Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 181 time(s) and present in 139 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
GNBGuinea Bissau Bijago0.196023See
GNBGuinea Bissau Papel0.160025See
KENKenya, Nyanza Province, Luo tribe18.00.0950100See
UGAUganda Kampala pop 20.0940175See
GNBGuinea Bissau Balanta0.094048See
CRICosta Rica African -Caribbean (G)16.60.0880102See
CMRCameroon Beti0.0830174See
GNBGuinea Bissau0.077065See
KENKenya Luo0.0720265See
BFABurkina Faso Mossi0.066053See
STPSao Tome Island Angolar0.063032See
USAUSA NMDP African0.056728557See
CPVCape Verde Southeastern Islands0.056062See
USAUSA NMDP Caribean Black0.055833328See
USAUSA NMDP African American pop 20.0546416581See
GHAGhana Ga-Adangbe10.70.0534131See
USAUSA African American pop 40.05222411See
UGAUganda Kampala0.0520161See
USAUSA African American pop 30.0510564See
USAUSA African American Bethesda10.00.0500187See
CMRCameroon Yaounde0.050092See
CMRCameroon Bamileke0.045077See
TZATanzania Maasai8.70.0433336See
USAUSA African American0.0400252See
AREUnited Arab Emirates Abu Dhabi0.038552See
CMRCameroon Sawa0.038013See
MLIMali Bandiagara0.0360138See
MYSMalaysia Champa6.90.034029See
ZAFSouth Africa Worcester6.00.0310159See
STPSao Tome Island Forro0.030066See
IRNIran Baloch0.0280100See
ZWEZimbabwe Harare Shona0.0270230See
USAUSA African American pop 20.0270149See
ZMBZambia Lusaka0.023044See
SENSenegal Niokholo Mandenka0.0220165See
BFABurkina Faso Rimaibe0.021047See
ISRIsrael Ethiopia Jews0.02015928See
MYSMalaysia Kelantan3.60.018028See
USAUSA NMDP Caribean Indian0.018014339See
KENKenya Nandi0.0170240See
USAUSA Spain Ancestry0.0160279See
AREUnited Arab Emirates Pop 10.0150570See
BRABrazil Mixed0.0150108See
MARMorocco Nador Metalsa pop 20.014073See
USAUSA NMDP Caribean Hispanic0.0136115374See
SGPSingapore SGVP Malay MAS0.012089See
THAThailand Northeast0.012066See
MEXMexico Veracruz Xalapa2.40.011984See
VENVenezuela Colonia Tovar0.011686See
USAUSA Caucasian Bethesda2.20.0110307See
COLColombia North Chimila Amerindians0.010647See
TUNTunisia Gabes0.010595See
NICNicaragua Mestizo (G)2.00.0100155See
BRABrazil Puyanawa2.00.0100150See
BFABurkina Faso Fulani0.010049See
COLColombia North Wiwa El Encanto0.009652See
CRICosta Rica Guanacaste Mestizo (G)1.80.0090110See
NICNicaragua Managua1.50.0090339See
USAUSA Hispanic pop 20.00751999See
USAUSA NMDP Hispanic South or Central American0.0073146714See
MARMorocco Atlantic Coast Chaouya0.007098See
JORJordan Amman0.0070146See
MARMorocco Settat Chaouya1.40.007098See
MYSMalaysia Peninsular Malay1.40.0068951See
CHNChina Canton Han0.0060264See
COLColombia Bogotá Cord Blood1.10.00581463See
MEXMexico Chihuahua Chihuahua City Pop 21.10.005788See
USAUSA San Diego1.00.0050496See
SAUSaudi Arabia Guraiat and Hail0.90.0050213See
SDNSudan Mixed0.50.0050200See
CHNChina South Han0.0050284See
USAUSA Mexican American Mestizo0.0050553See
USAUSA NMDP Mexican or Chicano0.0044261235See
USAUSA Hispanic0.0040234See
LBYLibya Cyrenaica0.0040118See
SGPSingapore Riau Malay0.0040132See
MEXMexico Mexico City Mestizo population0.0035143See
MEXMexico Mexico City Tlalpan0.60.0030330See
IDNIndonesia Sundanese and Javanese0.0030201See
USAUSA NMDP American Indian South or Central America0.00305926See
VNMVietnam Hanoi Kinh pop 20.0030170See
USAUSA NMDP Vietnamese0.002843540See
USAUSA NMDP Southeast Asian0.002427978See
USAUSA NMDP North American Amerindian0.002335791See
HKGHong Kong Chinese BMDR0.00237595See
MEXMexico Mexico City Mestizo pop 20.0021234See
TWNTaiwan Han Chinese0.0020504See
CHNChina Beijing Shijiazhuang Tianjian Han0.0020618See
CRICosta Rica Central Valley Mestizo (G)0.40.0020221See
USAUSA NMDP South Asian Indian0.0015185391See
USAUSA NMDP Hawaiian or other Pacific Islander0.001411499See
INDIndia Kerala Malayalam speaking0.30.0014356See
USAUSA NMDP Chinese0.001499672See
ISRIsrael Morocco Jews0.001436718See
ISRIsrael Arab pop 20.001312301See
DEUGermany DKMS - Spain minority0.00141107See
HKGHong Kong Chinese cord blood registry0.00133892See
ISRIsrael Argentina Jews0.00134307See
DEUGermany DKMS - France minority0.00111406See
USAUSA Asian pop 20.00111772See
USAUSA NMDP Middle Eastern or North Coast of Africa0.001170890See
NLDNetherlands Leiden0.00101305See
ITAItaly pop 50.0010975See
USAUSA Eastern European0.0010558See
USAUSA NMDP Alaska Native or Aleut0.00101376See
USAUSA Caucasian pop 40.00091070See
DEUGermany DKMS - Portugal minority0.00091176See
DEUGermany DKMS - Italy minority0.00091159See
DEUGermany DKMS - Netherlands minority0.00071374See
ISRIsrael USA Jews0.00076058See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.10.00064335See
USAUSA NMDP Filipino0.000550614See
DEUGermany DKMS - Greece minority0.00051894See
ISRIsrael Georgia Jews0.00044471See
USAUSA NMDP European Caucasian0.00041242890See
DEUGermany DKMS - Romania minority0.00041234See
INDIndia North UCBB0.10.00035849See
ISRIsrael Tunisia Jews0.00039070See
ISRIsrael YemenJews0.000315542See
DEUGermany DKMS - Austria minority0.00031698See
DEUGermany DKMS - China minority0.00041282See
INDIndia Central UCBB0.10.00024204See
INDIndia East UCBB0.00.00022403See
DEUGermany DKMS - Turkey minority0.00024856See
INDIndia West UCBB0.00.00025829See
ISRIsrael Iraq Jews0.000213270See
DEUGermany DKMS - German donors0.00013456066See
DEUGermany pop 80.000139689See
DEUGermany pop 60.00018862See
HRVCroatia pop 40.00014000See
USAUSA NMDP Japanese0.000124582See
ISRIsrael USSR Jews0.000145681See
USAUSA NMDP Korean0.000077584See
ISRIsrael Ashkenazi Jews pop 30.00004625See
ISRIsrael Poland Jews0.000013871See
ITAItaly Sardinia pop30.0000100See
IDNIndonesia Java pop 20.000036See
GNBGuinea Bissau Fula0.000031See
ESPSpain Gipuzkoa Basque0.0000100See
ESPSpain Catalonia Girona0.000088See
ESPSpain Majorca and Minorca0.000090See
FRAFrance Corsica Island0.0000100See
CZECzech Republic0.0000106See
CMRCameroon Baka Pygmy0.000010See
CHNChina Tibet Region Tibetan0.0000158See
CPVCape Verde Northwestern Islands0.000062See
CHNChina North Han0.0000105See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
USAUSA North American Native0.0000187See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
USAUSA San Antonio Caucasian0.0000222See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian pop 20.0000265See
PHLPhilippines Ivatan0.00.000050See
SGPSingapore SGVP Chinese CHS0.000096See
SGPSingapore SGVP. Indian INS0.000086See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
KORSouth Korea pop 30.0000485See
USAUSA Asian0.0000358See
ZAFSouth Africa Caucasians0.0000102See
VENVenezuela Caracas Mestizo0.000050See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA Caucasian pop 30.000088See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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