Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 144 time(s) and present in 82 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ITAItaly North pop 33.80.019097See
CHESwitzerland Geneva pop 20.01431267See
PRTPortugal North0.011046See
INDIndia West Coast Parsi0.010050See
IRNIran Yazd0.008956See
CHESwitzerland Aargau-Solothurn0.00821838See
CPVCape Verde Northwestern Islands0.008062See
ECUEcuador Amerindians0.007963See
USAUSA Caucasian Bethesda1.40.0070307See
CHESwitzerland Basel0.00671888See
UGAUganda Kampala0.0060161See
CHNChina Yunnan Province Lisu0.0060111See
CHLChile Santiago Mixed1.00.005070See
BRABrazil Belo Horizonte Caucasian1.10.005095See
CHESwitzerland Lausanne0.0045993See
CHESwitzerland Bern0.00413545See
USAUSA Philadelphia Caucasian0.70.0040141See
USAUSA Caucasian pop 20.0040265See
JPNJapan Okinawa Ryukyuan0.0040143See
CHESwitzerland Graubunden0.0037759See
SWESweden Northern Sami0.0030154See
USAUSA San Antonio Caucasian0.0030222See
USAUSA Caucasian0.50.002561655See
CHESwitzerland Zurich0.00244875See
USAUSA Hispanic0.0020234See
USAUSA Mexican American Mestizo0.0020553See
USAUSA San Francisco Caucasian0.0020220See
ITAItaly pop 50.0020975See
CRICosta Rica Central Valley Mestizo (G)0.40.0020221See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.40.00174335See
DEUGermany DKMS - Italy minority0.00131159See
DEUGermany DKMS - Croatia minority0.00102057See
DEUGermany DKMS - United Kingdom minority0.00101043See
NIRIreland Northern0.10.00101000See
NLDNetherlands Leiden0.00101305See
USAUSA NMDP Caribean Indian0.001014339See
USAUSA Hispanic pop 20.00101999See
USAUSA NMDP European Caucasian0.00101242890See
USAUSA NMDP Mexican or Chicano0.0009261235See
USAUSA NMDP Hispanic South or Central American0.0009146714See
DEUGermany pop 80.000939689See
USAUSA NMDP North American Amerindian0.000935791See
DEUGermany DKMS - Portugal minority0.00091176See
DEUGermany DKMS - Greece minority0.00081894See
USAUSA NMDP Caribean Hispanic0.0008115374See
DEUGermany DKMS - German donors0.00083456066See
POLPoland BMR0.10.000723595See
DEUGermany pop 60.00088862See
DEUGermany DKMS - France minority0.00071406See
POLPoland DKMS0.000720653See
RUSRussia Nizhny Novgorod, Russians0.10.00071510See
CZECzech Republic NMDR0.00065099See
HRVCroatia pop 40.00064000See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000670890See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00051028See
DEUGermany DKMS - Spain minority0.00051107See
USAUSA African American pop 40.00042411See
DEUGermany DKMS - Netherlands minority0.00041374See
DEUGermany DKMS - Austria minority0.00031698See
ISRIsrael Ashkenazi Jews pop 30.00034625See
USAUSA NMDP Caribean Black0.000233328See
USAUSA NMDP African0.000228557See
DEUGermany DKMS - Turkey minority0.00024856See
USAUSA Arizona Gila River Pima0.00023000See
USAUSA NMDP African American pop 20.0001416581See
ISRIsrael Argentina Jews0.00014307See
ISRIsrael Georgia Jews0.00014471See
ISRIsrael Bukhara Jews0.00012317See
ISRIsrael USSR Jews0.000145681See
ISRIsrael Poland Jews0.000113871See
USAUSA NMDP Filipino0.000050614See
ISRIsrael Libya Jews0.00003739See
USAUSA NMDP Hawaiian or other Pacific Islander0.000011499See
ISRIsrael Iraq Jews0.000013270See
ISRIsrael USA Jews0.00006058See
ISRIsrael YemenJews0.000015542See
SAUSaudi Arabia pop 6 (G)0.000028927See
USAUSA NMDP Vietnamese0.000043540See
USAUSA NMDP Chinese0.000099672See
USAUSA NMDP Korean0.000077584See
ZMBZambia Lusaka0.000044See
USAUSA Caucasian pop 40.00001070See
USAUSA North American Native0.0000187See
USAUSA Asian0.0000358See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA African American0.0000252See
USAUSA Asian pop 20.00001772See
USAUSA African American Bethesda0.00.0000187See
SGPSingapore Chinese0.00.0000149See
ZAFSouth Africa Natal Zulu0.00.0000100See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
GNBGuinea Bissau0.000065See
HKGHong Kong Chinese0.00.0000569See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
INDIndia Mumbai Maratha0.000091See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina North Han0.0000105See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CPVCape Verde Southeastern Islands0.000062See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
KORSouth Korea pop 30.0000485See
MLIMali Bandiagara0.0000138See
MEXMexico Mestizo0.00.000041See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
PRTPortugal Center0.000050See
PRTPortugal South0.000049See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
PAKPakistan Karachi Parsi0.000091See
PHLPhilippines Ivatan0.00.000050See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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