Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.

Allele: 
   

B*18:01

 
Allele reported 263 time(s) and present in 233 population(s).

Population Phenotype
Frequency (%)
Allele
Frequency
(in_decimals)
Sample
Size
IMGT/HLA¹
Database
Distribution² Haplotype³
Association
Notesª
MYSMalaysia Perak Grik Jehai0.280025See
MYSMalaysia Kedah Baling Kensiu0.200025See
MYSMalaysia Kedah Kensiu38.10.190021See
MYSMalaysia Pahang Semai34.20.171038See
ITAItaly North pop 333.30.167097See
GRCGreece pop 60.1580242See
MYSMalaysia Jelebu Temuan0.146025See
MYSMalaysia Kelantan25.00.125028See
GEOGeorgia Svaneti Region Svan0.113080See
HRVCroatia0.1130150See
ROMRomania21.30.1130348See
PRTPortugal South0.112049See
ISRIsrael Iran Jews0.11168153See
GRCGreece pop 820.50.108483See
DEUGermany DKMS - Italy minority0.10661159See
SGPSingapore Riau Malay0.0990132See
DEUGermany DKMS - Greece minority0.09401894See
MYSMalaysia Mandailing18.50.093027See
BGRBulgaria0.091055See
DEUGermany DKMS - Romania minority0.08751234See
MYSMalaysia Champa17.20.086029See
ISRIsrael Arab Druze0.0850101See
DEUGermany DKMS - Croatia minority0.08482057See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,15.90.08354335See
HRVCroatia pop 40.08164000See
PRTAzores Central Islands0.080059See
PRTPortugal Center0.080050See
INDIndia Jalpaiguri Toto15.00.078040See
FINFinland0.078091See
SRBSerbia pop 215.70.0780102See
PRTAzores Oriental Islands0.077043See
CZECzech Republic0.0750106See
DEUGermany DKMS - Bosnia and Herzegovina minority0.07491028See
ISRIsrael Morocco Jews0.074536718See
POLPoland DKMS0.072720653See
USAUSA NMDP Middle Eastern or North Coast of Africa0.072470890See
ISRIsrael Kavkazi Jews0.07152840See
IRNIran Baloch0.0710100See
PHLPhilippines Ivatan14.00.070050See
POLPoland0.0700200See
ISRIsrael Tunisia Jews0.06949070See
USAUSA South Texas Hispanic0.0690194See
DEUGermany DKMS - Spain minority0.06781107See
THAThailand0.0670142See
TUNTunisia13.00.0670100See
ISRIsrael Druze0.06655914See
ISRIsrael Arab pop 20.066312301See
MYSMalaysia Peninsular Malay11.90.0657951See
PRTPortugal North0.065046See
ISRIsrael Libya Jews0.06493739See
CZECzech Republic NMDR0.06435099See
CUBCuba Caucasian12.90.064070See
ZWEZimbabwe Harare Shona0.0640230See
IDNIndonesia Java Western12.30.0640236See
TUNTunisia Gabes0.063195See
BRABrazil Belo Horizonte Caucasian12.60.063095See
CHESwitzerland Lugano0.06191169See
MEXMexico Mestizo12.20.061041See
GAZGaza11.90.059542See
RUSRussia Karelia0.05941075See
KENKenya0.0590144See
DEUGermany DKMS - Turkey minority0.05874856See
ITAItaly pop 50.0580975See
FRAFrance French Bone Marrow Donor Registry0.058042623See
IRNIran Kurds0.058060See
ISRIsrael Iraq Jews0.057913270See
GHAGhana Ga-Adangbe10.70.0573131See
SGPSingapore Thai0.0560100See
CHESwitzerland Bern0.05603545See
DEUGermany DKMS - France minority0.05511406See
ISRIsrael USSR Jews0.055045681See
BELBelgium10.20.051099See
SGPSingapore Javaneses0.051051See
BRABrazil Mixed0.0510108See
DEUGermany pop 80.050539689See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0500146See
UGAUganda Kampala0.0500161See
AUTAustria9.00.0500200See
DEUGermany DKMS - Portugal minority0.04921176See
USAUSA Hispanic0.0490234See
KENKenya Nandi0.0480240See
DEUGermany pop 60.04738862See
OMNOman8.50.0470118See
USAUSA San Francisco Caucasian0.0460220See
GEOGeorgia Tibilisi0.0460109See
DEUGermany DKMS - Austria minority0.04591698See
ENGEngland North West9.10.0450298See
BGRBulgaria Gipsy0.045013See
ARMArmenia combined Regions0.0450100See
USAUSA NMDP European Caucasian0.04431242890See
CHESwitzerland Lausanne0.0442993See
USAUSA Philadelphia Caucasian8.90.0440141See
USAUSA European American pop 20.04301245See
KENKenya Luo0.0430265See
FRAFrance Southeast8.50.0430130See
USAUSA NMDP Caribean Hispanic0.0427115374See
ISRIsrael Georgia Jews0.04244471See
USAUSA African American Bethesda8.50.0420187See
IRLIreland South8.40.0420250See
DEUGermany DKMS - Netherlands minority0.04151374See
USAUSA NMDP Hispanic South or Central American0.0411146714See
MARMorocco Settat Chaouya8.20.041098See
MARMorocco Atlantic Coast Chaouya0.041098See
USAUSA Caucasian pop 40.04101070See
USAUSA NMDP Mexican or Chicano0.0409261235See
CHESwitzerland Graubunden0.0407759See
CHESwitzerland Basel0.04061888See
ISRIsrael Argentina Jews0.04044307See
CHESwitzerland Luzern0.04021553See
RUSRussia Arkhangelsk Pomor0.040063See
MYSMalaysia Patani8.00.040025See
MEXMexico Chihuahua Chihuahua City Pop 28.00.039888See
PRTPortugal Azores Terceira Island7.90.0395130See
USAUSA Hispanic pop 20.03951999See
NLDNetherlands UMCU7.80.039164See
PRTAzores Terceira Island0.0390130See
USAUSA NMDP American Indian South or Central America0.03905926See
RUSRussia Bering Island Aleuts0.0385104See
CHESwitzerland Geneva pop 20.03811267See
INDIndia New Delhi0.038071See
ISRIsrael Poland Jews0.038013871See
ISRIsrael USA Jews0.03666058See
CHESwitzerland Aargau-Solothurn0.03631838See
USAUSA San Antonio Caucasian0.0361222See
GHAGhana Accre Asutuare Akan0.0360429See
CHESwitzerland Sion0.0359832See
DEUGermany DKMS - United Kingdom minority0.03581043See
CHLChile Santiago Mixed7.00.035670See
USAUSA African American pop 40.03572411See
ESPSpain Andalusia Gipsy0.035099See
KENKenya, Nyanza Province, Luo tribe6.00.0350100See
USAUSA NMDP Caribean Indian0.035014339See
RWARwanda0.0350280See
COLColombia Bogotá Cord Blood6.70.03451463See
USAUSA San Diego6.70.0340496See
GEOGeorgia Tibilisi Kurd0.034031See
AUSAustralia New South Wales Caucasian0.0340134See
ZMBZambia Lusaka0.034044See
ISRIsrael Ashkenazi Jews pop 30.03364625See
INDIndia Delhi pop 25.50.033090See
SDNSudan South Nuba6.50.033046See
NLDNetherlands Leiden0.03301305See
USAUSA NMDP North American Amerindian0.032335791See
USAUSA African American0.0320252See
USAUSA NMDP African American pop 20.0320416581See
USAUSA NMDP African0.031928557See
USAUSA NMDP Caribean Black0.031533328See
ISRIsrael YemenJews0.031415542See
CHESwitzerland Zurich0.03114875See
ZAFSouth Africa Natal Tamil0.031051See
STPSao Tome Island Angolar0.031032See
USAUSA NMDP Southeast Asian0.029427978See
NIRIreland Northern5.70.02901000See
USAUSA Caucasian pop 20.0280265See
USAUSA African American pop 80.0280605See
ZAFSouth Africa Worcester6.00.0280159See
MEXMexico Chiapas Lacandon Mayans0.0275218See
CMRCameroon Yaounde0.027092See
SENSenegal Niokholo Mandenka0.0270165See
USAUSA NMDP Alaska Native or Aleut0.02601376See
CHNChina Uyghur HIV negative0.026019See
NICNicaragua Managua5.10.0256339See
USAUSA NMDP South Asian Indian0.0252185391See
USAUSA NMDP Filipino0.024650614See
CHESwitzerland St Gallen0.02362113See
ISRIsrael Ethiopia Jews0.02335928See
CMRCameroon Beti0.0230174See
CHNChina Shanxi HIV negative0.023022See
CIVIvory Coast Adiopodoume Akan0.023044See
SDNSudan Mixed4.50.0230200See
USAUSA Caucasian Bethesda4.60.0230307See
MEXMexico Mexico City Tlalpan4.50.0227330See
SAUSaudi Arabia Guraiat and Hail3.90.0220213See
USAUSA North American Native0.0210187See
ZAFSouth Africa Natal Zulu4.00.0200100See
THAThailand pop 30.020049See
COLColombia North Wiwa El Encanto0.019252See
SWESweden Southern Sami0.0190130See
INDIndia Mumbai Maratha0.019091See
NCLNew Caledonia0.019065See
NZLNew Zealand Polynesians with Admixed History3.70.019027See
ISRIsrael Bukhara Jews0.01862317See
LKASri Lanka Colombo3.40.0180714See
MEXMexico Veracruz Xalapa3.60.017984See
INDIndia Tamil Nadu0.01792492See
MEXMexico Mexico City Mestizo pop 20.0171234See
UGAUganda Kampala pop 20.0170175See
USAUSA NMDP Hawaiian or other Pacific Islander0.016811499See
IRNIran Gorgan0.016064See
CHNChina Southwest Dai0.0160124See
STPSao Tome Island Forro0.015066See
PNGPapua New Guinea Wanigela Keapara0.015066See
IRNIran Gorgan0.015069See
CMRCameroon Bamileke0.013077See
USAUSA Asian pop 20.01161772See
RUSRussia Tuva pop 20.0110169See
USAUSA Asian0.0110358See
USAUSA NMDP Vietnamese0.010843540See
AUSAustralia Cape York Peninsula Aborigine0.0100103See
NZLNew Zealand Maori with Admixed History1.90.0100105See
INDIndia Andhra Pradesh Golla0.0100111See
JORJordan Amman0.0100146See
AREUnited Arab Emirates Abu Dhabi0.009652See
CHNChina South Han0.0090284See
CHNChina Qinghai Province Hui0.0090110See
CHNChina Canton Han0.0090264See
PNGPapua New Guinea Madang0.009065See
MLIMali Bandiagara0.0070138See
SGPSingapore Chinese1.30.0070149See
USAUSA South Dakota Lakota Sioux0.0070302See
USAUSA Arizona Pima0.0060100See
SGPSingapore Chinese Han0.006094See
USAUSA Alaska Yupik0.0060252See
VNMVietnam Hanoi Kinh pop 20.0060170See
CHNChina Inner Mongolia Region0.0050102See
DEUGermany DKMS - China minority0.00471282See
CHNChina Beijing Shijiazhuang Tianjian Han0.0040618See
HKGHong Kong Chinese cord blood registry0.00363892See
CHNChina Jiangsu Province Han0.0034334See
HKGHong Kong Chinese BMDR0.00317595See
CHNChina Jiangsu Han0.00303238See
SWESweden Northern Sami0.0030154See
GTMGuatemala Mayan0.0030132See
USAUSA NMDP Chinese0.002699672See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0021233See
USAUSA NMDP Japanese0.002124582See
CHNChina Marrow Donor Registry0.0020600See
TWNTaiwan Han Chinese0.0010504See
HKGHong Kong Chinese0.20.0010569See
USAUSA NMDP Korean0.000677584See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000546682See
JPNJapan pop 160.000118604See
INDIndia West Coast Parsi0.000050See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
AUSAustralia Yuendumu Aborigine0.0000191See
KORSouth Korea pop 30.0000485See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
CUBCuba Mulatto0.00.000042See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CHNChina Tibet Region Tibetan0.0000158See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CHNChina North Han0.0000105See

Frequency data at lower resolution for this allele can be found in links below


Allele  Number of Populations 

Notes:

* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


   

Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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