Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 113 time(s) and present in 60 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MEXMexico Tixcacaltuyub Maya0.268767See
MEXMexico Chiapas Lacandon Mayans0.1376218See
MEXMexico Oaxaca Jamiltepec Mixtec0.104096See
MEXMexico Mixtec0.103097See
CMRCameroon Bakola Pygmy12.00.061950See
NICNicaragua Managua11.70.0584339See
MEXMexico Chichen Itza Maya (prehispanic)0.053247See
MEXMexico Mexico City Mestizo population0.0420143See
MEXMexico Mestizo7.30.037041See
MEXMexico Mexico City Mestizo pop 20.0342234See
USAUSA South Texas Hispanic0.0260194See
USAUSA NMDP Mexican or Chicano0.0195261235See
USAUSA NMDP Hispanic South or Central American0.0167146714See
CAFCentral African Republic Mbenzele Pygmy3.00.015136See
CUBCuba Caucasian2.90.014070See
USAUSA Hispanic pop 20.01381999See
MEXMexico Mexico City Tlalpan2.70.0136330See
USAUSA South Dakota Lakota Sioux0.0120302See
ASMAmerican Samoa0.010051See
USAUSA Alaska Yupik0.0100252See
INDIndia West Bhil0.010050See
USAUSA Hispanic0.0090234See
SWESweden Southern Sami0.0080130See
MEXMexico Veracruz Xalapa1.20.006084See
USAUSA NMDP American Indian South or Central America0.00605926See
ESPSpain Andalusia Romani0.006099See
USAUSA San Antonio Caucasian0.0030222See
USAUSA San Diego0.60.0030496See
USAUSA NMDP Caribean Hispanic0.0027115374See
USAUSA NMDP Caribean Indian0.002014339See
USAUSA NMDP Alaska Native or Aleut0.00201376See
USAUSA NMDP North American Amerindian0.001635791See
ISRIsrael Ashkenazi Jews pop 30.00084625See
DEUGermany DKMS - Italy minority0.00081159See
USAUSA NMDP Hawaiian or other Pacific Islander0.000511499See
DEUGermany DKMS - Spain minority0.00051107See
USAUSA NMDP Caribean Black0.000333328See
ISRIsrael YemenJews0.000315542See
ISRIsrael Ethiopia Jews0.00035928See
USAUSA Asian pop 20.00031772See
ISRIsrael Bukhara Jews0.00022317See
USAUSA NMDP Filipino0.000250614See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000270890See
ISRIsrael Poland Jews0.000113871See
USAUSA NMDP African0.000128557See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.00.00014335See
USAUSA NMDP African American pop 20.0001416581See
USAUSA NMDP European Caucasian0.00011242890See
ISRIsrael Morocco Jews0.000136718See
ISRIsrael Iraq Jews0.000113270See
ISRIsrael Georgia Jews0.00004471See
USAUSA NMDP South Asian Indian0.0000185391See
ISRIsrael USSR Jews0.000045681See
USAUSA NMDP Vietnamese0.000043540See
USAUSA NMDP Japanese0.000024582See
ISRIsrael Tunisia Jews0.00009070See
ISRIsrael USA Jews0.00006058See
USAUSA NMDP Korean0.000077584See
DEUGermany DKMS - German donors0.00003456066See
NLDNetherlands Leiden0.00001305See
USAUSA Caucasian pop 40.00001070See
DEUGermany pop 80.000039689See
CHNChina Tibet Region Tibetan0.0000158See
USAUSA African American pop 40.00002411See
USAUSA North American Native0.0000187See
USAUSA Asian0.0000358See
MARMorocco Nador Metalsa pop 20.000073See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
CHNChina North Han0.0000105See
PAKPakistan Karachi Parsi0.000091See
INDIndia Khandesh Region Pawra0.000050See
INDIndia Mumbai Maratha0.000091See
HKGHong Kong Chinese0.00.0000569See
ITAItaly Bergamo0.00.0000101See
SGPSingapore Chinese0.00.0000149See
ZAFSouth Africa Natal Zulu0.00.0000100See
NIRIreland Northern0.00.00001000See
INDIndia West Coast Parsi0.000050See
CZECzech Republic0.0000106See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
MARMorocco Settat Chaouya0.00.000098See
USAUSA Caucasian pop 20.0000265See
USAUSA African American0.0000252See
SCOScotland Orkney0.00.000099See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CUBCuba Mixed Race0.00.000042See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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