Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.

Allele: 
   

DRB1*04:02

 
Allele reported 332 time(s) and present in 275 population(s).

Population Phenotype
Frequency (%)
Allele
Frequency
(in_decimals)
Sample
Size
IMGT/HLA¹
Database
Distribution² Haplotype³
Association
Notesª
TUNTunisia Ghannouch0.165082See
ISRIsrael Ashkenazi Jews0.156080See
ISRIsrael Poland Jews0.133813871See
ISRIsrael USA Jews0.12836058See
ISRIsrael Kavkazi Jews0.12732840See
ISRIsrael Ashkenazi Jews pop 30.11494625See
ISRIsrael Argentina Jews0.10774307See
ISRIsrael Non Ashkenazi Jews0.099080See
ISRIsrael USSR Jews0.091945681See
LBNLebanon Yuhmur0.086082See
IRNIran Azeri0.0850100See
ISRIsrael Ashkenazi Jews pop 20.0830132See
DZAAlgeria Oran0.0810100See
ISRIsrael YemenJews0.080315542See
ISRIsrael Yemenite Jews0.075076See
MARMorocco Settat Chaouya0.071098See
MARMorocco Atlantic Coast Chaouya0.070098See
CHLChile Mapuche0.069266See
MARMorocco Nador Metalsa0.066099See
TUNTunisia Matmata Berber0.062081See
SAUSaudi Arabia11.80.060818See
GRCCretan Islanders0.0565124See
IRNIran Kurd0.0550100See
ISRIsrael Morocco Jews0.052436718See
ISRIsrael Bukhara Jews0.05142317See
ISRIsrael Iranian Jews0.0510101See
GRCGreece Crete0.0510135See
DEUGermany DKMS - Turkey minority0.04924856See
TUNTunisia pop 30.0490104See
MARMorocco0.046096See
ARMArmenia combined Regions0.0450100See
ISRIsrael Iraq Jews0.043613270See
BRABrazil South Caucasian0.041773See
DZAAlgeria pop 28.00.0408106See
ISRIsrael Tunisia Jews0.04089070See
AREUnited Arab Emirates Abu Dhabi0.038552See
ISRIsrael Libya Jews0.03693739See
BGRBulgaria0.036055See
PRTPortugal Azores Terceira Island7.00.0351130See
SAUSaudi Arabia pop 6 (G)0.034828927See
GAZGaza Palestinians0.0330165See
ITAItaly Sardinia pop26.60.03301129See
DEUGermany DKMS - Bosnia and Herzegovina minority0.03111028See
MKDMacedonia pop 20.031080See
ISRIsrael Libyan Jews0.0300119See
DZAAlgeria0.030097See
IRNIran pop 30.0300100See
GEOGeorgia Caucasus Tbilisi0.0294119See
IRNIran pop 20.0292120See
TUNTunisia Gabes Arab0.029096See
TUNTunisia Jerba Berber0.029055See
ISRIsrael Arab0.0280109See
ESPSpain Murcia0.0280173See
PRTAzores Terceira Island0.0270130See
PRTAzores Central Islands0.027059See
MARMorocco Souss Region0.027098See
ISRIsrael Moroccan Jews0.0270113See
GTMGuatemala Kaqchikel NA-DHS_8 (G)5.30.026319See
TUNTunisia Gabes0.026395See
USAUSA Mexican American Mestizo pop 30.0260116See
PRTAzores Oriental Islands0.026043See
TURTurkey pop 10.0260250See
HRVCroatia pop 40.02554000See
DEUGermany DKMS - Greece minority0.02511894See
BRABrazil Terena5.10.025060See
LBNLebanon Niha el Shouff0.025061See
GEOGeorgia Svaneti Region Svan0.025080See
CHLChile Huilliche NA-DHS_14 (G)5.00.025020See
KOSKosovo4.80.0242124See
GRCGreece pop 84.80.024183See
ISRIsrael Arab pop 20.023812301See
GAZGaza4.80.023842See
MEXMexico Veracruz Xalapa4.80.023884See
DEUGermany DKMS - Croatia minority0.02382057See
ESPSpain Las Alpujarras0.023585See
CHNChina Harbin Manchu0.0230172See
BRABrazil North East Mixed0.0230205See
DEUGermany DKMS - Portugal minority0.02301176See
USAUSA NMDP Middle Eastern or North Coast of Africa0.022770890See
SAUSaudi Arabia pop 53.80.0222158See
LBNLebanon Kafar Zubian0.022094See
RUSRussia Tuva Todja0.022022See
DEUGermany DKMS - Romania minority0.02191234See
MEXMexico Mexico City Mestizo pop 20.0214234See
ISRIsrael Iran Jews0.02118153See
IRNIran Fars Parsi0.021073See
RUSRussia Siberia Kushun Buryat0.020025See
PRTPortugal Center0.020050See
PRTPortugal South0.020049See
TUNTunisia4.00.0200100See
ESPSpain Granada0.0200280See
ESPSpain Arratia Valley Basque0.020083See
SAUSaudi Arabia pop 30.020050See
GRCGreece pop 40.020098See
USAUSA Hispanic pop 20.01951999See
SAUSaudi Arabia Guraiat and Hail3.90.0190213See
MKDMacedonia pop 10.0190158See
RUSRussia Siberia Eskimo0.019070See
MEXMexico Highlands Mestizos3.80.0190160See
DEUGermany DKMS - Spain minority0.01901107See
GRCGreece pop33.70.0186246See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,3.60.01824335See
SVNSlovenia pop 23.60.0181140See
CHNChina Urumqi Uyghur3.50.018057See
ESPSpain North Cantabria0.018083See
MKDMacedonia pop 30.0170172See
ITAItaly Central0.0170380See
ESPSpain Barcelona3.40.0170941See
ARGArgentina Buenos Aires3.40.0170466See
DEUGermany DKMS - Italy minority0.01681159See
NICNicaragua Managua3.00.0165339See
USAUSA Italy Ancestry0.0160273See
INDIndia Northeast Shia0.0160190See
INDIndia Northeast Mech0.016063See
PRTMadeira0.0160185See
ESPSpain North Cabuerniga0.016095See
ESPSpain Pas Valley0.016088See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.01601058See
CPVCape Verde Northwestern Islands0.016062See
NLDNetherlands UMCU3.10.015664See
MEXMexico Mexico City Tlalpan3.00.0152330See
FRAFrance West3.00.0151100See
SVNSlovenia3.00.0151100See
RUSRussia Karelia0.01501075See
BRABrazil Southeast Caucasian2.90.0150103See
MEXMexico Guanajuato and Jalisco Mestizo3.00.0150101See
MNGMongolia Khalkha pop 20.0150202See
BRABrazil Mixed0.0150108See
RUSRussia Siberia Khanty Mansi0.015068See
IRNIran Yazd Zoroastrian0.015065See
BOLBolivia Quechua0.014569See
USAUSA NMDP Hispanic South or Central American0.0143146714See
USAUSA San Francisco Caucasian0.0140220See
ITAItaly pop 50.0140975See
FRAFrance South0.0140350See
MEXMexico Mexico City Mestizo population0.0140143See
MEXMexico Mexico City Mestizo pop 30.0140256See
MEXMexico Nahua/Aztec Santo Domingo Ocotitlan0.013773See
USAUSA Caucasian pop 50.0130268See
INDIndia Northeast Mathur0.0130155See
INDIndia Northeast Rastogi0.0130196See
USAUSA Eastern European0.0130558See
CHLChile Santiago0.0127920See
USAUSA NMDP Caribean Hispanic0.0126115374See
BRABrazil Paraná Caucasian2.50.0125641See
USAUSA NMDP Mexican or Chicano0.0123261235See
BRABrazil Southeast Mixed Race2.40.012042See
USAUSA Caucasian Pittsburgh2.40.0120177See
GRCGreece pop22.40.0120120See
ISRIsrael Druze0.01145914See
MEXMexico Chihuahua Chihuahua City Pop 22.30.011488See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.01103830See
CHNChina Xinjiang Province Uyghur0.011092See
USAUSA Mexican American Mestizo0.0110553See
USAUSA NMDP European Caucasian0.01061242890See
DEUGermany pop 80.010639689See
COLColombia Bogotá Cord Blood2.10.01061463See
CZECzech Republic NMDR0.01035099See
USAUSA NMDP Caribean Indian0.010014339See
FRAFrance Rennes pop 30.0100200See
MTQMartinique0.0100100See
DEUGermany DKMS - France minority0.01001406See
CHLChile Santiago Mixed2.00.010070See
ESPSpain Northwest Lugo2.00.0100145See
FRAFrance Rennes0.0100200See
RUSRussia Siberia North East Kamchatka Koryak0.010092See
SDNSudan Mixed2.00.0100200See
CZECzech Republic0.0100106See
USAUSA South Texas Hispanic0.0100194See
ITAItaly North pop 32.10.010097See
PERPeru Titikaka Lake Uros0.0100105See
USAUSA Caucasian1.90.009561655See
POLPoland DKMS0.009320653See
PERPeru Titikaka Lake Uro0.0090105See
PRTMadeira pop 20.0090173See
HRVCroatia Krk Island0.0090212See
CHNChina Beijing and Xian0.0090171See
DNKDenmark0.009055See
COLColombia Guajira Peninsula Wayuu0.009088See
USAUSA Minnesota Olmsted0.0090339See
PANPanama0.0088462See
GRCGreece pop 60.0083242See
ENGEngland North West1.70.0080298See
INDIndia Northeast Vaish0.0080198See
ENGEngland pop 61.70.0080177See
FRAFrance Southeast1.50.0080130See
INDIndia Lucknow1.70.0080123See
DEUGermany pop 60.00768862See
MEXMexico Tixcacaltuyub Maya0.007567See
ISRIsrael Georgia Jews0.00714471See
FINFinland pop20.0070150See
IDNIndonesia Java Western1.30.0070236See
IDNIndonesia Sundanese and Javanese0.0070201See
CUBCuba Mixed0.007078See
USAUSA Philadelphia Caucasian1.40.0070141See
USAUSA Southern California Mestizo1.40.007073See
BRABrazil Puyanawa1.30.0070150See
USAUSA San Diego1.40.0070496See
FRAFrance French Bone Marrow Donor Registry0.006842623See
ECUEcuadorean Amerindians0.006775See
DEUGermany DKMS - German donors0.00673456066See
NLDNetherlands1.30.0065447See
USAUSA NMDP South Asian Indian0.0064185391See
USAUSA Caucasian Houston1.20.0060194See
COKCook Islands Rarotonga0.006078See
BRABrazil Guarani Nandeva0.006086See
USAUSA NMDP Southeast Asian0.005927978See
DEUGermany DKMS - Austria minority0.00531698See
CZECzech Republic pop 21.00.005099See
INDIndia Uttar Pradesh0.0050202See
COLColombia Antioquia Paisa0.0050100See
POLPoland0.0050200See
ESPSpain Andalusia0.005099See
CHNChina Inner Mongolia Region Ewenki0.005094See
INDIndia Northeast Rajbanshi0.005098See
USAUSA NMDP American Indian South or Central America0.00505926See
USAUSA NMDP Alaska Native or Aleut0.00501376See
BRABrazil Mato Grosso do Sul0.0050203See
CHNChina pop11.00.0050103See
MEXMexico Mixtec0.005097See
ITAItaly Rome1.00.0050100See
ITAItaly Bergamo1.00.0050101See
RUSRussia Northwest Slavic0.0050200See
BELBelgium1.00.005099See
POLPoland Wielkopolska Region0.005099See
MEXMexico Oaxaca Jamiltepec Mixtec0.005096See
RUSRussia Bering Island Aleuts0.0048104See
DEUGermany pop 30.90.0045111See
DEUGermany DKMS - United Kingdom minority0.00431043See
DEUGermany DKMS - Netherlands minority0.00441374See
NLDNetherlands Leiden0.00401305See
USAUSA Spain Ancestry0.0040279See
ENGEngland Bedfordshire0.80.0040354See
USAUSA Colorado Univ Cord Blood Bank African American0.0040261See
GTMGuatemala Mayan0.0040132See
USAUSA Caucasian pop 40.00391070See
USAUSA NMDP North American Amerindian0.003835791See
USAUSA Asian pop 20.00371772See
INDIndia UCBB_Central Indian HLA0.60.00314204See
RUSRussia Transbaikal Territory Buryats1.00.0030150See
INDIndia Northeast Sunni0.0030188See
USAUSA African American pop 70.0030193See
USAUSA Caucasian Bethesda0.60.0030307See
NIRIreland Northern0.60.00301000See
USAUSA San Antonio Caucasian0.0023222See
USAUSA NMDP Hawaiian or other Pacific Islander0.002311499See
CHNChina Jiangsu Han0.00203238See
AUTAustria0.50.0020200See
CHNChina Canton Han0.0020264See
IRLIreland South0.40.0020250See
CHNChina Beijing Shijiazhuang Tianjian Han0.0020618See
RWARwanda Kigali Hutu and Tutsi0.0020281See
DEUGermany DKMS - China minority0.00201282See
INDIndia Tamil Nadu0.00182492See
MYSMalaysia Peninsular Malay0.30.0016951See
USAUSA NMDP Caribean Black0.001533328See
USAUSA NMDP Filipino0.001250614See
CHNChina Hubei Han0.20.00123732See
USAUSA NMDP African0.001228557See
TWNTaiwan Han Chinese0.0010504See
USAUSA African American pop 30.0010564See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
USAUSA NMDP African American pop 20.0008416581See
CHNChina Zhejiang Han pop 20.0006833See
USAUSA NMDP Chinese0.000599672See
USAUSA NMDP Japanese0.000524582See
KORSouth Korea pop 100.00044128See
USAUSA African American pop 40.00042411See
HKGHong Kong Chinese BMDR0.00027595See
JPNJapan pop 160.000118604See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000146682See
USAUSA NMDP Korean0.000177584See
ISRIsrael Ethiopia Jews0.00015928See
USAUSA NMDP Vietnamese0.000043540See
ZAFSouth Africa Caucasians0.0000102See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
KORSouth Korea pop 40.00.0000211See
INDIndia Northeast Kayastha0.0000190See
INDIndia Northeast Lachung0.000058See
INDIndia North0.00.000085See
IDNIndonesia Java pop 20.000036See
CZECzech Republic Romani0.00.000034See
NORNorway0.0000181See
ARGArgentina Rio Negro Mapuche0.000034See
ARGArgentina Chubut Tehuelche0.000023See
ARGArgentina Salta Wichi0.000024See
PRYParaguay Lengua0.000017See
ISRIsrael Ethiopian Jews0.0000122See
CHNChina Harbin Korean0.0000201See
CPVCape Verde Southeastern Islands0.000062See
GNBGuinea Bissau0.000065See
BRABrazil Central Plateau Xavante0.000074See
ARGArgentina Gran Chaco Eastern Toba0.0000135See
ARGArgentina Gran Chaco Mataco Wichi0.000049See
ARGArgentina Gran Chaco Western Toba Pilaga0.000019See
RUSRussia Siberia Gvaysugi Udege0.000025See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.000032See
RUSRussia Siberia Chukotka Peninsula Chukchi0.000059See
RUSRussia Siberia Chukotka Peninsula Eskimo0.000080See
RUSRussia Siberia Chukchi0.000071See
RUSRussia Siberia Sulamai Ket0.000022See
RUSRussia Siberia Polygus Evenk0.000035See
RUSRussia Tuva pop30.000044See
KORSouth Korea pop 30.0000485See
RUSRussia Siberia Ulchi0.000073See
RUSRussia Siberia Negidal0.000035See
RUSRussia Siberia Khabarovsk Evenki0.000025See
CHNChina Urumqi Han0.000059See
CHNChina Urumqi Kazak0.000042See
JPNJapan Hyogo Osaka and Nagano0.0000195See
MNGMongolia Hoton0.000085See
RUSRussia Siberia Irkutsk Tofalar0.000043See
KORSouth Korea pop 20.00.0000207See
USAUSA Alaska Yupik0.0000252See
USAUSA Colorado Univ Cord Blood Bank Asian0.0000100See
BRABrazil Kaingang0.0000235See
JAMJamaica0.0000132See
CANCanada British Columbia Athabaskan0.000062See
CANCanada British Columbia Penutian0.000026See
PRTPortugal North0.000046See
USAUSA African American Bethesda0.00.0000187See
COLColombia Bogota and Medellin Mestizo0.000065See
NIUNiue0.000070See
WSMWestern Samoa and Tokelau0.000051See
NRUNauru0.000067See
KIRKiribati0.000062See
IDNIndonesia Java Yogyakarta Region0.000062See
CHNChina Hong Kong and Singapore0.0000135See
BRABrazil Guarani M bya0.000093See
CAFCentral African Republic Aka Pygmy0.00.000093See
CODCongo Kinshasa Bantu0.00.000090See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See

Frequency data at lower resolution for this allele can be found in links below


Allele  Number of Populations 

Notes:

* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


   

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

support@allelefrequencies.net


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