Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 133 time(s) and present in 104 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
COLColombia Embera NA-DHS_19 (G)64.30.428614See
VENVenezuela Sierra de Perija Yucpa0.361073See
MEXMexico Mixtec0.222097See
MEXMexico Oaxaca Jamiltepec Mixtec0.219096See
MEXMexico Tixcacaltuyub Maya0.201567See
MEXMexico Mixtec NA-DHS_5 (G)35.00.175020See
MEXMexico Chiapas Lacandon Mayans0.1651218See
COLColombia Waunana NA-DHS_20 (G)30.00.150020See
MEXMexico Oaxaca Zapotec0.127090See
MEXMexico Zapotec NA-DHS_7 (G)23.50.117620See
MEXMexico Oaxaca Mixtec0.0980103See
MEXMexico Mexico City Mestizo population0.0839143See
MEXMexico Mexico City Mestizo pop 20.0791234See
GTMGuatemala Kaqchikel NA-DHS_8 (G)15.80.078919See
COLColombia/Brazil Ticuna Arara NA-DHS_21 (G)7.10.071417See
MEXMexico Chichen Itza Maya (prehispanic)0.053247See
COLColombia/Brazil Ticuna Tarapaca NA-DHS_22 (G)10.50.052619See
BRABrazil Puyanawa10.00.0500150See
PRYParaguay/Argentina Guarani NA-DHS_23 (G)10.00.050010See
MEXMexico Mestizo9.80.049041See
PRYParaguay/Argentina Ache NA-DHS_24 (G)9.10.045513See
USAUSA Arizona Pima0.0450100See
USAUSA South Texas Hispanic0.0390194See
USAUSA Mexican American Mestizo0.0370553See
COLColombia Inga NA-DHS_11 (G)7.10.035716See
COLColombia Wayuu NA-DHS_15 (G)6.70.033315See
USAUSA NMDP Mexican or Chicano0.0322261235See
COLColombia Zenu NA-DHS_18 (G)6.30.031316See
COLColombia Bogotá Cord Blood5.70.02871463See
NICNicaragua Managua5.70.0286339See
MEXMexico Mixe NA-DHS_6 (G)5.00.025020See
MEXMexico Guadalajara Mestizo pop 20.0240103See
BOLBolivia/Peru Quechua NA-DHS_12 (G)4.80.023821See
USAUSA NMDP Hispanic South or Central American0.0233146714See
USAUSA Hispanic pop 20.02301999See
ARGArgentina Rosario Toba4.70.023086See
COLColombia North Chimila Amerindians0.021247See
USAUSA Hispanic0.0210234See
MEXMexico Oaxaca Mixe0.019055See
USAUSA Spain Ancestry0.0180279See
ARGArgentina Gran Chaco Eastern Toba3.50.0170135See
CUBCuba Caucasian2.90.014070See
MEXMexico Chihuahua Tarahumara0.011044See
USAUSA NMDP Caribean Hispanic0.0109115374See
NZLNew Zealand Maori with Admixed History1.90.0100105See
USAUSA NMDP Hawaiian or other Pacific Islander0.007011499See
USAUSA NMDP Caribean Indian0.007014339See
MARMorocco Atlantic Coast Chaouya0.007098See
MARMorocco Settat Chaouya1.40.007098See
USAUSA San Antonio Caucasian0.0060222See
USAUSA San Diego1.00.0050496See
PERPeru Titikaka Lake Uro0.0050105See
PERPeru Titikaka Lake Uros0.0050105See
USAUSA NMDP American Indian South or Central America0.00505926See
USAUSA North American Native0.0050187See
DEUGermany DKMS - China minority0.00471282See
CHNChina Hubei Han0.90.00443732See
USAUSA NMDP Vietnamese0.003843540See
SGPSingapore Chinese0.70.0030149See
VNMVietnam Hanoi Kinh pop 20.0030170See
HKGHong Kong Chinese0.50.0030569See
MYSMalaysia Peninsular Chinese0.50.0026194See
GRCGreece pop 60.0024242See
CHNChina Jiangsu Province Han0.0023334See
CHNChina Jiangsu Han0.00203238See
CHNChina Marrow Donor Registry0.0020600See
CHNChina Beijing Shijiazhuang Tianjian Han0.0020618See
USAUSA Arizona Gila River Amerindian0.0020492See
USAUSA NMDP Chinese0.002099672See
USAUSA Asian pop 20.00111772See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
TWNTaiwan pop 20.0010364See
TWNTaiwan Tzu Chi Morrow Donor Registry0.001046682See
HKGHong Kong Chinese BMDR0.00107595See
USAUSA NMDP North American Amerindian0.000935791See
HKGHong Kong Chinese cord blood registry0.00083892See
USAUSA NMDP Caribean Black0.000633328See
MYSMalaysia Peninsular Malay0.10.0005951See
DEUGermany DKMS - Turkey minority0.00044856See
DEUGermany DKMS - Spain minority0.00051107See
DEUGermany DKMS - France minority0.00041406See
USAUSA NMDP Southeast Asian0.000327978See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000370890See
USAUSA NMDP Filipino0.000350614See
DEUGermany DKMS - Greece minority0.00031894See
USAUSA NMDP African American pop 20.0002416581See
USAUSA NMDP European Caucasian0.00011242890See
USAUSA NMDP Korean0.000177584See
ISRIsrael Argentina Jews0.00014307See
ISRIsrael Ashkenazi Jews pop 30.00014625See
KORSouth Korea pop 100.00014128See
JPNJapan pop 160.000118604See
DEUGermany pop 80.000139689See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.00.00014335See
POLPoland DKMS0.000220653See
USAUSA NMDP Japanese0.000124582See
ISRIsrael USSR Jews0.000145681See
DEUGermany DKMS - German donors0.00013456066See
USAUSA NMDP African0.000028557See
ISRIsrael Poland Jews0.000013871See
USAUSA NMDP South Asian Indian0.0000185391See
SAUSaudi Arabia pop 6 (G)0.000028927See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian pop 20.0000265See
USAUSA African American0.0000252See
USAUSA European American pop 20.00001245See
USAUSA African American pop 80.0000605See
USAUSA African American pop 40.00002411See
ZAFSouth Africa Natal Zulu0.00.0000100See
USAUSA Asian0.0000358See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
KORSouth Korea pop 30.0000485See
MARMorocco Nador Metalsa pop 20.000073See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
CZECzech Republic0.0000106See
CUBCuba Mixed Race0.00.000042See
CHNChina Tibet Region Tibetan0.0000158See
ARGArgentina Gran Chaco Mataco Wichi0.00.000049See
ARGArgentina Gran Chaco Western Toba Pilaga0.00.000019See
AUSAustralia Yuendumu Aborigine0.0000191See
AUSAustralia New South Wales Caucasian0.0000134See
BRABrazil Belo Horizonte Caucasian0.00.000095See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CHNChina North Han0.0000105See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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