Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 232 time(s) and present in 95 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ARGArgentina Gran Chaco Mataco Wichi10.90.054049See
COLColombia Inga NA-DHS_11 (G)7.10.035716See
INDIndia Tamil Nadu Nadar0.033061See
CHNChina Beijing pop 20.0257826See
MEXMexico Mestizo4.90.024041See
GEOGeorgia Tibilisi Kurd0.017031See
CHNChina Guangdong Province Meizhou Han0.0150100See
ISRIsrael Bukhara Jews0.01362317See
SGPSingapore SGVP. Indian INS0.013086See
SAUSaudi Arabia pop 52.50.0127158See
SGPSingapore SGVP Chinese CHS0.011096See
INDIndia North pop 20.010072See
CHESwitzerland Luzern0.00971553See
GEOGeorgia Tibilisi0.0090109See
INDIndia New Delhi0.008071See
CHLChile Mapuche0.007766See
SAUSaudi Arabia Guraiat and Hail1.50.0070213See
INDIndia Northeast UCBB1.40.0068296See
GEOGeorgia Svaneti Region Svan0.006080See
USAUSA Hispanic0.0060234See
SAUSaudi Arabia pop 6 (G)0.005928927See
CHNChina North Han0.0050105See
CHNChina Beijing Shijiazhuang Tianjian Han0.0050618See
ARMArmenia combined Regions0.0050100See
INDIndia Delhi pop 21.10.005090See
CHESwitzerland St Gallen0.00482113See
INDIndia Central UCBB0.90.00454204See
INDIndia East UCBB0.90.00442403See
INDIndia North UCBB0.80.00405849See
AUSAustralia New South Wales Caucasian0.0040134See
ARGArgentina Gran Chaco Eastern Toba0.90.0040135See
FRAFrance Southeast0.80.0040130See
USAUSA NMDP South Asian Indian0.0039185391See
MYSMalaysia Peninsular Indian0.70.0037271See
INDIndia South UCBB0.70.003211446See
DEUGermany DKMS - Turkey minority0.00314856See
INDIndia West UCBB0.60.00305829See
USAUSA NMDP Southeast Asian0.003027978See
CHESwitzerland Geneva pop 20.00251267See
ITAItaly pop 50.0020975See
CHESwitzerland Zurich0.00194875See
INDIndia Tamil Nadu0.00162492See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00151028See
USAUSA Asian pop 20.00141772See
USAUSA NMDP Middle Eastern or North Coast of Africa0.001070890See
USAUSA NMDP Caribean Indian0.001014339See
USAUSA Asian0.0010358See
USAUSA African American pop 80.0010605See
TWNTaiwan Han Chinese0.0010504See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
LKASri Lanka Colombo0.10.0010714See
NIRIreland Northern0.10.00101000See
MEXMexico Veracruz Rural0.0009539See
ISRIsrael Arab pop 20.000912301See
DEUGermany DKMS - Romania minority0.00081234See
MEXMexico Mexico City North0.0007751See
DEUGermany DKMS - Croatia minority0.00072057See
ECUEcuador Andes Mixed Ancestry0.0006824See
DEUGermany DKMS - Austria minority0.00061698See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000646682See
USAUSA NMDP Caribean Hispanic0.0006115374See
USAUSA NMDP Hispanic South or Central American0.0005146714See
RUSRussia Karelia0.00051075See
ECUEcuador Mixed Ancestry0.00041173See
DEUGermany DKMS - Italy minority0.00041159See
DEUGermany DKMS - Spain minority0.00051107See
DEUGermany pop 80.000439689See
ISRIsrael YemenJews0.000415542See
COLColombia Bogotá Cord Blood0.10.00031463See
DEUGermany DKMS - Netherlands minority0.00041374See
USAUSA NMDP North American Amerindian0.000335791See
USAUSA NMDP Filipino0.000250614See
USAUSA NMDP Japanese0.000224582See
USAUSA Hispanic pop 20.00031999See
DEUGermany pop 60.00028862See
CHNChina Jiangsu Han0.00023238See
CZECzech Republic NMDR0.00025099See
HRVCroatia pop 40.00024000See
ISRIsrael USSR Jews0.000245681See
ISRIsrael Kavkazi Jews0.00022840See
USAUSA NMDP Hawaiian or other Pacific Islander0.000211499See
ISRIsrael Iraq Jews0.000213270See
USAUSA NMDP Caribean Black0.000233328See
DEUGermany DKMS - German donors0.00013456066See
ISRIsrael Georgia Jews0.00014471See
USAUSA NMDP European Caucasian0.00011242890See
USAUSA NMDP Chinese0.000199672See
POLPoland DKMS0.000220653See
USAUSA NMDP Vietnamese0.000143540See
HKGHong Kong Chinese BMDR0.00017595See
USAUSA NMDP Mexican or Chicano0.0001261235See
USAUSA NMDP Korean0.000177584See
USAUSA NMDP African American pop 20.0000416581See
USAUSA NMDP African0.000028557See
ISRIsrael Morocco Jews0.000036718See
ITAItaly Bergamo0.00.0000101See
MEXMexico Hidalgo Rural0.000081See
MEXMexico Mexico City Metropolitan Area Rural0.0000150See
MEXMexico Tlaxcala Rural0.0000830See
MEXMexico Puebla Rural0.0000833See
MEXMexico Oaxaca Rural0.0000485See
MEXMexico Morelos Rural0.000030See
MEXMexico Tabasco Rural0.0000142See
MEXMexico Chiapas Rural0.0000121See
MEXMexico Campeche Rural0.000047See
MEXMexico Yucatan Rural0.0000132See
MEXMexico Quintana Roo Rural0.000050See
KORSouth Korea pop 30.0000485See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Mexico City West0.000033See
MEXMexico Yucatan, Merida0.0000192See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Tabasco, Villahermosa0.000082See
MEXMexico Morelos, Cuernavaca0.000082See
MEXMexico Oaxaca, Oaxaca city0.0000151See
MEXMexico Guerrero state0.0000144See
MEXMexico Puebla, Puebla city0.00001994See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Mexico City South0.000052See
MEXMexico Mexico City East0.000079See
MEXMexico Mexico City Center0.0000152See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Veracruz, Xalapa0.0000187See
MEXMexico Veracruz, Veracruz city0.0000171See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Veracruz, Cordoba0.000056See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Aguascalientes state0.000095See
MEXMexico Nuevo Leon, Monterrey city0.0000226See
MEXMexico Colima, Colima city0.000061See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Michoacan, Morelia0.0000150See
MEXMexico Jalisco, Zapopan0.0000168See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Jalisco, Guadalajara city0.00001189See
MEXMexico Nayarit, Tepic0.000097See
MEXMexico Zacatecas, Fresnillo0.0000103See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Coahuila, Torreon0.0000396See
MEXMexico Coahuila, Saltillo0.000072See
MEXMexico Durango, Durango city0.0000153See
MEXMexico Chihuahua, Ciudad Juarez0.0000106See
MEXMexico Chihuahua Chihuahua City0.0000119See
MEXMexico Sinaloa, Culiacán0.0000103See
MEXMexico Sonora, Hermosillo0.000099See
MEXMexico Sonora, Ciudad Obregón0.0000143See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Baja Californa, Mexicali0.0000100See
MARMorocco Nador Metalsa pop 20.000073See
MARMorocco Settat Chaouya0.00.000098See
NLDNetherlands Leiden0.00001305See
PHLPhilippines Ivatan0.00.000050See
HKGHong Kong Chinese0.00.0000569See
MEXMexico Baja California, Tijuana0.000025See
MEXMexico Baja California Rural0.000050See
MEXMexico Sonora Rural0.0000197See
MEXMexico Sinaloa Rural0.0000183See
MEXMexico Chihuahua Rural0.0000236See
MEXMexico Durango Rural0.0000326See
MEXMexico Coahuila Rural0.0000216See
MEXMexico Zacatecas Rural0.0000266See
MEXMexico Nayarit Rural0.000064See
MEXMexico Jalisco Rural0.0000585See
MEXMexico Michoacan Rural0.0000348See
MEXMexico Guanajuato Rural0.0000162See
MEXMexico Colima Rural0.000043See
MEXMexico Nuevo Leon Rural0.0000439See
MEXMexico Queretaro Rural0.000043See
MEXMexico Tamaulipas Rural0.0000125See
MEXMexico San Luis Potosi Rural0.000087See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
ECUEcuador Coast Mixed Ancestry0.0000238See
ECUEcuador Amazonia Mixed Ancestry0.000039See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina Inner Mongolia Region0.0000102See
CHNChina Qinghai Province Hui0.0000110See
BRABrazil Belo Horizonte Caucasian0.00.000095See
BFABurkina Faso Fulani0.000049See
BFABurkina Faso Rimaibe0.000047See
AUSAustralia Yuendumu Aborigine0.0000191See
ARGArgentina Gran Chaco Western Toba Pilaga0.00.000019See
USAUSA European American pop 20.00001245See
USAUSA North American Native0.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Caucasian pop 20.0000265See
USAUSA African American0.0000252See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
CHESwitzerland Basel0.00001888See
SGPSingapore SGVP Malay MAS0.000089See
SGPSingapore Chinese0.00.0000149See
ZAFSouth Africa Natal Zulu0.00.0000100See
USAUSA African American pop 40.00002411See
CHESwitzerland Sion0.0000832See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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