Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 186 time(s) and present in 143 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
VENVenezuela Perja Mountain Bari0.239055See
MEXMexico Oaxaca Mixtec0.0880103See
USAUSA Arizona Pima0.0730100See
USAUSA Arizona Gila River Amerindian0.0730492See
MEXMexico Mexico City Mestizo pop 20.0684234See
USAUSA South Texas Hispanic0.0560194See
MEXMexico Oaxaca Jamiltepec Mixtec0.052096See
MEXMexico Mixtec0.052097See
MEXMexico Oaxaca Zapotec0.045090See
MEXMexico Tixcacaltuyub Maya0.037367See
USAUSA New Mexico Canoncito Navajo0.037042See
USAUSA NMDP Mexican or Chicano0.0287261235See
MEXMexico Mexico City Mestizo population0.0280143See
CHLChile Mapuche0.023866See
PNGPapua New Guinea Wanigela Keapara0.023066See
TUNTunisia pop 30.0230104See
MEXMexico Mexico City Tlalpan4.20.0212330See
USAUSA Hispanic pop 20.02031999See
BRABrazil Puyanawa4.00.0200150See
USAUSA North American Native0.0190187See
USAUSA NMDP American Indian South or Central America0.01805926See
USAUSA NMDP North American Amerindian0.017635791See
USAUSA Hispanic0.0170234See
CHESwitzerland Geneva pop 20.01631267See
BRABrazil Belo Horizonte Caucasian3.20.016095See
USAUSA South Dakota Lakota Sioux0.0150302See
USAUSA NMDP Hispanic South or Central American0.0146146714See
CUBCuba Caucasian2.90.014070See
MEXMexico Chiapas Lacandon Mayans0.0138218See
PRTAzores Oriental Islands0.013043See
CHESwitzerland St Gallen0.01182113See
GRCGreece pop 60.0118242See
AUSAustralia New South Wales Caucasian0.0110134See
PRTPortugal North0.011046See
MEXMexico Chichen Itza Maya (prehispanic)0.010647See
CHESwitzerland Aargau-Solothurn0.01011838See
ESPSpain Andalusia Romani0.010099See
PRTPortugal Center0.010050See
NZLNew Zealand Maori with Admixed History1.90.0100105See
CHLChile Santiago Mixed2.00.010070See
BRABrazil Terena1.70.009060See
NIRIreland Northern1.70.00901000See
ISRIsrael USA Jews0.00836058See
DEUGermany DKMS - United Kingdom minority0.00821043See
PRTAzores Terceira Island0.0080130See
USAUSA Caucasian pop 20.0080265See
CHESwitzerland Zurich0.00774875See
ISRIsrael Ashkenazi Jews pop 30.00764625See
CHESwitzerland Luzern0.00751553See
NLDNetherlands Leiden0.00701305See
BRABrazil Mixed0.0070108See
USAUSA San Francisco Caucasian0.0070220See
USAUSA NMDP Alaska Native or Aleut0.00701376See
USAUSA Philadelphia Caucasian1.50.0070141See
ISRIsrael Poland Jews0.006613871See
CHESwitzerland Sion0.0065832See
USAUSA NMDP European Caucasian0.00641242890See
USAUSA San Diego1.30.0060496See
ITAItaly pop 50.0060975See
MEXMexico Veracruz Xalapa1.20.006084See
GRCGreece pop 81.20.006083See
MEXMexico Chihuahua Chihuahua City Pop 21.10.005788See
DEUGermany DKMS - Austria minority0.00561698See
DEUGermany pop 60.00558862See
CHESwitzerland Bern0.00553545See
USAUSA NMDP Caribean Hispanic0.0055115374See
CHESwitzerland Graubunden0.0054759See
DEUGermany DKMS - German donors0.00523456066See
INDIndia Andhra Pradesh Golla0.0050111See
SRBSerbia pop 21.00.0050102See
USAUSA NMDP Caribean Indian0.005014339See
AREUnited Arab Emirates Pop 10.0050570See
USAUSA Eastern European0.0050558See
ISRIsrael Morocco Jews0.005036718See
DEUGermany DKMS - Spain minority0.00501107See
DEUGermany DKMS - Romania minority0.00491234See
RUSRussia Bering Island Aleuts0.0048104See
DEUGermany DKMS - Netherlands minority0.00491374See
DEUGermany pop 80.004739689See
USAUSA Caucasian pop 40.00471070See
CHESwitzerland Basel0.00451888See
PRTPortugal Azores Terceira Island0.90.0044130See
DEUGermany DKMS - Portugal minority0.00431176See
DEUGermany DKMS - Greece minority0.00421894See
COLColombia Bogotá Cord Blood0.80.00411463See
USAUSA NMDP Middle Eastern or North Coast of Africa0.004170890See
USAUSA African American0.0040252See
USAUSA European American pop 20.00401245See
CZECzech Republic NMDR0.00405099See
SWESweden Southern Sami0.0040130See
DEUGermany DKMS - France minority0.00391406See
CHESwitzerland Lausanne0.0038993See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.70.00334335See
RUSRussia Karelia0.00331075See
POLPoland DKMS0.003020653See
NICNicaragua Managua0.60.0030339See
HRVCroatia pop 40.00304000See
DEUGermany DKMS - Turkey minority0.00224856See
CHNChina Canton Han0.0020264See
DEUGermany DKMS - Croatia minority0.00192057See
MYSMalaysia Peninsular Indian0.40.0018271See
USAUSA African American pop 40.00192411See
USAUSA NMDP African American pop 20.0014416581See
USAUSA NMDP Hawaiian or other Pacific Islander0.001311499See
INDIndia North UCBB0.30.00135849See
DEUGermany DKMS - Italy minority0.00131159See
CHESwitzerland Lugano0.00121169See
USAUSA NMDP South Asian Indian0.0011185391See
ISRIsrael USSR Jews0.001045681See
USAUSA NMDP Southeast Asian0.001027978See
USAUSA NMDP Caribean Black0.001033328See
USAUSA African American pop 80.0010605See
LKASri Lanka Colombo0.30.0010714See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00101028See
USAUSA NMDP African0.000928557See
INDIndia West UCBB0.20.00095829See
INDIndia South UCBB0.10.000711446See
ISRIsrael Argentina Jews0.00074307See
SAUSaudi Arabia pop 6 (G)0.000728927See
ISRIsrael Arab pop 20.000612301See
INDIndia Tamil Nadu0.00062492See
INDIndia Central UCBB0.10.00064204See
INDIndia East UCBB0.10.00042403See
USAUSA NMDP Filipino0.000450614See
ISRIsrael Ethiopia Jews0.00035928See
USAUSA NMDP Japanese0.000224582See
USAUSA Asian pop 20.00031772See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000246682See
ISRIsrael Tunisia Jews0.00029070See
ISRIsrael Georgia Jews0.00014471See
USAUSA NMDP Chinese0.000199672See
USAUSA NMDP Vietnamese0.000143540See
ISRIsrael Iraq Jews0.000113270See
HKGHong Kong Chinese BMDR0.00017595See
ISRIsrael Iran Jews0.00018153See
USAUSA NMDP Korean0.000177584See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Asian0.0000358See
USAUSA San Antonio Caucasian0.0000222See
USAUSA Alaska Yupik0.0000252See
MEXMexico Mestizo0.00.000041See
HKGHong Kong Chinese0.00.0000569See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina North Han0.0000105See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CUBCuba Mixed Race0.00.000042See
AUSAustralia Yuendumu Aborigine0.0000191See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
SGPSingapore Chinese0.00.0000149See
ZAFSouth Africa Natal Zulu0.00.0000100See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
PRTPortugal South0.000049See
PHLPhilippines Ivatan0.00.000050See
PRTAzores Central Islands0.000059See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
NCLNew Caledonia0.000065See
MARMorocco Nador Metalsa pop 20.000073See
MARMorocco Settat Chaouya0.00.000098See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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