Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 279 time(s) and present in 255 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
INDIndia West Coast Parsi0.160050See
GNBGuinea Bissau Bijago0.152023See
ISRIsrael Bukhara Jews0.14272317See
MLIMali Bandiagara0.1410138See
ZMBZambia Lusaka0.140044See
PAKPakistan Karachi Parsi0.139091See
CHNChina Henan HIV negative0.125016See
CHNChina Han HIV negative0.125072See
CHNChina Jiangsu Han0.11103238See
GHAGhana Ga-Adangbe19.90.1107131See
CHNChina Jiangsu Province Han0.1010334See
KENKenya, Nyanza Province, Luo tribe18.00.0950100See
ZAFSouth Africa Natal Zulu18.00.0950100See
JORJordan Amman0.0930146See
PAKPakistan Kalash0.092069See
ZWEZimbabwe Harare Shona0.0910230See
CHNChina Shanxi HIV negative0.091022See
CHNChina Beijing0.090067See
USAUSA African American pop 30.0820564See
ISRIsrael Ethiopia Jews0.08015928See
MYSMalaysia Patani16.00.080025See
USAUSA NMDP Caribean Black0.072033328See
USAUSA African American pop 40.06912411See
USAUSA NMDP African0.068528557See
USAUSA NMDP African American pop 20.0685416581See
MARMorocco Atlantic Coast Chaouya0.068098See
SDNSudan Mixed12.00.0680200See
MARMorocco Settat Chaouya13.60.068098See
KENKenya Luo0.0640265See
USAUSA African American Bethesda11.90.0640187See
UGAUganda Kampala pop 20.0630175See
ISRIsrael Libya Jews0.06263739See
DEUGermany DKMS - China minority0.06121282See
ISRIsrael Iraq Jews0.061213270See
INDIndia Khandesh Region Pawra0.060050See
STPSao Tome Island Forro0.060066See
USAUSA African American pop 20.0570149See
PAKPakistan Mixed Pathan0.0560100See
CPVCape Verde Northwestern Islands0.056062See
CMRCameroon Yaounde0.055092See
IRNIran Gorgan0.055064See
ISRIsrael Arab pop 20.054812301See
ISRIsrael Tunisia Jews0.05179070See
CHNChina Beijing Shijiazhuang Tianjian Han0.0500618See
USAUSA African American0.0500252See
KENKenya Nandi0.0480240See
CHNChina Sichuan HIV negative0.044034See
TUNTunisia pop 30.0440104See
CHESwitzerland Luzern0.04381553See
GRCGreece pop 88.40.042283See
CHNChina Marrow Donor Registry0.0420600See
ZAFSouth Africa Worcester8.00.0410159See
NICNicaragua Managua8.10.0404339See
CMRCameroon Beti0.0400174See
MEXMexico Mexico City Tlalpan7.90.0394330See
CHNChina Inner Mongolia Region0.0390102See
ISRIsrael Kavkazi Jews0.03862840See
GNBGuinea Bissau0.038065See
CMRCameroon Sawa0.038013See
CHNChina North Han0.0380105See
SENSenegal Niokholo Mandenka0.0380165See
SDNSudan East Rashaida7.40.037727See
KORSouth Korea pop 30.0350485See
ISRIsrael Poland Jews0.034713871See
ITAItaly pop 50.0340975See
MYSMalaysia Champa6.90.034029See
INDIndia Delhi pop 26.70.033090See
ISRIsrael USSR Jews0.032945681See
KORSouth Korea pop 100.03204128See
CMRCameroon Bamileke0.032077See
CPVCape Verde Southeastern Islands0.032062See
PAKPakistan Baloch0.032066See
USAUSA San Diego5.80.0320496See
USAUSA NMDP Korean0.031777584See
UGAUganda Kampala0.0310161See
TWNTaiwan pop 20.0310364See
SGPSingapore Thai0.0310100See
USAUSA South Texas Hispanic0.0300194See
USAUSA NMDP Caribean Indian0.030014339See
ARMArmenia combined Regions0.0300100See
ISRIsrael Arab Druze0.0300101See
USAUSA NMDP Caribean Hispanic0.0294115374See
ISRIsrael Ashkenazi Jews pop 30.02934625See
AREUnited Arab Emirates Abu Dhabi0.028852See
CHESwitzerland Geneva pop 20.02861267See
USAUSA NMDP Middle Eastern or North Coast of Africa0.028370890See
DEUGermany DKMS - Italy minority0.02801159See
USAUSA NMDP Chinese0.027499672See
CHNChina Qinghai Province Hui0.0270110See
USAUSA Hispanic0.0260234See
USAUSA Philadelphia Caucasian5.20.0260141See
USAUSA Caucasian Bethesda5.20.0260307See
DEUGermany DKMS - Turkey minority0.02544856See
BRABrazil Mixed0.0250108See
CHESwitzerland Aargau-Solothurn0.02431838See
CHESwitzerland Basel0.02381888See
MEXMexico Veracruz Xalapa4.80.023884See
FRAFrance Southeast4.60.0230130See
MEXMexico Chihuahua Chihuahua City Pop 24.50.022788See
IRNIran Baloch0.0220100See
COLColombia North Chimila Amerindians0.021247See
USAUSA San Antonio Caucasian0.0211222See
USAUSA North American Native0.0210187See
USAUSA Hispanic pop 20.02111999See
SAUSaudi Arabia Guraiat and Hail4.20.0210213See
BRABrazil Belo Horizonte Caucasian4.20.021095See
GNBGuinea Bissau Balanta0.021048See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0210146See
USAUSA Asian pop 20.02061772See
PRTPortugal Center0.020050See
GNBGuinea Bissau Papel0.020025See
USAUSA NMDP Hispanic South or Central American0.0199146714See
SGPSingapore SGVP. Indian INS0.019086See
CZECzech Republic0.0190106See
CZECzech Republic NMDR0.01895099See
DEUGermany DKMS - France minority0.01891406See
DEUGermany DKMS - Greece minority0.01871894See
GRCGreece pop 60.0186242See
CHESwitzerland Bern0.01813545See
CHESwitzerland St Gallen0.01802113See
HKGHong Kong Chinese3.30.0180569See
TWNTaiwan Hakka3.60.018055See
MYSMalaysia Kelantan3.60.018028See
USAUSA Asian0.0180358See
COLColombia Bogotá Cord Blood3.60.01781463See
HKGHong Kong Chinese cord blood registry0.01753892See
POLPoland DKMS0.017520653See
USAUSA NMDP South Asian Indian0.0173185391See
HKGHong Kong Chinese BMDR0.01727595See
GEOGeorgia Tibilisi Kurd0.017031See
IRNIran Kurds0.017060See
CHNChina Canton Han0.0170264See
BRABrazil Terena3.30.017060See
USAUSA Caucasian pop 30.017088See
USAUSA NMDP Southeast Asian0.016927978See
TWNTaiwan Tzu Chi Morrow Donor Registry0.016746682See
DEUGermany DKMS - Romania minority0.01661234See
DEUGermany DKMS - Bosnia and Herzegovina minority0.01651028See
USAUSA NMDP Mexican or Chicano0.0162261235See
DEUGermany pop 80.016239689See
CHNChina South Han0.0160284See
GNBGuinea Bissau Fula0.016031See
STPSao Tome Island Angolar0.016032See
USAUSA Caucasian pop 40.01591070See
ECUEcuador Amerindians0.015963See
TUNTunisia Gabes0.015795See
ZAFSouth Africa Caucasians0.0150102See
AUSAustralia New South Wales Caucasian0.0150134See
DEUGermany DKMS - Austria minority0.01501698See
CHNChina Yunnan Province Han0.0150101See
DEUGermany DKMS - Spain minority0.01491107See
ISRIsrael Iran Jews0.01478153See
DEUGermany DKMS - Portugal minority0.01451176See
MARMorocco Nador Metalsa pop 20.014073See
USAUSA NMDP American Indian South or Central America0.01405926See
USAUSA San Francisco Caucasian0.0140220See
USAUSA NMDP Vietnamese0.013943540See
HRVCroatia pop 40.01314000See
TWNTaiwan Tzu Chi Cord Blood Bank0.0130710See
SGPSingapore Chinese2.70.0130149See
NLDNetherlands Leiden0.01301305See
USAUSA NMDP European Caucasian0.01301242890See
MYSMalaysia Peninsular Indian2.60.0129271See
CHESwitzerland Sion0.0129832See
MEXMexico Mexico City Mestizo pop 20.0128234See
DEUGermany DKMS - Netherlands minority0.01271374See
CHESwitzerland Zurich0.01264875See
RUSRussia Karelia0.01261075See
DEUGermany DKMS - Croatia minority0.01242057See
DEUGermany pop 60.01248862See
CUBCuba Mulatto2.40.012042See
SGPSingapore Chinese Han0.012094See
TWNTaiwan Han Chinese0.0120504See
MEXMexico Mestizo2.40.012041See
MKDMacedonia pop 40.0120216See
FRAFrance French Bone Marrow Donor Registry0.011842623See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,2.30.01144335See
INDIndia Tamil Nadu0.01122492See
IDNIndonesia Java Western2.10.0110236See
INDIndia Andhra Pradesh Golla0.0110111See
USAUSA Caucasian pop 20.0110265See
MEXMexico Chihuahua Tarahumara0.011044See
MNGMongolia Buryat0.0110141See
NIRIreland Northern2.20.01101000See
PAKPakistan Brahui0.0110104See
SGPSingapore SGVP Chinese CHS0.011096See
PRTPortugal North0.011046See
USAUSA NMDP North American Amerindian0.010935791See
MYSMalaysia Peninsular Chinese2.10.0103194See
CHESwitzerland Lausanne0.0102993See
CMRCameroon Bakola Pygmy2.00.010050See
INDIndia West Bhil0.010050See
TWNTaiwan Minnan pop 12.00.0100102See
TWNTaiwan Siraya2.00.010051See
ZAFSouth Africa Natal Tamil0.010051See
USAUSA Eastern European0.0100558See
COLColombia North Wiwa El Encanto0.009652See
DEUGermany DKMS - United Kingdom minority0.00961043See
CHESwitzerland Lugano0.00911169See
USAUSA NMDP Alaska Native or Aleut0.00901376See
TWNTaiwan pop 30.0090212See
PRTAzores Central Islands0.009059See
PRTPortugal Azores Terceira Island1.80.0088130See
ISRIsrael Georgia Jews0.00854471See
ISRIsrael Morocco Jews0.008436718See
PRTAzores Terceira Island0.0080130See
NLDNetherlands UMCU1.60.007864See
MYSMalaysia Peninsular Malay1.50.0074951See
ENGEngland North West1.30.0070298See
GTMGuatemala Mayan0.0070132See
CHESwitzerland Graubunden0.0070759See
ISRIsrael Druze0.00625914See
ISRIsrael USA Jews0.00556058See
GEOGeorgia Tibilisi0.0050109See
CHNChina Guangzhou0.0050102See
CHLChile Santiago Mixed1.00.005070See
MEXMexico Guadalajara Mestizo pop 20.0050103See
MEXMexico Mixtec0.005097See
NZLNew Zealand Maori with Admixed History1.00.0050105See
PAKPakistan Burusho0.005092See
RUSRussia Bering Island Aleuts0.0048104See
MEXMexico Chiapas Lacandon Mayans0.0046218See
USAUSA NMDP Filipino0.004550614See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0043233See
ISRIsrael YemenJews0.004115542See
IRLIreland South0.80.0040250See
LKASri Lanka Colombo0.80.0040714See
JPNJapan pop 50.0040117See
CHNChina Yunnan Bulang0.0040116See
CHNChina Southwest Dai0.0040124See
SGPSingapore Riau Malay0.0040132See
ISRIsrael Argentina Jews0.00354307See
CHNChina Yunnan Hani0.0030150See
CHNChina Tibet Region Tibetan0.0030158See
RUSRussia Tuva pop 20.0030169See
VNMVietnam Hanoi Kinh pop 20.0030170See
USAUSA NMDP Hawaiian or other Pacific Islander0.002911499See
JPNJapan pop 160.002118604See
USAUSA Alaska Yupik0.0020252See
USAUSA NMDP Japanese0.001924582See
JPNJapan Central0.0010371See
JPNJapan pop 30.00101018See
ITAItaly North pop 30.00.000097See
INDIndia Mumbai Maratha0.000091See
AUSAustralia Yuendumu Aborigine0.0000191See
BRABrazil Vale do Ribeira Quilombos0.10.0000144See
CAFCentral African Republic Mbenzele Pygmy0.00.000036See
CMRCameroon Baka Pygmy0.000010See
CUBCuba Caucasian0.00.000070See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
PHLPhilippines Ivatan0.00.000050See
PRTAzores Oriental Islands0.000043See
PRTPortugal South0.000049See
PAKPakistan Mixed Sindhi0.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Thao0.00.000030See
SGPSingapore SGVP Malay MAS0.000089See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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