Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 142 time(s) and present in 111 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
PNGPapua New Guinea Karimui Plateau Pawaia0.225080See
TWNTaiwan Pazeh21.80.109055See
PNGPapua New Guinea West Schrader Ranges Haruai0.091055See
TWNTaiwan Puyuma18.00.090050See
PNGPapua New Guinea Wosera Abelam0.0800131See
TWNTaiwan Atayal15.10.0800106See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.071057See
CHNChina Tibet Region Tibetan0.0700158See
TWNTaiwan Siraya11.80.069051See
PNGPapua New Guinea Madang0.055065See
BGRBulgaria Romani0.045013See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0429233See
NCLNew Caledonia0.039065See
PNGPapua New Guinea Wanigela Keapara0.038066See
TWNTaiwan Tzu Chi Cord Blood Bank0.0350710See
CHNChina Yunnan Province Han0.0350101See
TWNTaiwan Tzu Chi Morrow Donor Registry0.034046682See
TWNTaiwan pop 30.0310212See
TWNTaiwan Tao6.00.030050See
TWNTaiwan Tsou3.90.029051See
CHNChina Guangxi Region Maonan0.0280108See
TWNTaiwan Han Chinese0.0260504See
TWNTaiwan Minnan pop 14.90.0250102See
SGPSingapore Thai0.0250100See
CHNChina Guangzhou0.0250102See
INDIndia Mumbai Maratha0.025091See
CHNChina Southwest Dai0.0240124See
HKGHong Kong Chinese cord blood registry0.02303892See
HKGHong Kong Chinese BMDR0.02057595See
INDIndia West Bhil0.020050See
THAThailand pop 30.020049See
USAUSA NMDP Chinese0.019199672See
HKGHong Kong Chinese3.70.0190569See
CHNChina Qinghai Province Hui0.0180110See
MYSMalaysia Champa3.50.017029See
SGPSingapore Chinese Han0.017094See
MYSMalaysia Peninsular Chinese3.10.0155194See
CHNChina Inner Mongolia Region0.0150102See
TWNTaiwan pop 20.0150364See
CHNChina Canton Han0.0130264See
DEUGermany DKMS - China minority0.01291282See
CHNChina Jiangsu Province Han0.0123334See
CHNChina South Han0.0120284See
USAUSA NMDP Vietnamese0.011343540See
SGPSingapore SGVP Chinese CHS0.011096See
NZLNew Zealand Maori with Full Ancestry2.20.011046See
INDIndia Khandesh Region Pawra0.010050See
CHNChina Jiangsu Han0.01003238See
CHNChina Guangdong Province Meizhou Han0.0100100See
SGPSingapore Riau Malay0.0100132See
SGPSingapore Chinese2.00.0100149See
PHLPhilippines Ivatan2.00.010050See
TWNTaiwan Ami2.00.010098See
CHNChina Hubei Han2.00.00983732See
AREUnited Arab Emirates Abu Dhabi0.009652See
TWNTaiwan Hakka1.80.009055See
TWNTaiwan Taroko1.80.009055See
CHNChina Beijing0.008067See
USAUSA Asian pop 20.00711772See
USAUSA NMDP Filipino0.006650614See
USAUSA NMDP Hawaiian or other Pacific Islander0.006011499See
SGPSingapore SGVP. Indian INS0.006086See
SGPSingapore SGVP Malay MAS0.006089See
CHNChina Marrow Donor Registry0.0060600See
USAUSA NMDP Southeast Asian0.005527978See
ESPSpain Andalusia Romani0.005099See
CHNChina North Han0.0050105See
CHNChina Beijing Shijiazhuang Tianjian Han0.0050618See
NZLNew Zealand Maori with Admixed History1.00.0050105See
MYSMalaysia Peninsular Malay0.80.0042951See
AUSAustralia New South Wales Caucasian0.0040134See
CHNChina Yunnan Province Wa0.0040119See
MYSMalaysia Peninsular Indian0.70.0037271See
INDIndia Central UCBB0.70.00364204See
INDIndia North UCBB0.70.00335849See
JPNJapan Central0.0030371See
USAUSA Asian0.0030358See
RUSRussia Tuva pop 20.0030169See
INDIndia West UCBB0.50.00245829See
USAUSA NMDP Korean0.002377584See
USAUSA NMDP Japanese0.002024582See
USAUSA San Diego0.30.0020496See
SAUSaudi Arabia Guraiat and Hail0.50.0020213See
JPNJapan pop 30.00201018See
USAUSA NMDP South Asian Indian0.0020185391See
JPNJapan pop 160.001918604See
INDIndia South UCBB0.30.001711446See
KORSouth Korea pop 100.00134128See
INDIndia Tamil Nadu0.00122492See
INDIndia East UCBB0.20.00102403See
AREUnited Arab Emirates Pop 10.0010570See
ISRIsrael Iran Jews0.00098153See
ISRIsrael Kavkazi Jews0.00072840See
DEUGermany DKMS - Spain minority0.00051107See
DEUGermany DKMS - Turkey minority0.00034856See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000370890See
USAUSA Hispanic pop 20.00031999See
USAUSA NMDP North American Amerindian0.000135791See
USAUSA NMDP Caribean Black0.000133328See
CZECzech Republic NMDR0.00015099See
ISRIsrael YemenJews0.000115542See
ISRIsrael USSR Jews0.000045681See
USAUSA NMDP Caribean Hispanic0.0000115374See
USAUSA NMDP Hispanic South or Central American0.0000146714See
USAUSA NMDP African American pop 20.0000416581See
DEUGermany DKMS - German donors0.00003456066See
USAUSA NMDP African0.000028557See
USAUSA NMDP European Caucasian0.00001242890See
USAUSA NMDP Mexican or Chicano0.0000261235See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA African American pop 40.00002411See
ZAFSouth Africa Natal Zulu0.00.0000100See
USAUSA North American Native0.0000187See
POLPoland DKMS0.000020653See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian pop 20.0000265See
USAUSA African American0.0000252See
USAUSA Hispanic0.0000234See
CHNChina Yunnan Province Jinuo0.0000109See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
AUSAustralia Yuendumu Aborigine0.0000191See
BRABrazil Belo Horizonte Caucasian0.00.000095See
KORSouth Korea pop 30.0000485See
INDIndia West Coast Parsi0.000050See
ITAItaly Bergamo0.00.0000101See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
PNGPapua New Guinea East New Britain Rabaul0.000060See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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