Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 154 time(s) and present in 112 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
NZLNew Zealand Maori with Full Ancestry63.00.359046See
NZLNew Zealand Maori with Admixed History47.60.2570105See
TWNTaiwan Taroko25.50.145055See
TWNTaiwan Bunun22.80.1340101See
NZLNew Zealand Polynesians with Admixed History25.90.130027See
ASMAmerican Samoa0.120051See
TWNTaiwan Tsou21.60.118051See
TWNTaiwan Atayal23.60.1180106See
CHNChina Guizhou Province Miao pop 20.108085See
TWNTaiwan Thao20.00.100030See
NZLNew Zealand Polynesians with Full Ancestry19.00.095021See
CHNChina Guizhou Province Bouyei0.0880109See
CHNChina Guizhou Province Shui0.0830153See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0644233See
CHNChina Yunnan Province Jinuo0.0640109See
CHNChina Guangxi Region Maonan0.0600108See
TWNTaiwan Rukai10.00.060050See
TWNTaiwan Paiwan11.80.059051See
CHNChina Southwest Dai0.0520124See
USAUSA NMDP Hawaiian or other Pacific Islander0.050211499See
JPNJapan Hokkaido Ainu0.050050See
CHNChina Tibet Region Tibetan0.0470158See
MYSMalaysia Peninsular Chinese9.30.0464194See
TWNTaiwan Puyuma8.00.040050See
TWNTaiwan Pazeh7.30.036055See
TWNTaiwan Hakka5.50.036055See
TWNTaiwan Han Chinese0.0350504See
CHNChina Marrow Donor Registry0.0350600See
HKGHong Kong Chinese cord blood registry0.03283892See
CHNChina Hubei Han6.40.03223732See
SGPSingapore Chinese6.00.0300149See
TWNTaiwan Tzu Chi Morrow Donor Registry0.029746682See
HKGHong Kong Chinese BMDR0.02947595See
CHNChina Beijing Shijiazhuang Tianjian Han0.0290618See
CHNChina North Han0.0290105See
TWNTaiwan Minnan pop 15.90.0290102See
TWNTaiwan Siraya5.90.029051See
TWNTaiwan pop 30.0290212See
USAUSA NMDP Chinese0.027699672See
USAUSA NMDP Japanese0.027224582See
TWNTaiwan Tzu Chi Cord Blood Bank0.0270710See
SGPSingapore SGVP Chinese CHS0.027096See
KORSouth Korea pop 30.0270485See
JPNJapan pop 160.026518604See
VNMVietnam Hanoi Kinh pop 20.0260170See
USAUSA Asian0.0250358See
CHNChina Jiangsu Province Han0.0234334See
CHNChina Shanxi HIV negative0.023022See
DEUGermany DKMS - China minority0.02301282See
JPNJapan pop 50.0220117See
CHNChina Jiangsu Han0.02203238See
HKGHong Kong Chinese4.40.0220569See
CHNChina Yunnan Province Han0.0200101See
THAThailand pop 30.020049See
TWNTaiwan Saisiat3.90.020051See
TWNTaiwan Ami4.10.020098See
USAUSA Hawaii Okinawa0.0190106See
JPNJapan Central0.0190371See
JPNJapan pop 30.01901018See
USAUSA NMDP Vietnamese0.019043540See
CHNChina Qinghai Province Hui0.0180110See
CHNChina South Han0.0180284See
KORSouth Korea pop 100.01744128See
USAUSA NMDP Korean0.016477584See
TWNTaiwan pop 20.0160364See
USAUSA Asian pop 20.01591772See
CHNChina Guangzhou0.0150102See
CHNChina Sichuan HIV negative0.015034See
NCLNew Caledonia0.010065See
PHLPhilippines Ivatan2.00.010050See
USAUSA NMDP Filipino0.009050614See
USAUSA Caucasian pop 20.0090265See
PNGPapua New Guinea Madang0.009065See
PNGPapua New Guinea Wanigela Keapara0.008066See
CHNChina Yunnan Province Wa0.0080119See
USAUSA NMDP Southeast Asian0.007627978See
CHNChina Yunnan Hani0.0070150See
CHNChina Yunnan Province Nu0.0060107See
SGPSingapore SGVP Malay MAS0.006089See
MEXMexico Chihuahua Chihuahua City Pop 21.10.005788See
MYSMalaysia Peninsular Malay1.10.0053951See
CHNChina Guangdong Province Meizhou Han0.0050100See
CHNChina Inner Mongolia Region0.0050102See
INDIndia Northeast UCBB0.70.0034296See
USAUSA African American0.0020252See
ISRIsrael Bukhara Jews0.00062317See
USAUSA NMDP South Asian Indian0.0005185391See
INDIndia Tamil Nadu0.00042492See
DEUGermany DKMS - Turkey minority0.00044856See
CHESwitzerland Bern0.00043545See
ISRIsrael Arab pop 20.000312301See
INDIndia East UCBB0.00.00022403See
INDIndia West UCBB0.00.00025829See
INDIndia North UCBB0.00.00025849See
INDIndia South UCBB0.00.000111446See
INDIndia Central UCBB0.00.00014204See
DEUGermany pop 80.000139689See
POLPoland DKMS0.000220653See
USAUSA NMDP Mexican or Chicano0.0001261235See
USAUSA NMDP Caribean Black0.000133328See
USAUSA NMDP Hispanic South or Central American0.0001146714See
USAUSA NMDP African0.000128557See
USAUSA NMDP African American pop 20.0001416581See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000070890See
USAUSA NMDP Caribean Hispanic0.0000115374See
USAUSA NMDP North American Amerindian0.000035791See
DEUGermany DKMS - German donors0.00003456066See
USAUSA NMDP European Caucasian0.00001242890See
ISRIsrael Morocco Jews0.000036718See
ISRIsrael USSR Jews0.000045681See
ITAItaly pop 50.0000975See
NIRIreland Northern0.00.00001000See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
MEXMexico Mestizo0.00.000041See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
NLDNetherlands Leiden0.00001305See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CHNChina Beijing0.000067See
USAUSA Hispanic0.0000234See
USAUSA North American Native0.0000187See
USAUSA Hispanic pop 20.00001999See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA African American pop 40.00002411See
USAUSA European American pop 20.00001245See
USAUSA African American pop 80.0000605See
TWNTaiwan Tao0.00.000050See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
ZAFSouth Africa Natal Zulu0.00.0000100See
CHESwitzerland Aargau-Solothurn0.00001838See
SGPSingapore SGVP. Indian INS0.000086See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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