Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 209 time(s) and present in 171 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CHNChina Yunnan Bulang0.3660116See
PHLPhilippines Ivatan52.00.310050See
USAUSA Arizona Gila River Amerindian0.2990492See
TWNTaiwan Ami42.90.260098See
USAUSA New Mexico Canoncito Navajo0.244042See
MEXMexico Chihuahua Tarahumara0.227044See
SGPSingapore SGVP Malay MAS0.219089See
SGPSingapore Javaneses0.210051See
CHNChina Guizhou Province Shui0.2060153See
TWNTaiwan Taroko34.50.191055See
SGPSingapore Riau Malay0.1870132See
TWNTaiwan Atayal34.90.1840106See
CHNChina Guizhou Province Bouyei0.1770109See
INDIndia Northeast UCBB30.40.1740296See
USAUSA NMDP Vietnamese0.164443540See
MYSMalaysia Peninsular Malay30.30.1635951See
CHNChina Guangzhou0.1580102See
VNMVietnam Hanoi Kinh pop 20.1560170See
CHNChina Yunnan Hani0.1530150See
ASMAmerican Samoa0.150051See
CHNChina Yunnan Province Han0.1490101See
TWNTaiwan Pazeh25.50.136055See
CHNChina Canton Han0.1330264See
IRNIran Gorgan0.132864See
NZLNew Zealand Maori with Full Ancestry21.70.130046See
HKGHong Kong Chinese BMDR0.12827595See
CHNChina South Han0.1260284See
CHNChina Han HIV negative0.125072See
CHNChina Henan HIV negative0.125016See
CHNChina Beijing0.114067See
CHNChina Shanxi HIV negative0.114022See
NZLNew Zealand Maori with Admixed History21.00.1140105See
USAUSA Asian0.1130358See
JPNJapan pop 50.1090117See
TWNTaiwan Siraya17.60.108051See
TWNTaiwan Minnan pop 117.60.1080102See
USAUSA NMDP Chinese0.104399672See
USAUSA NMDP Filipino0.100250614See
USAUSA Hawaii Okinawa0.1000106See
CHNChina South Han pop 20.09931098See
KORSouth Korea pop 10.0990324See
TWNTaiwan Tsou19.60.098051See
TWNTaiwan pop 20.0970364See
BRABrazil Terena16.00.096060See
SGPSingapore SGVP Chinese CHS0.096096See
NZLNew Zealand Polynesians with Full Ancestry14.30.095021See
CHLChile Easter Island0.095021See
USAUSA NMDP Hawaiian or other Pacific Islander0.093111499See
DEUGermany DKMS - China minority0.09011282See
CHNChina North Han pop 20.0891567See
TWNTaiwan Bunun17.80.0890101See
JPNJapan pop 10.0860560See
MYSMalaysia Peninsular Chinese16.50.0851194See
TWNTaiwan Thao16.70.083030See
JPNJapan pop 30.08201018See
CHNChina Marrow Donor Registry0.0820600See
TWNTaiwan Han Chinese0.0810504See
CHNChina Southwest Dai0.0810124See
USAUSA Asian pop 20.07991772See
JPNJapan Kyoto and Osaka0.0790165See
CHNChina Hubei Han15.70.07853732See
SGPSingapore Thai0.0760100See
KORSouth Korea pop 30.0740485See
JPNJapan Central0.0740371See
NZLNew Zealand Polynesians with Admixed History11.10.074027See
USAUSA NMDP Korean0.073877584See
JPNJapan pop 160.073618604See
TWNTaiwan Hakka14.50.073055See
USAUSA NMDP Japanese0.068224582See
CHNChina Guizhou Province Miao pop 20.059085See
RUSRussia Tuva pop 20.0520169See
USAUSA NMDP Southeast Asian0.049927978See
INDIndia East UCBB9.90.04972403See
TWNTaiwan Saisiat9.80.049051See
MEXMexico Mexico City Mestizo pop 20.0470234See
RUSRussia Transbaikal Territory Buryats9.00.0470150See
BRABrazil Puyanawa9.30.0470150See
CHNChina Sichuan HIV negative0.044034See
ZAFSouth Africa Natal Tamil0.042051See
MEXMexico Mexico City Mestizo population0.0385143See
MEXMexico Oaxaca Zapotec0.037090See
USAUSA NMDP Mexican or Chicano0.0362261235See
LKASri Lanka Colombo6.20.0320714See
ZWEZimbabwe Harare Shona0.0290230See
INDIndia West UCBB5.80.02875829See
USAUSA NMDP South Asian Indian0.0283185391See
USAUSA Hispanic pop 20.02831999See
PNGPapua New Guinea Wanigela Keapara0.028066See
USAUSA NMDP Alaska Native or Aleut0.02801376See
MYSMalaysia Peninsular Indian5.50.0277271See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0270146See
PNGPapua New Guinea Madang0.026065See
INDIndia Central UCBB4.80.02404204See
USAUSA San Diego4.80.0240496See
USAUSA North American Native0.0240187See
USAUSA NMDP North American Amerindian0.022235791See
NCLNew Caledonia0.022065See
JORJordan Amman0.0210146See
PAKPakistan Mixed Pathan0.0200100See
AREUnited Arab Emirates Abu Dhabi0.019252See
SGPSingapore SGVP. Indian INS0.019086See
INDIndia Tamil Nadu0.01892492See
USAUSA South Dakota Lakota Sioux0.0180302See
INDIndia South UCBB3.60.017911446See
USAUSA Hispanic0.0170234See
GEOGeorgia Tibilisi Kurd0.017031See
ZAFSouth Africa Worcester3.00.0160159See
PAKPakistan Mixed Sindhi0.0150101See
PAKPakistan Baloch0.015066See
USAUSA NMDP Hispanic South or Central American0.0149146714See
USAUSA NMDP American Indian South or Central America0.01405926See
INDIndia North UCBB2.60.01315849See
COLColombia Bogotá Cord Blood2.50.01261463See
DEUGermany Essen2.30.0120174See
INDIndia Delhi pop 22.50.012090See
MEXMexico Chichen Itza Maya (prehispanic)0.010647See
COLColombia North Chimila Amerindians0.010647See
CHLChile Santiago Mixed2.00.010070See
PAKPakistan Burusho0.010092See
RUSRussia Bering Island Aleuts0.0096104See
NICNicaragua Managua1.80.0092339See
USAUSA South Texas Hispanic0.0080194See
DEUGermany DKMS - Turkey minority0.00614856See
GRCGreece pop 81.20.006083See
AUSAustralia Cape York Peninsula Aborigine0.0060103See
UGAUganda Kampala0.0060161See
AREUnited Arab Emirates Pop 10.0060570See
CHESwitzerland Sion0.0050832See
BRABrazil Mixed0.0050108See
GEOGeorgia Tibilisi0.0050109See
PAKPakistan Brahui0.0050104See
ZAFSouth Africa Caucasians0.0050102See
ENGEngland London Ashkenazi Jews0.0050500See
USAUSA Alaska Yupik0.0040252See
RUSRussia North Ossetian0.80.0039127See
ESPSpain Sevilla0.70.0036278See
RUSRussia Karelia0.00341075See
USAUSA NMDP Caribean Indian0.003014339See
USAUSA San Antonio Caucasian0.0030222See
MEXMexico Chiapas Lacandon Mayans0.0023218See
USAUSA NMDP Caribean Hispanic0.0021115374See
NLDNetherlands Leiden0.00201305See
USAUSA African American0.0020252See
USAUSA Eastern European0.0020558See
TZATanzania Maasai0.30.0016336See
DEUGermany DKMS - Greece minority0.00161894See
USAUSA NMDP Caribean Black0.001533328See
DEUGermany DKMS - Netherlands minority0.00151374See
DEUGermany DKMS - Italy minority0.00131159See
USAUSA African American pop 40.00122411See
USAUSA NMDP African0.001128557See
USAUSA NMDP Middle Eastern or North Coast of Africa0.001170890See
USAUSA NMDP African American pop 20.0011416581See
NIRIreland Northern0.10.00101000See
USAUSA Caucasian pop 40.00091070See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00071028See
DEUGermany DKMS - France minority0.00071406See
DEUGermany DKMS - Croatia minority0.00072057See
DEUGermany pop 80.000739689See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.10.00064335See
CZECzech Republic NMDR0.00055099See
USAUSA NMDP European Caucasian0.00041242890See
CHESwitzerland Bern0.00043545See
DEUGermany DKMS - Spain minority0.00051107See
DEUGermany DKMS - Romania minority0.00041234See
DEUGermany DKMS - German donors0.00033456066See
DEUGermany pop 60.00048862See
DEUGermany DKMS - Austria minority0.00031698See
POLPoland DKMS0.000320653See
GBRUnited Kingdom pop 30.00.0000604See
LBNLebanon Mixed0.000097See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Aargau-Solothurn0.00001838See
ITAItaly pop 50.0000975See
MEXMexico Oaxaca Mixtec0.0000103See
PAKPakistan Kalash0.000069See
MARMorocco Settat Chaouya0.00.000098See
USAUSA Caucasian pop 20.0000265See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
SENSenegal Niokholo Mandenka0.0000165See
IRNIran Tehran0.0000120See
CHESwitzerland Geneva0.000080See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
ZMBZambia Lusaka0.000044See
MARMorocco Nador Metalsa pop 20.000073See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
MLIMali Bandiagara0.0000138See
PAKPakistan Karachi Parsi0.000091See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
USAUSA Philadelphia Caucasian0.00.0000141See
CHNChina North Han0.0000105See
CHESwitzerland Zurich0.00004875See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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