Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 261 time(s) and present in 166 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
GHAGhana Ga-Adangbe16.80.0916131See
ZAFSouth Africa Natal Zulu16.00.0850100See
ZWEZimbabwe Harare Shona0.0840230See
STPSao Tome Island Forro0.076066See
ZAFSouth Africa Worcester13.00.0690159See
CIVIvory Coast Adiopodoume Akan0.057044See
UGAUganda Kampala pop 20.0510175See
ZMBZambia Lusaka0.046044See
KENKenya, Nyanza Province, Luo tribe9.00.0450100See
GNBGuinea Bissau0.038065See
CMRCameroon Sawa0.038013See
USAUSA NMDP Caribean Black0.037833328See
TZATanzania Maasai7.20.0374336See
USAUSA NMDP African0.036128557See
KENKenya Luo0.0360265See
USAUSA NMDP African American pop 20.0346416581See
USAUSA African American Bethesda6.40.0320187See
SENSenegal Niokholo Mandenka0.0320165See
STPSao Tome Island Angolar0.031032See
USAUSA African American pop 40.03032411See
CMRCameroon Beti0.0280174See
USAUSA African American pop 30.0270564See
MEXMexico Jalisco, Tlaquepaque0.025639See
UGAUganda Kampala0.0250161See
USAUSA African American0.0240252See
MEXMexico Mestizo4.90.024041See
MLIMali Bandiagara0.0220138See
TUNTunisia Gabes0.021095See
MEXMexico Baja California, Tijuana0.020025See
MEXMexico Veracruz, Coatzacoalcos0.017955See
KENKenya Nandi0.0170240See
BRABrazil Belo Horizonte Caucasian3.20.016095See
MARMorocco Atlantic Coast Chaouya0.014098See
MARMorocco Settat Chaouya2.80.014098See
CMRCameroon Bamileke0.013077See
CUBCuba Mixed Race2.40.012042See
NICNicaragua Managua2.40.0120339See
CMRCameroon Yaounde0.011092See
USAUSA NMDP Caribean Indian0.011014339See
USAUSA NMDP Caribean Hispanic0.0105115374See
MEXMexico Nayarit, Tepic0.010397See
MEXMexico Baja Californa, Mexicali0.0100100See
BRABrazil Puyanawa2.00.0100150See
IRNIran Baloch0.0100100See
SDNSudan Mixed2.00.0100200See
MEXMexico Zacatecas, Fresnillo0.0095103See
MEXMexico Durango Rural0.0092326See
BRABrazil Terena1.70.009060See
CPVCape Verde Northwestern Islands0.008062See
IRNIran Gorgan0.008064See
AREUnited Arab Emirates pop 21.60.0080373See
USAUSA North American Native0.0080187See
MEXMexico Tamaulipas Rural0.0079125See
MEXMexico Sonora Rural0.0076197See
MEXMexico Michoacan Rural0.0072348See
MEXMexico Guerrero state0.0069144See
MEXMexico Mexico City Center0.0065152See
COLColombia Bogotá Cord Blood1.30.00651463See
MEXMexico Hidalgo Rural0.006281See
USAUSA Caucasian pop 20.0060265See
MEXMexico Jalisco, Zapopan0.0060168See
USAUSA NMDP Hispanic South or Central American0.0055146714See
SAUSaudi Arabia pop 6 (G)0.005528927See
IRNIran Tabriz Azeris0.005297See
MEXMexico Sonora, Hermosillo0.005199See
MEXMexico Jalisco Rural0.0051585See
MEXMexico Mixtec0.005097See
MEXMexico Puebla Mestizo0.005099See
MEXMexico Oaxaca Jamiltepec Mixtec0.005096See
MEXMexico Guadalajara Mestizo pop 20.0050103See
ARMArmenia combined Regions0.0050100See
ZAFSouth Africa Caucasians0.0050102See
USAUSA Mexican American Mestizo0.0050553See
USAUSA Hispanic pop 20.00481999See
MEXMexico Veracruz Rural0.0046539See
MEXMexico Coahuila Rural0.0046216See
ISRIsrael Ethiopia Jews0.00435928See
ECUEcuador Coast Mixed Ancestry0.0042238See
MEXMexico Chihuahua Rural0.0042236See
MEXMexico Oaxaca Rural0.0041485See
USAUSA Caucasian Bethesda0.80.0040307See
USAUSA Philadelphia Caucasian0.70.0040141See
USAUSA South Texas Hispanic0.0040194See
USAUSA Hispanic0.0040234See
MEXMexico Zacatecas Rural0.0037266See
CHNChina Beijing pop 20.0037826See
MEXMexico Mexico City Mestizo population0.0035143See
MEXMexico Sonora, Ciudad Obregón0.0035143See
MEXMexico Michoacan, Morelia0.0033150See
MEXMexico Mexico City Metropolitan Area Rural0.0033150See
CHESwitzerland Graubunden0.0030759See
USAUSA San Diego0.60.0030496See
IDNIndonesia Sundanese and Javanese0.0030201See
JORJordan Amman0.0030146See
MEXMexico Veracruz, Veracruz city0.0029171See
MEXMexico Veracruz, Xalapa0.0027187See
MEXMexico Yucatan, Merida0.0026192See
USAUSA NMDP Mexican or Chicano0.0024261235See
MEXMexico Nuevo Leon, Monterrey city0.0022226See
MEXMexico Mexico City Mestizo pop 20.0021234See
ITAItaly pop 50.0020975See
USAUSA NMDP American Indian South or Central America0.00205926See
USAUSA Eastern European0.0020558See
SAUSaudi Arabia Guraiat and Hail0.50.0020213See
USAUSA Caucasian pop 40.00191070See
MYSMalaysia Peninsular Indian0.40.0018271See
USAUSA NMDP Vietnamese0.001643540See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.30.00134335See
MEXMexico Puebla, Puebla city0.00131994See
MEXMexico Coahuila, Torreon0.0013396See
USAUSA NMDP North American Amerindian0.001335791See
ECUEcuador Mixed Ancestry0.00131173See
DEUGermany DKMS - Portugal minority0.00131176See
ISRIsrael Morocco Jews0.001136718See
USAUSA NMDP Middle Eastern or North Coast of Africa0.001170890See
USAUSA NMDP Alaska Native or Aleut0.00101376See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
NIRIreland Northern0.10.00101000See
CHNChina Beijing Shijiazhuang Tianjian Han0.0010618See
HRVCroatia pop 40.00094000See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000946682See
USAUSA Asian pop 20.00091772See
DEUGermany DKMS - Italy minority0.00091159See
MEXMexico Jalisco, Guadalajara city0.00081189See
INDIndia West UCBB0.20.00085829See
DEUGermany DKMS - Netherlands minority0.00071374See
MEXMexico Mexico City North0.0007751See
ECUEcuador Andes Mixed Ancestry0.0006824See
INDIndia Tamil Nadu0.00062492See
MEXMexico Tlaxcala Rural0.0006830See
ISRIsrael Arab pop 20.000512301See
USAUSA NMDP Hawaiian or other Pacific Islander0.000511499See
MYSMalaysia Peninsular Malay0.10.0005951See
DEUGermany DKMS - Croatia minority0.00052057See
DEUGermany DKMS - Spain minority0.00051107See
DEUGermany DKMS - United Kingdom minority0.00051043See
USAUSA NMDP European Caucasian0.00041242890See
DEUGermany pop 60.00048862See
DEUGermany DKMS - Austria minority0.00031698See
HKGHong Kong Chinese cord blood registry0.00033892See
ISRIsrael USA Jews0.00026058See
USAUSA NMDP Filipino0.000250614See
USAUSA NMDP South Asian Indian0.0002185391See
USAUSA NMDP Southeast Asian0.000227978See
DEUGermany pop 80.000239689See
DEUGermany DKMS - Greece minority0.00031894See
CHNChina Jiangsu Han0.00023238See
HKGHong Kong Chinese BMDR0.00027595See
USAUSA NMDP Japanese0.000224582See
INDIndia South UCBB0.00.000211446See
ISRIsrael Iraq Jews0.000213270See
DEUGermany DKMS - German donors0.00013456066See
USAUSA NMDP Chinese0.000199672See
USAUSA NMDP Korean0.000177584See
DEUGermany DKMS - Turkey minority0.00014856See
INDIndia North UCBB0.00.00015849See
ISRIsrael Iran Jews0.00018153See
ISRIsrael Tunisia Jews0.00019070See
ISRIsrael YemenJews0.000015542See
INDIndia Mumbai Maratha0.000091See
IDNIndonesia Java pop 20.000036See
HKGHong Kong Chinese0.00.0000569See
KORSouth Korea pop 30.0000485See
ECUEcuador Amazonia Mixed Ancestry0.000039See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
CHNChina North Han0.0000105See
CHNChina Tibet Region Tibetan0.0000158See
CPVCape Verde Southeastern Islands0.000062See
CMRCameroon Baka Pygmy0.000010See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
MEXMexico Mexico City East0.000079See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Mexico City South0.000052See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Mexico City West0.000033See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Tabasco, Villahermosa0.000082See
MEXMexico Morelos, Cuernavaca0.000082See
MEXMexico Oaxaca, Oaxaca city0.0000151See
MEXMexico Colima, Colima city0.000061See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Veracruz, Cordoba0.000056See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Aguascalientes state0.000095See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Coahuila, Saltillo0.000072See
MEXMexico Durango, Durango city0.0000153See
MEXMexico Chihuahua, Ciudad Juarez0.0000106See
MEXMexico Chihuahua Chihuahua City0.0000119See
MEXMexico Sinaloa, Culiacán0.0000103See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Nayarit Rural0.000064See
MEXMexico Sinaloa Mestizo0.000056See
MEXMexico Baja California Rural0.000050See
MEXMexico Mexico City Mestizo0.0000121See
MEXMexico Sinaloa Rural0.0000183See
MEXMexico Guanajuato Rural0.0000162See
MEXMexico Colima Rural0.000043See
MEXMexico Nuevo Leon Rural0.0000439See
MEXMexico Queretaro Rural0.000043See
USAUSA Alaska Yupik0.0000252See
USAUSA Asian0.0000358See
USAUSA San Antonio Caucasian0.0000222See
MEXMexico Puebla Rural0.0000833See
MEXMexico Morelos Rural0.000030See
MEXMexico Tabasco Rural0.0000142See
MEXMexico Chiapas Rural0.0000121See
MEXMexico Campeche Rural0.000047See
MEXMexico Yucatan Rural0.0000132See
MEXMexico Quintana Roo Rural0.000050See
MEXMexico San Luis Potosi Rural0.000087See
MARMorocco Nador Metalsa pop 20.000073See
NLDNetherlands Leiden0.00001305See
PHLPhilippines Ivatan0.00.000050See
POLPoland DKMS0.000120653See
SGPSingapore Chinese0.00.0000149See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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