Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 172 time(s) and present in 98 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
GHAGhana Ga-Adangbe7.60.0382131See
SENSenegal Niokholo Mandenka0.0380165See
MARMorocco Settat Chaouya5.40.027098See
MARMorocco Atlantic Coast Chaouya0.027098See
ZMBZambia Lusaka0.023044See
GNBGuinea Bissau Balanta0.021048See
CMRCameroon Bamileke0.019077See
ESPSpain Majorca and Minorca0.017090See
MLIMali Bandiagara0.0150138See
USAUSA Spain Ancestry0.0130279See
CHESwitzerland Basel0.01191888See
BFABurkina Faso Fulani0.010049See
CMRCameroon Bakola Pygmy2.00.010050See
USAUSA African American0.0100252See
CPVCape Verde Southeastern Islands0.008062See
GNBGuinea Bissau0.008065See
STPSao Tome Island Forro0.008066See
ECUEcuador Amerindians0.007963See
CHLChile Mapuche0.007766See
USAUSA NMDP Caribean Black0.007733328See
MEXMexico Tixcacaltuyub Maya0.007567See
USAUSA NMDP African0.007428557See
USAUSA NMDP African American pop 20.0074416581See
USAUSA African American pop 30.0070564See
USAUSA African American pop 40.00712411See
USAUSA African American pop 20.0070149See
USAUSA Caucasian pop 30.006088See
CMRCameroon Beti0.0060174See
ESPSpain Catalonia Girona0.006088See
BRABrazil Belo Horizonte Caucasian1.10.005095See
BRABrazil Pernambuco Mixed0.0050101See
BRABrazil Mixed0.0050108See
USAUSA NMDP Caribean Hispanic0.0042115374See
CHESwitzerland Lugano0.00401169See
GTMGuatemala Mayan0.0040132See
MNGMongolia Buryat0.0040141See
CHESwitzerland Zurich0.00344875See
MEXMexico Mexico City Tlalpan0.60.0030330See
UGAUganda Kampala0.0030161See
USAUSA NMDP Caribean Indian0.003014339See
ZAFSouth Africa Worcester1.00.0030159See
USAUSA Hispanic pop 20.00251999See
USAUSA Mexican American Mestizo0.0020553See
USAUSA San Francisco Caucasian0.0020220See
USAUSA Italy Ancestry0.0020273See
ZWEZimbabwe Harare Shona0.0020230See
USAUSA Caucasian pop 40.00191070See
USAUSA NMDP Hispanic South or Central American0.0016146714See
TZATanzania Maasai0.30.0015336See
USAUSA NMDP Mexican or Chicano0.0013261235See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.30.00134335See
ISRIsrael Tunisia Jews0.00139070See
DEUGermany DKMS - France minority0.00111406See
USAUSA NMDP American Indian South or Central America0.00105926See
ISRIsrael Morocco Jews0.000936718See
DEUGermany DKMS - United Kingdom minority0.00101043See
ISRIsrael Libya Jews0.00083739See
DEUGermany DKMS - Portugal minority0.00091176See
HRVCroatia pop 40.00074000See
CHESwitzerland Bern0.00073545See
USAUSA NMDP North American Amerindian0.000735791See
ISRIsrael Argentina Jews0.00074307See
COLColombia Bogotá Cord Blood0.10.00071463See
ISRIsrael Arab pop 20.000512301See
ENGEngland Manchester0.10.00051640See
DEUGermany DKMS - Croatia minority0.00052057See
DEUGermany DKMS - Spain minority0.00051107See
DEUGermany DKMS - Italy minority0.00041159See
DEUGermany DKMS - Romania minority0.00041234See
ISRIsrael USA Jews0.00036058See
ISRIsrael Ashkenazi Jews pop 30.00034625See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000370890See
DEUGermany DKMS - Netherlands minority0.00041374See
DEUGermany DKMS - Turkey minority0.00024856See
DEUGermany pop 80.000239689See
CZECzech Republic NMDR0.00025099See
DEUGermany DKMS - Greece minority0.00031894See
DEUGermany DKMS - German donors0.00023456066See
ISRIsrael Poland Jews0.000213871See
ISRIsrael Ethiopia Jews0.00025928See
ISRIsrael Druze0.00025914See
USAUSA NMDP European Caucasian0.00011242890See
USAUSA NMDP Filipino0.000150614See
USAUSA NMDP Hawaiian or other Pacific Islander0.000011499See
ISRIsrael Iraq Jews0.000013270See
USAUSA NMDP Southeast Asian0.000027978See
USAUSA NMDP Vietnamese0.000043540See
ISRIsrael YemenJews0.000015542See
USAUSA NMDP Chinese0.000099672See
USAUSA NMDP Korean0.000077584See
ISRIsrael USSR Jews0.000045681See
USAUSA NMDP South Asian Indian0.0000185391See
USAUSA Hispanic0.0000234See
USAUSA North American Native0.0000187See
USAUSA San Antonio Caucasian0.0000222See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian pop 20.0000265See
PHLPhilippines Ivatan0.00.000050See
POLPoland DKMS0.000120653See
STPSao Tome Island Angolar0.000032See
SCOScotland Orkney0.00.000099See
SDNSudan Mixed0.00.0000200See
SGPSingapore Chinese0.00.0000149See
ITAItaly Sardinia pop30.0000100See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
KORSouth Korea pop 30.0000485See
MEXMexico Mestizo0.00.000041See
MARMorocco Nador Metalsa pop 20.000073See
NIRIreland Northern0.00.00001000See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
HKGHong Kong Chinese0.00.0000569See
ESPSpain Gipuzkoa Basque0.0000100See
FRAFrance Corsica Island0.0000100See
FRAFrance Grenoble, Nantes and Rennes0.00006094See
FRAFrance Rennes pop 30.0000200See
GNBGuinea Bissau Bijago0.000023See
GNBGuinea Bissau Fula0.000031See
GNBGuinea Bissau Papel0.000025See
CPVCape Verde Northwestern Islands0.000062See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
CHNChina North Han0.0000105See
CHNChina Tibet Region Tibetan0.0000158See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CAFCentral African Republic Mbenzele Pygmy0.00.000036See
CHESwitzerland Aargau-Solothurn0.00001838See
BFABurkina Faso Mossi0.000053See
BFABurkina Faso Rimaibe0.000047See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
USAUSA Asian pop 20.00001772See
USAUSA Asian0.0000358See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
ZAFSouth Africa Natal Zulu0.00.0000100See
ZAFSouth Africa Caucasians0.0000102See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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