Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 172 time(s) and present in 124 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
GNBGuinea Bissau Balanta0.094048See
TUNTunisia Ghannouch0.055082See
ZAFSouth Africa Natal Zulu11.00.0550100See
GNBGuinea Bissau0.054065See
KENKenya Nandi0.0500240See
TUNTunisia Gabes0.047395See
STPSao Tome Island Angolar0.047032See
USAUSA African American0.0400252See
USAUSA African American pop 30.0400564See
STPSao Tome Island Forro0.038066See
MLIMali Bandiagara0.0360138See
USAUSA NMDP Caribean Black0.035633328See
USAUSA NMDP African American pop 20.0335416581See
USAUSA African American pop 40.03352411See
ZWEZimbabwe Harare Shona0.0330230See
GNBGuinea Bissau Fula0.032031See
CMRCameroon Beti0.0320174See
USAUSA NMDP African0.031428557See
USAUSA African American Bethesda6.00.0300187See
UGAUganda Kampala0.0280161See
TUNTunisia pop 30.0280104See
USAUSA African American pop 20.0270149See
GHAGhana Ga-Adangbe5.30.0267131See
KENKenya Luo0.0260265See
CMRCameroon Bamileke0.026077See
BRABrazil Mixed0.0250108See
KENKenya, Nyanza Province, Luo tribe5.00.0250100See
ZAFSouth Africa Worcester4.00.0250159See
CUBCuba Mixed Race4.80.024042See
CMRCameroon Yaounde0.022092See
GNBGuinea Bissau Bijago0.022023See
SENSenegal Niokholo Mandenka0.0220165See
MARMorocco Nador Metalsa pop 20.021073See
BRABrazil Belo Horizonte Caucasian4.20.021095See
GNBGuinea Bissau Papel0.020025See
UGAUganda Kampala pop 20.0200175See
ZAFSouth Africa Caucasians0.0200102See
TZATanzania Maasai3.30.0164336See
MARMorocco Atlantic Coast Chaouya0.014098See
MARMorocco Settat Chaouya2.80.014098See
ZMBZambia Lusaka0.012044See
ISRIsrael Libya Jews0.01103739See
SDNSudan Mixed2.00.0100200See
USAUSA NMDP Caribean Indian0.009014339See
USAUSA NMDP Caribean Hispanic0.0084115374See
CPVCape Verde Southeastern Islands0.008062See
CUBCuba Caucasian1.40.007070See
SAUSaudi Arabia Guraiat and Hail1.40.0070213See
MEXMexico Mexico City Mestizo population0.0070143See
USAUSA Hispanic0.0060234See
ISRIsrael Ethiopia Jews0.00555928See
IRNIran Tabriz Azeris0.005297See
ISRIsrael Tunisia Jews0.00529070See
ISRIsrael Arab Druze0.0050101See
USAUSA NMDP Hispanic South or Central American0.0046146714See
FRAFrance Southeast0.80.0040130See
USAUSA NMDP American Indian South or Central America0.00405926See
USAUSA Spain Ancestry0.0040279See
SAUSaudi Arabia pop 6 (G)0.003728927See
DEUGermany DKMS - Spain minority0.00361107See
DEUGermany DKMS - Austria minority0.00321698See
USAUSA Hispanic pop 20.00331999See
USAUSA North American Native0.0030187See
BRABrazil Puyanawa0.70.0030150See
JORJordan Amman0.0030146See
USAUSA San Diego0.60.0030496See
NICNicaragua Managua0.60.0030339See
DEUGermany DKMS - Portugal minority0.00301176See
ISRIsrael Arab pop 20.002812301See
COLColombia Bogotá Cord Blood0.50.00271463See
USAUSA NMDP Mexican or Chicano0.0025261235See
MEXMexico Mexico City Mestizo pop 20.0021234See
DEUGermany DKMS - France minority0.00211406See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.40.00214335See
ISRIsrael Morocco Jews0.002036718See
IRLIreland South0.40.0020250See
AREUnited Arab Emirates Pop 10.0020570See
NLDNetherlands Leiden0.00201305See
USAUSA Caucasian pop 20.0020265See
USAUSA NMDP Alaska Native or Aleut0.00201376See
USAUSA NMDP North American Amerindian0.001935791See
DEUGermany DKMS - Romania minority0.00161234See
USAUSA NMDP Middle Eastern or North Coast of Africa0.001270890See
USAUSA NMDP Filipino0.001150614See
USAUSA NMDP Hawaiian or other Pacific Islander0.001011499See
USAUSA Caucasian0.20.001061655See
NIRIreland Northern0.10.00101000See
ENGEngland Lancaster0.20.0010545See
ITAItaly pop 50.0010975See
USAUSA Mexican American Mestizo0.0010553See
USAUSA Eastern European0.0010558See
USAUSA NMDP European Caucasian0.00091242890See
DEUGermany DKMS - United Kingdom minority0.00101043See
ISRIsrael Druze0.00085914See
ISRIsrael Argentina Jews0.00084307See
POLPoland DKMS0.000720653See
CZECzech Republic NMDR0.00065099See
DEUGermany pop 80.000539689See
ENGEngland Manchester0.10.00051640See
RUSRussia Karelia0.00051075See
DEUGermany DKMS - German donors0.00043456066See
DEUGermany DKMS - Italy minority0.00041159See
HRVCroatia pop 40.00044000See
ISRIsrael USA Jews0.00036058See
ISRIsrael Ashkenazi Jews pop 30.00034625See
ISRIsrael Poland Jews0.000313871See
DEUGermany pop 60.00038862See
DEUGermany DKMS - Greece minority0.00031894See
DEUGermany DKMS - Turkey minority0.00024856See
USAUSA Asian pop 20.00031772See
ISRIsrael Iraq Jews0.000213270See
USAUSA NMDP Southeast Asian0.000227978See
ISRIsrael USSR Jews0.000145681See
USAUSA NMDP South Asian Indian0.0000185391See
USAUSA NMDP Vietnamese0.000043540See
USAUSA NMDP Chinese0.000099672See
USAUSA NMDP Korean0.000077584See
SCOScotland Orkney0.00.000099See
SGPSingapore Chinese0.00.0000149See
USAUSA San Antonio Caucasian0.0000222See
USAUSA Alaska Yupik0.0000252See
PHLPhilippines Ivatan0.00.000050See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
PAKPakistan Karachi Parsi0.000091See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
HKGHong Kong Chinese0.00.0000569See
MEXMexico Mestizo0.00.000041See
KORSouth Korea pop 30.0000485See
ESPSpain Gipuzkoa Basque0.0000100See
ESPSpain Catalonia Girona0.000088See
FRAFrance Rennes pop 30.0000200See
CHNChina North Han0.0000105See
CHNChina Tibet Region Tibetan0.0000158See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CPVCape Verde Northwestern Islands0.000062See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CZECzech Republic0.0000106See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA Caucasian pop 40.00001070See
USAUSA Asian0.0000358See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA Caucasian pop 30.000088See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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