Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 123 time(s) and present in 58 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
USAUSA Spain Ancestry0.0500279See
USAUSA African American Bethesda4.00.0200187See
CRICosta Rica African -Caribbean (G)4.00.0200102See
STPSao Tome Island Angolar0.016032See
KENKenya, Nyanza Province, Luo tribe2.00.0150100See
ZAFSouth Africa Natal Zulu3.00.0150100See
USAUSA African American0.0120252See
CUBCuba Mixed Race2.40.012042See
CMRCameroon Yaounde0.011092See
USAUSA NMDP African0.009428557See
USAUSA NMDP Caribean Black0.009433328See
KENKenya Luo0.0090265See
CMRCameroon Beti0.0090174See
USAUSA NMDP African American pop 20.0089416581See
STPSao Tome Island Forro0.008066See
USAUSA African American pop 40.00792411See
USAUSA African American pop 30.0070564See
CUBCuba Caucasian1.40.007070See
CMRCameroon Bamileke0.006077See
UGAUganda Kampala pop 20.0060175See
SENSenegal Niokholo Mandenka0.0050165See
USAUSA Philadelphia Caucasian0.70.0040141See
KENKenya Nandi0.0040240See
ZAFSouth African Black0.70.0035142See
USAUSA North American Native0.0030187See
BRABrazil Rio de Janeiro Parda0.0029170See
COLColombia Bogotá Cord Blood0.40.00211463See
CRICosta Rica Central Valley Mestizo (G)0.40.0020221See
ZWEZimbabwe Harare Shona0.0020230See
USAUSA NMDP Caribean Indian0.002014339See
USAUSA NMDP Caribean Hispanic0.0017115374See
USAUSA Hispanic pop 20.00101999See
USAUSA Mexican American Mestizo0.0010553See
USAUSA Asian0.0010358See
USAUSA NMDP Hispanic South or Central American0.0008146714See
DEUGermany DKMS - Portugal minority0.00041176See
CHESwitzerland Graubunden0.0004759See
ISRIsrael Arab pop 20.000312301See
USAUSA NMDP Mexican or Chicano0.0003261235See
USAUSA NMDP North American Amerindian0.000235791See
DEUGermany DKMS - Croatia minority0.00022057See
USAUSA NMDP Hawaiian or other Pacific Islander0.000211499See
ISRIsrael Ethiopia Jews0.00025928See
USAUSA NMDP Filipino0.000250614See
HRVCroatia pop 40.00014000See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.00.00014335See
SAUSaudi Arabia pop 6 (G)0.000128927See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000070890See
USAUSA NMDP European Caucasian0.00001242890See
ISRIsrael Morocco Jews0.000036718See
DEUGermany DKMS - German donors0.00003456066See
USAUSA NMDP South Asian Indian0.0000185391See
USAUSA NMDP Vietnamese0.000043540See
USAUSA NMDP Korean0.000077584See
USAUSA NMDP Chinese0.000099672See
USAUSA Asian pop 20.00001772See
SGPSingapore Chinese0.00.0000149See
USAUSA Hispanic0.0000234See
SDNSudan Mixed0.00.0000200See
PHLPhilippines Ivatan0.00.000050See
USAUSA Caucasian0.00.000061655See
USAUSA San Antonio Caucasian0.0000222See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian pop 20.0000265See
USAUSA Caucasian Bethesda0.00.0000307See
ZMBZambia Lusaka0.000044See
ZAFSouth Africa Caucasians0.0000102See
FRAFrance Rennes pop 30.0000200See
HKGHong Kong Chinese0.00.0000569See
DEUGermany pop 80.000039689See
CZECzech Republic0.0000106See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
CHNChina North Han0.0000105See
CHNChina Tibet Region Tibetan0.0000158See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
BRABrazil Belo Horizonte Caucasian0.00.000095See
ITAItaly Bergamo0.00.0000101See
KORSouth Korea pop 30.0000485See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
MLIMali Bandiagara0.0000138See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
PAKPakistan Karachi Parsi0.000091See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
UGAUganda Kampala0.0000161See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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