Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 95 time(s) and present in 59 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CRICosta Rica Cabecar NA-DHS_9 (G)78.90.500019See
CRICosta Rica Amerindians (G)58.30.3610125See
COLColombia Arhuaco NA-DHS_16 (G)47.10.235317See
COLColombia Kogi NA-DHS_17 (G)42.90.214315See
CRICosta Rica Guaymi NA-DHS_10 (G)33.30.166718See
COLColombia Wayuu NA-DHS_15 (G)21.40.142915See
MEXMexico Chichen Itza Maya (prehispanic)0.106447See
CRICosta Rica Central Valley Mestizo (G)16.70.0950221See
NICNicaragua Mestizo (G)17.40.0900155See
COLColombia Zenu NA-DHS_18 (G)16.70.083316See
NICNicaragua Managua13.20.0733339See
CRICosta Rica Guanacaste Mestizo (G)11.80.0590110See
MEXMexico Oaxaca Mixtec0.0500103See
COLColombia Bogotá Cord Blood7.40.03831463See
MEXMexico Oaxaca Mixe0.038055See
MEXMexico Tixcacaltuyub Maya0.037367See
MEXMexico Mexico City Mestizo pop 20.0342234See
RUSRussia Tuva pop 20.0320169See
GTMGuatemala Kaqchikel NA-DHS_8 (G)5.30.026319See
MEXMexico Mixe NA-DHS_6 (G)5.00.025020See
MEXMexico Mixtec NA-DHS_5 (G)5.00.025020See
USAUSA NMDP Hispanic South or Central American0.0197146714See
MEXMexico Chiapas Lacandon Mayans0.0183218See
USAUSA NMDP Caribean Hispanic0.0172115374See
USAUSA Spain Ancestry0.0140279See
USAUSA South Texas Hispanic0.0130194See
USAUSA Alaska Yupik0.0130252See
USAUSA Hispanic pop 20.01201999See
USAUSA NMDP Caribean Indian0.012014339See
GHAGhana Ga-Adangbe1.50.0115131See
INDIndia New Delhi0.009071See
CHESwitzerland Lugano0.00741169See
USAUSA NMDP Mexican or Chicano0.0072261235See
USAUSA Mexican American Mestizo0.0060553See
MYSMalaysia Peninsular Chinese1.00.0052194See
CRICosta Rica African -Caribbean (G)1.00.0050102See
CHESwitzerland Geneva pop 20.00451267See
USAUSA NMDP American Indian South or Central America0.00405926See
USAUSA San Antonio Caucasian0.0030222See
UGAUganda Kampala0.0030161See
USAUSA Hispanic0.0020234See
CHESwitzerland Lausanne0.0015993See
USAUSA NMDP Caribean Black0.000833328See
MYSMalaysia Peninsular Malay0.10.0005951See
DEUGermany DKMS - Spain minority0.00051107See
USAUSA African American pop 40.00042411See
USAUSA Arizona Gila River Pima0.00033000See
DEUGermany DKMS - Netherlands minority0.00041374See
USAUSA NMDP Hawaiian or other Pacific Islander0.000111499See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000170890See
INDIndia North UCBB0.00.00015849See
USAUSA NMDP Filipino0.000150614See
USAUSA NMDP North American Amerindian0.000135791See
USAUSA NMDP African American pop 20.0000416581See
USAUSA NMDP Vietnamese0.000043540See
USAUSA NMDP Korean0.000077584See
USAUSA NMDP European Caucasian0.00001242890See
DEUGermany DKMS - German donors0.00003456066See
NLDNetherlands Leiden0.00001305See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
CHESwitzerland Basel0.00001888See
USAUSA Asian pop 20.00001772See
CHNChina Tibet Region Tibetan0.0000158See
LBNLebanon Mixed0.000097See
ZMBZambia Lusaka0.000044See
MARMorocco Nador Metalsa pop 20.000073See
FRAFrance West0.00.0000100See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
KORSouth Korea pop 30.0000485See
USAUSA Philadelphia Caucasian0.00.0000141See
CHNChina North Han0.0000105See
USAUSA North American Native0.0000187See
USAUSA Asian0.0000358See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
MLIMali Bandiagara0.0000138See
CZECzech Republic0.0000106See
MARMorocco Settat Chaouya0.00.000098See
USAUSA Caucasian pop 20.0000265See
USAUSA African American0.0000252See
RUSRussia Nenet Mixed0.000055See
RUSRussia Arkhangelsk Pomor0.000063See
RUSRussia Murmansk Saomi Mixed0.000070See
IRNIran Tehran0.0000120See
ITAItaly Bergamo0.00.0000101See
NIRIreland Northern0.00.00001000See
MEXMexico Oaxaca Zapotec0.000090See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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