Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 249 time(s) and present in 234 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
SDNSudan East Rashaida48.10.279527See
INDIndia West Coast Parsi0.240050See
MARMorocco Settat Chaouya47.20.236098See
MARMorocco Atlantic Coast Chaouya0.236098See
INDIndia Mumbai Maratha0.222091See
KENKenya Nandi0.2170240See
SAUSaudi Arabia Guraiat and Hail37.00.2160213See
PAKPakistan Karachi Parsi0.214091See
CHNChina Shanxi HIV negative0.205022See
ZAFSouth Africa Worcester36.00.2010159See
UGAUganda Kampala pop 20.1910175See
CMRCameroon Bakola Pygmy34.00.187650See
KENKenya Luo0.1870265See
MARMorocco Nador Metalsa pop 20.183073See
IRNIran Gorgan0.179764See
ZAFSouth Africa Natal Tamil0.177051See
CMRCameroon Bamileke0.175077See
SGPSingapore SGVP. Indian INS0.173086See
AREUnited Arab Emirates Abu Dhabi0.163552See
MYSMalaysia Peninsular Indian28.80.1624271See
CZECzech Republic0.1600106See
INDIndia Tamil Nadu0.16002492See
CMRCameroon Sawa0.154013See
RUSRussia North Ossetian28.30.1535127See
BFABurkina Faso Fulani0.153049See
CMRCameroon Baka Pygmy0.150010See
KENKenya, Nyanza Province, Luo tribe30.00.1500100See
USAUSA NMDP South Asian Indian0.1391185391See
LKASri Lanka Colombo25.50.1370714See
INDIndia Delhi pop 222.20.136090See
IRNIran Tehran0.1320120See
ISRIsrael Arab Druze0.1300101See
RUSRussia Arkhangelsk Pomor0.130063See
ZWEZimbabwe Harare Shona0.1280230See
CMRCameroon Beti0.1260174See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.1220146See
LBNLebanon Mixed0.122097See
CHNChina Beijing0.121067See
PAKPakistan Mixed Sindhi0.1210101See
PAKPakistan Mixed Pathan0.1200100See
INDIndia West Bhil0.120050See
CHESwitzerland Sion0.1188832See
CHNChina Inner Mongolia Region0.1180102See
POLPoland DKMS0.117820653See
CHESwitzerland Graubunden0.1172759See
GEOGeorgia Tibilisi0.1170109See
ITAItaly South0.1170141See
RUSRussia Transbaikal Territory Buryats23.00.1170150See
UGAUganda Kampala0.1170161See
CHNChina North Han pop 20.1155567See
ESPSpain Andalusia Romani0.115099See
RUSRussia Tuva pop 20.1150169See
USAUSA African American0.1130252See
DEUGermany DKMS - Austria minority0.11261698See
CZECzech Republic NMDR0.11125099See
ENGEngland London Ashkenazi Jews0.1110500See
DEUGermany DKMS - Bosnia and Herzegovina minority0.11091028See
GBRUnited Kingdom pop 320.20.1100604See
USAUSA NMDP Southeast Asian0.107327978See
USAUSA Philadelphia Caucasian18.40.1070141See
FRAFrance Southeast20.00.1060130See
CHESwitzerland St Gallen0.10602113See
ITAItaly Bergamo19.80.1040101See
DEUGermany DKMS - Italy minority0.10341159See
USAUSA NMDP Middle Eastern or North Coast of Africa0.103270890See
PRTPortugal Center pop 20.1010562See
DEUGermany pop 80.100139689See
DEUGermany DKMS - United Kingdom minority0.10011043See
DEUGermany DKMS - China minority0.10001282See
CHNChina North Han0.1000105See
DEUGermany DKMS - Turkey minority0.09994856See
IRLIreland South18.80.0980250See
USAUSA Eastern European0.0980558See
PRTAzores Terceira Island0.0970130See
NLDNetherlands Leiden0.09701305See
PRTPortugal Azores Terceira Island19.30.0965130See
GRCGreece pop 818.10.096483See
CHESwitzerland Luzern0.09591553See
RUSRussia Nenet Mixed0.095055See
AUSAustralia New South Wales Caucasian0.0940134See
CHNChina Han HIV negative0.094072See
CHNChina Henan HIV negative0.094016See
DEUGermany pop 60.09388862See
USAUSA NMDP European Caucasian0.09321242890See
ITAItaly North Pavia0.093081See
USAUSA Caucasian pop 40.09251070See
ITAItaly North0.0920277See
RUSRussia Karelia0.09171075See
ESPSpain Andalusia0.091099See
DEUGermany DKMS - France minority0.09071406See
DEUGermany DKMS - Croatia minority0.09072057See
DEUGermany DKMS - Romania minority0.09051234See
INDIndia Tamil Nadu Nadar0.090061See
DEUGermany DKMS - Netherlands minority0.08951374See
CHESwitzerland Aargau-Solothurn0.08931838See
USAUSA African American pop 40.08862411See
NIRIreland Northern17.00.08801000See
USAUSA NMDP African0.087828557See
CHESwitzerland Lugano0.08721169See
USAUSA Caucasian pop 20.0870265See
USAUSA NMDP African American pop 20.0865416581See
CHNChina Qinghai Province Hui0.0860110See
ENGEngland North West16.40.0860298See
NLDNetherlands UMCU17.20.085964See
USAUSA African American pop 30.0850564See
RUSRussia Sakhalin Island Nivkhi0.085053See
CHESwitzerland Lausanne0.0840993See
ITAItaly pop 50.0830975See
JORJordan Amman0.0830146See
GRCGreece pop 60.0826242See
CHESwitzerland Zurich0.08224875See
USAUSA San Diego16.00.0820496See
RUSRussia Bering Island Aleuts0.0817104See
DEUGermany DKMS - Portugal minority0.08161176See
FRAFrance Corsica Island0.0810100See
CHESwitzerland Basel0.08061888See
ESPSpain Catalonia Girona0.080088See
ITAItaly Sardinia pop30.0800100See
CHNChina Uyghur HIV negative0.079019See
DEUGermany DKMS - Spain minority0.07891107See
USAUSA San Antonio Caucasian0.0788222See
ZAFSouth Africa Caucasians0.0780102See
USAUSA NMDP Caribean Indian0.078014339See
CHESwitzerland Bern0.07793545See
ESPSpain Sevilla13.30.0773278See
DEUGermany DKMS - Greece minority0.07721894See
CHESwitzerland Geneva pop 20.07501267See
BFABurkina Faso Rimaibe0.075047See
CHNChina Wuhan14.20.0750121See
USAUSA NMDP American Indian South or Central America0.07405926See
USAUSA NMDP Caribean Hispanic0.0740115374See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,14.20.07374335See
BRABrazil Puyanawa13.30.0730150See
CAFCentral African Republic Mbenzele Pygmy14.00.072636See
ESPSpain Majorca and Minorca0.072090See
USAUSA NMDP Caribean Black0.071633328See
RUSRussia Murmansk Saomi Mixed0.070070See
USAUSA NMDP North American Amerindian0.069735791See
USAUSA African American Bethesda12.80.0690187See
MKDMacedonia pop 40.0690216See
USAUSA Caucasian Bethesda13.60.0680307See
USAUSA Hispanic0.0680234See
SCOScotland Orkney13.50.067099See
USAUSA Asian pop 20.06521772See
INDIndia New Delhi0.063071See
CHNChina Marrow Donor Registry0.0630600See
DEUGermany Essen12.10.0620174See
USAUSA NMDP Hispanic South or Central American0.0614146714See
PAKPakistan Baloch0.061066See
USAUSA NMDP Mexican or Chicano0.0603261235See
MEXMexico Mexico City Mestizo pop 20.0598234See
CHNChina Sichuan HIV negative0.059034See
USAUSA Hispanic pop 20.05881999See
USAUSA San Francisco Caucasian0.0560220See
USAUSA North American Native0.0560187See
CHESwitzerland Geneva0.056080See
TWNTaiwan pop 20.0550364See
USAUSA NMDP Korean0.054877584See
MLIMali Bandiagara0.0540138See
PAKPakistan Brahui0.0530104See
USAUSA NMDP Alaska Native or Aleut0.05301376See
KORSouth Korea pop 30.0520485See
GEOGeorgia Tibilisi Kurd0.052031See
CHLChile Santiago Mixed10.00.051370See
COLColombia Bogotá Cord Blood10.10.05131463See
PAKPakistan Burusho0.051092See
SGPSingapore Javaneses0.050051See
CHNChina Yunnan Province Han0.0500101See
BFABurkina Faso Mossi0.047053See
NICNicaragua Managua9.20.0458339See
KORSouth Korea pop 10.0450324See
BGRBulgaria Romani0.045013See
USAUSA NMDP Chinese0.044799672See
CHNChina Tibet Region Tibetan0.0440158See
USAUSA South Texas Hispanic0.0430194See
USAUSA NMDP Vietnamese0.042643540See
IRNIran Baloch0.0420100See
THAThailand Northeast0.041066See
FRAFrance West8.00.0408100See
SGPSingapore SGVP Malay MAS0.039089See
SENSenegal Niokholo Mandenka0.0390165See
USAUSA Asian0.0360358See
CHNChina Guangzhou0.0360102See
ESPSpain Gipuzkoa Basque0.0350100See
ITAItaly North pop 36.70.033097See
ZMBZambia Lusaka0.033044See
THAThailand Northeast pop 20.0330400See
VNMVietnam Hanoi Kinh pop 20.0320170See
COLColombia North Chimila Amerindians0.031947See
USAUSA NMDP Hawaiian or other Pacific Islander0.031611499See
CHNChina South Han pop 20.03101098See
NZLNew Zealand Maori with Admixed History5.70.0290105See
MYSMalaysia Peninsular Malay5.60.0289951See
CHNChina Canton Han0.0280264See
AUSAustralia Cape York Peninsula Aborigine0.0280103See
CHNChina South Han0.0270284See
SGPSingapore SGVP Chinese CHS0.027096See
HKGHong Kong Chinese BMDR0.02637595See
BRABrazil Mixed0.0240108See
NZLNew Zealand Polynesians with Full Ancestry4.80.024021See
GHAGhana Ga-Adangbe4.60.0229131See
MYSMalaysia Peninsular Chinese3.60.0206194See
TWNTaiwan Han Chinese0.0200504See
NZLNew Zealand Polynesians with Admixed History3.70.019027See
SGPSingapore Riau Malay0.0190132See
TWNTaiwan Hakka3.60.018055See
JPNJapan pop 50.0170117See
JPNJapan Central0.0160371See
SGPSingapore Thai0.0160100See
TWNTaiwan Minnan pop 12.90.0150102See
AUSAustralia Groote Eylandt Aborigine0.014075See
USAUSA NMDP Filipino0.013750614See
MEXMexico Chihuahua Tarahumara0.011044See
USAUSA NMDP Japanese0.010524582See
TWNTaiwan Siraya2.00.010051See
CHNChina Guangdong Province Meizhou Han0.0100100See
JPNJapan pop 160.008118604See
USAUSA South Dakota Lakota Sioux0.0080302See
JPNJapan pop 30.00701018See
CHNChina Yunnan Hani0.0070150See
JPNJapan Kyoto and Osaka0.0060165See
JPNJapan pop 10.0050560See
CHNChina Yunnan Bulang0.0040116See
CHNChina Southwest Dai0.0040124See
MEXMexico Chiapas Lacandon Mayans0.0023218See
USAUSA Alaska Yupik0.0020252See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
PHLPhilippines Ivatan0.00.000050See
INDIndia Khandesh Region Pawra0.000050See
AUSAustralia Yuendumu Aborigine0.0000191See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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