
CHESwitzerland Bern0.14383545See
CHESwitzerland Sion0.1434832See
POLPoland DKMS0.143320653See
CHESwitzerland Basel0.14311888See
CZECzech Republic0.1420106See
USAUSA NMDP Caribean Hispanic0.1418115374See
DEUGermany DKMS - France minority0.14141406See
DEUGermany DKMS - Austria minority0.14131698See
USAUSA NMDP Caribean Indian0.140014339See
ITAItaly pop 50.1400975See
CHESwitzerland Luzern0.13831553See
CHESwitzerland Geneva0.136080See
USAUSA African American0.1350252See
ZAFSouth Africa Natal Tamil0.135051See
USAUSA Philadelphia Caucasian25.50.1330141See
CHESwitzerland Aargau-Solothurn0.13121838See
CHESwitzerland Graubunden0.1308759See
USAUSA NMDP African0.130628557See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,24.20.13014335See
CMRCameroon Bamileke0.130077See
CHESwitzerland Zurich0.12934875See
CMRCameroon Beti0.1290174See
PRTPortugal Azores Terceira Island24.60.1272130See
TZATanzania Maasai23.10.1270336See
INDIndia New Delhi0.125071See
IRNIran Gorgan0.125064See
USAUSA African American pop 40.12402411See
SAUSaudi Arabia Guraiat and Hail24.70.1230213See
TURTurkey pop 50.1230142See
ZAFSouth Africa Worcester24.00.1230159See
CHESwitzerland St Gallen0.12302113See
CHESwitzerland Geneva pop 20.12251267See
ESPSpain Sevilla23.00.1223278See
ZMBZambia Lusaka0.122044See
USAUSA African American pop 30.1190564See
USAUSA NMDP American Indian South or Central America0.11905926See
USAUSA NMDP North American Amerindian0.117235791See
USAUSA NMDP African American pop 20.1170416581See
SGPSingapore SGVP. Indian INS0.117086See
KENKenya Luo0.1170265See
USAUSA South Texas Hispanic0.1170194See
USAUSA NMDP Caribean Black0.116133328See
USAUSA San Antonio Caucasian0.1152222See
BFABurkina Faso Mossi0.113053See
USAUSA San Diego20.50.1120496See
UGAUganda Kampala pop 20.1110175See
KORSouth Korea pop 10.1110324See
ESPSpain Andalusia0.110099See
USAUSA Hispanic0.1090234See
DEUGermany DKMS - Turkey minority0.10894856See
MEXMexico Mexico City Mestizo population0.1084143See
ZWEZimbabwe Harare Shona0.1060230See
LKASri Lanka Colombo19.60.1040714See
USAUSA NMDP South Asian Indian0.1039185391See
USAUSA Hispanic pop 20.10361999See
USAUSA NMDP Hispanic South or Central American0.1020146714See
RUSRussia Karelia0.10111075See
ENGEngland London Ashkenazi Jews0.1010500See
RUSRussia Arkhangelsk Pomor0.100063See
KENKenya, Nyanza Province, Luo tribe20.00.1000100See
USAUSA NMDP Alaska Native or Aleut0.09801376See
GEOGeorgia Tibilisi0.0980109See
MEXMexico Oaxaca Zapotec0.097090See
USAUSA NMDP Mexican or Chicano0.0917261235See
BGRBulgaria Romani0.091013See
ISRIsrael Arab Druze0.0900101See
COLColombia Bogotá Cord Blood16.50.08921463See
SENSenegal Niokholo Mandenka0.0870165See
USAUSA NMDP Southeast Asian0.086627978See
USAUSA North American Native0.0860187See
INDIndia Tamil Nadu0.08412492See
PAKPakistan Mixed Sindhi0.0830101See
MYSMalaysia Peninsular Malay15.70.0815951See
INDIndia Delhi pop 214.80.080090See
CHNChina Uyghur HIV negative0.079019See
RUSRussia Bering Island Aleuts0.0769104See
SGPSingapore Riau Malay0.0750132See
COLColombia North Chimila Amerindians0.074447See
SGPSingapore Thai0.0710100See
NICNicaragua Managua12.80.0696339See
GEOGeorgia Tibilisi Kurd0.069031See
AREUnited Arab Emirates Abu Dhabi0.067352See
PAKPakistan Kalash0.065069See
MLIMali Bandiagara0.0620138See
MYSMalaysia Peninsular Indian11.10.0572271See
BRABrazil Puyanawa11.30.0570150See
SGPSingapore SGVP Malay MAS0.056089See
PAKPakistan Burusho0.056092See
PAKPakistan Mixed Pathan0.0550100See
PAKPakistan Karachi Parsi0.055091See
AREUnited Arab Emirates Pop 10.0550570See
MEXMexico Mexico City Mestizo pop 20.0534234See
CHLChile Santiago Mixed10.00.051370See
GHAGhana Ga-Adangbe9.20.0458131See
USAUSA NMDP Hawaiian or other Pacific Islander0.044311499See
NZLNew Zealand Maori with Admixed History8.60.0430105See
VNMVietnam Hanoi Kinh pop 20.0410170See
INDIndia Central UCBB8.20.04084204See
SGPSingapore Javaneses0.040051See
RUSRussia Murmansk Saomi Mixed0.040070See
USAUSA Asian pop 20.03891772See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0370146See
KORSouth Korea pop 30.0370485See
NZLNew Zealand Polynesians with Admixed History7.40.037027See
USAUSA NMDP Korean0.035477584See
MEXMexico Chiapas Lacandon Mayans0.0344218See
AUSAustralia Cape York Peninsula Aborigine0.0340103See
PAKPakistan Brahui0.0340104See
INDIndia North UCBB6.50.03265849See
USAUSA NMDP Vietnamese0.032143540See
INDIndia West UCBB6.10.03065829See
INDIndia East UCBB5.90.02932403See
JORJordan Amman0.0280146See
CHNChina Southwest Dai0.0280124See
RUSRussia Transbaikal Territory Buryats5.00.0270150See
INDIndia South UCBB5.40.026811446See
CHNChina Inner Mongolia Region0.0250102See
ITAItaly North Pavia0.025081See
RUSRussia Nenet Mixed0.024055See
NZLNew Zealand Polynesians with Full Ancestry4.80.024021See
USAUSA NMDP Filipino0.024050614See
MYSMalaysia Peninsular Chinese4.60.0232194See
CHNChina Qinghai Province Hui0.0230110See
CHNChina Shanxi HIV negative0.023022See
NZLNew Zealand Maori with Full Ancestry4.30.022046See
AUSAustralia Groote Eylandt Aborigine0.021075See
RUSRussia Tuva pop 20.0200169See
USAUSA Hawaii Okinawa0.0190106See
USAUSA Asian0.0180358See
CHNChina Canton Han0.0170264See
INDIndia Northeast UCBB3.40.0169296See
CHNChina South Han0.0160284See
CHNChina Beijing0.015067See
PNGPapua New Guinea Wanigela Keapara0.014066See
DEUGermany DKMS - China minority0.01291282See
USAUSA NMDP Chinese0.010199672See
ASMAmerican Samoa0.010051See
CHNChina Hubei Han1.80.00913732See
MEXMexico Oaxaca Mixe0.009055See
TWNTaiwan Hakka1.80.009055See
HKGHong Kong Chinese BMDR0.00857595See
CHNChina Wuhan1.70.0080121See
MARMorocco Nador Metalsa pop 20.008073See
USAUSA South Dakota Lakota Sioux0.0080302See
CHNChina North Han pop 20.0079567See
USAUSA NMDP Japanese0.007324582See
CHNChina Guizhou Province Miao pop 20.006085See
USAUSA Arizona Gila River Amerindian0.0060492See
USAUSA Alaska Yupik0.0060252See
CHNChina Guangzhou0.0050102See
SGPSingapore SGVP Chinese CHS0.005096See
RUSRussia Belgorod region0.70.0033153See
CHNChina Yunnan Hani0.0030150See
CHNChina South Han pop 20.00231098See
TWNTaiwan Han Chinese0.0020504See
CHNChina Marrow Donor Registry0.0020600See
TWNTaiwan pop 20.0010364See
JPNJapan pop 160.000718604See
BRABrazil Vale do Ribeira Quilombos0.10.0000144See
CHNChina Guizhou Province Bouyei0.0000109See
CHNChina Guizhou Province Shui0.0000153See
CHNChina Tibet Region Tibetan0.0000158See
AUSAustralia Yuendumu Aborigine0.0000191See
CHNChina North Han0.0000105See
NCLNew Caledonia0.000065See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See
MEXMexico Oaxaca Mixtec0.0000103See
TWNTaiwan Minnan pop 10.00.0000102See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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