Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 266 time(s) and present in 241 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
INDIndia West Coast Parsi0.160050See
CHNChina Jiangsu Han0.11603238See
CHNChina Shanxi HIV negative0.114022See
CHNChina Jiangsu Province Han0.1011334See
ISRIsrael Morocco Jews0.098836718See
CHNChina Han HIV negative0.094072See
CHNChina Henan HIV negative0.094016See
ISRIsrael Bukhara Jews0.08142317See
MYSMalaysia Patani16.00.080025See
CHNChina Beijing0.076067See
CMRCameroon Bakola Pygmy14.00.072650See
DEUGermany DKMS - China minority0.06721282See
USAUSA Philadelphia Caucasian11.90.0670141See
CZECzech Republic0.0660106See
GEOGeorgia Svaneti Region Svan0.063080See
CHNChina Qinghai Province Hui0.0590110See
GEOGeorgia Tibilisi0.0560109See
CHNChina Beijing Shijiazhuang Tianjian Han0.0550618See
POLPoland DKMS0.054520653See
RUSRussia Karelia0.04921075See
DEUGermany DKMS - Bosnia and Herzegovina minority0.04861028See
ISRIsrael Iraq Jews0.048513270See
CZECzech Republic NMDR0.04755099See
CHNChina Marrow Donor Registry0.0470600See
CHNChina Hubei Han8.80.04413732See
ISRIsrael USSR Jews0.043345681See
INDIndia Mumbai Maratha0.043091See
INDIndia West Bhil0.040050See
USAUSA San Antonio Caucasian0.0392222See
SRBSerbia pop 27.80.0390102See
DEUGermany DKMS - Turkey minority0.03894856See
RUSRussia Bering Island Aleuts0.0385104See
SGPSingapore SGVP. Indian INS0.038086See
DEUGermany DKMS - Austria minority0.03801698See
SDNSudan Mixed7.50.0380200See
CHNChina North Han0.0380105See
HRVCroatia pop 40.03764000See
DEUGermany DKMS - Italy minority0.03751159See
DEUGermany DKMS - Croatia minority0.03702057See
DEUGermany DKMS - Romania minority0.03571234See
ARMArmenia combined Regions0.0350100See
KORSouth Korea pop 30.0350485See
DEUGermany pop 80.034739689See
CHESwitzerland Graubunden0.0346759See
DEUGermany DKMS - German donors0.03433456066See
USAUSA San Diego6.70.0340496See
MYSMalaysia Champa6.90.034029See
GEOGeorgia Tibilisi Kurd0.034031See
ISRIsrael Poland Jews0.034013871See
ISRIsrael Ethiopia Jews0.03315928See
GRCGreece pop 60.0330242See
USAUSA European American pop 20.03301245See
RUSRussia Tuva pop 20.0330169See
USAUSA NMDP Korean0.032177584See
USAUSA NMDP Middle Eastern or North Coast of Africa0.031970890See
ISRIsrael Ashkenazi Jews pop 30.03194625See
ISRIsrael Argentina Jews0.03184307See
ISRIsrael USA Jews0.03146058See
DEUGermany pop 60.03108862See
TWNTaiwan pop 20.0310364See
KORSouth Korea pop 100.03094128See
ISRIsrael Kavkazi Jews0.03082840See
DEUGermany DKMS - Greece minority0.03061894See
CHESwitzerland Bern0.03023545See
GRCGreece pop 86.00.030183See
USAUSA Eastern European0.0300558See
ISRIsrael Arab Druze0.0300101See
ISRIsrael Tunisia Jews0.02939070See
DEUGermany DKMS - United Kingdom minority0.02921043See
USAUSA NMDP Chinese0.029199672See
CHESwitzerland Basel0.02911888See
CUBCuba Caucasian5.70.029070See
UGAUganda Kampala0.0280161See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0280146See
CAFCentral African Republic Mbenzele Pygmy5.50.027836See
CHESwitzerland St Gallen0.02762113See
CMRCameroon Yaounde0.027092See
USAUSA Caucasian Bethesda5.40.0270307See
PRTAzores Central Islands0.027059See
CHESwitzerland Lugano0.02691169See
TZATanzania Maasai5.40.0269336See
ISRIsrael Arab pop 20.026812301See
CHESwitzerland Sion0.0261832See
CHNChina Uyghur HIV negative0.026019See
CHESwitzerland Luzern0.02581553See
USAUSA Caucasian pop 40.02511070See
ISRIsrael Libya Jews0.02503739See
NLDNetherlands Leiden0.02501305See
MEXMexico Mestizo4.90.024041See
USAUSA NMDP European Caucasian0.02391242890See
DEUGermany DKMS - Portugal minority0.02341176See
USAUSA Asian pop 20.02321772See
DEUGermany DKMS - Netherlands minority0.02331374See
CMRCameroon Beti0.0230174See
GNBGuinea Bissau0.023065See
KENKenya Nandi0.0230240See
CHESwitzerland Zurich0.02274875See
DEUGermany DKMS - France minority0.02241406See
CHESwitzerland Lausanne0.0221993See
ZWEZimbabwe Harare Shona0.0220230See
INDIndia Delhi pop 24.40.022090See
ISRIsrael Iran Jews0.02138153See
NICNicaragua Managua4.20.0211339See
MARMorocco Atlantic Coast Chaouya0.021098See
ITAItaly pop 50.0210975See
CHNChina Canton Han0.0210264See
MARMorocco Settat Chaouya4.20.021098See
CHESwitzerland Aargau-Solothurn0.02021838See
BRABrazil Puyanawa4.00.0200150See
USAUSA Asian0.0200358See
FRAFrance French Bone Marrow Donor Registry0.019842623See
ISRIsrael Druze0.01915914See
USAUSA North American Native0.0190187See
CMRCameroon Bamileke0.019077See
HKGHong Kong Chinese3.70.0190569See
DEUGermany DKMS - Spain minority0.01851107See
USAUSA NMDP South Asian Indian0.0184185391See
TWNTaiwan Tzu Chi Morrow Donor Registry0.018246682See
USAUSA NMDP Southeast Asian0.018127978See
MYSMalaysia Kelantan3.60.018028See
CHNChina South Han0.0180284See
TWNTaiwan Hakka3.60.018055See
HKGHong Kong Chinese BMDR0.01727595See
HKGHong Kong Chinese cord blood registry0.01713892See
USAUSA NMDP American Indian South or Central America0.01705926See
SGPSingapore Chinese3.40.0170149See
NIRIreland Northern3.40.01701000See
TWNTaiwan Han Chinese0.0170504See
UGAUganda Kampala pop 20.0170175See
USAUSA NMDP North American Amerindian0.016435791See
USAUSA San Francisco Caucasian0.0160220See
SGPSingapore SGVP Chinese CHS0.016096See
INDIndia South UCBB3.20.015911446See
INDIndia West UCBB3.20.01585829See
NLDNetherlands UMCU3.10.015664See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,3.00.01524335See
KENKenya, Nyanza Province, Luo tribe3.00.0150100See
CHNChina Yunnan Province Han0.0150101See
TWNTaiwan Tzu Chi Cord Blood Bank0.0150710See
CHNChina Sichuan HIV negative0.015034See
SGPSingapore Thai0.0150100See
CHNChina Guangdong Province Meizhou Han0.0150100See
ZAFSouth Africa Natal Zulu3.00.0150100See
USAUSA Hispanic0.0150234See
CHNChina Guangzhou0.0150102See
INDIndia North UCBB2.90.01455849See
ISRIsrael Georgia Jews0.01424471See
INDIndia Andhra Pradesh Golla0.0140111See
USAUSA NMDP Mexican or Chicano0.0138261235See
INDIndia Tamil Nadu0.01332492See
AREUnited Arab Emirates Pop 10.0130570See
USAUSA NMDP Alaska Native or Aleut0.01301376See
PRTAzores Oriental Islands0.013043See
USAUSA Caucasian pop 20.0130265See
MEXMexico Mexico City Mestizo pop 20.0128234See
USAUSA NMDP Hispanic South or Central American0.0128146714See
USAUSA NMDP African0.012328557See
USAUSA African American0.0120252See
CUBCuba Mixed Race2.40.012042See
SGPSingapore Chinese Han0.012094See
USAUSA African American pop 80.0120605See
IRLIreland South2.40.0120250See
USAUSA Hispanic pop 20.01201999See
INDIndia Central UCBB2.20.01114204See
IDNIndonesia Java Western2.10.0110236See
MEXMexico Chihuahua Tarahumara0.011044See
TUNTunisia pop 30.0110104See
USAUSA African American pop 30.0110564See
PRTPortugal North0.011046See
ZMBZambia Lusaka0.011044See
KENKenya Luo0.0110265See
TUNTunisia Gabes0.010595See
ZAFSouth Africa Caucasians0.0100102See
PRTPortugal Center0.010050See
PRTPortugal South0.010049See
TWNTaiwan Siraya2.00.010051See
TWNTaiwan Minnan pop 12.00.0100102See
SAUSaudi Arabia Guraiat and Hail2.00.0100213See
SGPSingapore Javaneses0.010051See
THAThailand pop 30.010049See
TWNTaiwan pop 30.0100212See
USAUSA African American pop 40.00952411See
INDIndia East UCBB1.90.00942403See
COLColombia Bogotá Cord Blood1.80.00921463See
USAUSA NMDP Caribean Hispanic0.0088115374See
PRTPortugal Azores Terceira Island1.80.0088130See
GHAGhana Accre Asutuare Akan0.0080429See
STPSao Tome Island Forro0.008066See
PRTAzores Terceira Island0.0080130See
AUSAustralia New South Wales Caucasian0.0080134See
USAUSA NMDP Caribean Black0.008033328See
USAUSA NMDP African American pop 20.0078416581See
MYSMalaysia Peninsular Chinese1.60.0077194See
USAUSA NMDP Vietnamese0.007743540See
MYSMalaysia Peninsular Indian1.50.0074271See
MEXMexico Mexico City Mestizo population0.0070143See
USAUSA NMDP Caribean Indian0.007014339See
ENGEngland North West1.30.0070298See
VNMVietnam Hanoi Kinh pop 20.0060170See
LKASri Lanka Colombo1.10.0060714See
ZAFSouth Africa Worcester1.00.0060159See
CHESwitzerland Geneva pop 20.00531267See
MYSMalaysia Peninsular Malay1.10.0053951See
CHLChile Santiago Mixed1.00.005070See
ESPSpain Andalusia Romani0.005099See
SGPSingapore Riau Malay0.0050132See
IRNIran Baloch0.0050100See
MEXMexico Guadalajara Mestizo pop 20.0050103See
BRABrazil Belo Horizonte Caucasian1.10.005095See
USAUSA NMDP Hawaiian or other Pacific Islander0.004911499See
USAUSA NMDP Filipino0.004850614See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0043233See
CHNChina Yunnan Bulang0.0040116See
JPNJapan pop 50.0040117See
MLIMali Bandiagara0.0040138See
USAUSA NMDP Japanese0.003724582See
CHNChina Yunnan Hani0.0030150See
CHNChina Tibet Region Tibetan0.0030158See
JPNJapan Central0.0030371See
JPNJapan pop 160.002918604See
MEXMexico Chiapas Lacandon Mayans0.0023218See
JPNJapan pop 30.00201018See
INDIndia Northeast UCBB0.30.0017296See
ISRIsrael YemenJews0.001615542See
MEXMexico Mexico City Tlalpan0.30.0015330See
SGPSingapore SGVP Malay MAS0.000089See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CPVCape Verde Northwestern Islands0.000062See
CPVCape Verde Southeastern Islands0.000062See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
USAUSA Alaska Yupik0.0000252See
MARMorocco Nador Metalsa pop 20.000073See
AUSAustralia Yuendumu Aborigine0.0000191See
USAUSA African American Bethesda0.00.0000187See
INDIndia Khandesh Region Pawra0.000050See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
STPSao Tome Island Angolar0.000032See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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