Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 181 time(s) and present in 127 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
PERPeru Titikaka Lake Uro0.5150105See
PERPeru Titikaka Lake Uros0.5140105See
BOLBolivia/Chile Aymara NA-DHS_13 (G)65.00.375020See
MYSMalaysia Pahang Semai29.00.145038See
BOLBolivia/Peru Quechua NA-DHS_12 (G)23.80.142921See
MYSMalaysia Perak Grik Jehai0.140025See
CHNChina Yunnan Bulang0.1250116See
MYSMalaysia Sarawak Bau Bidayuh0.120025See
IDNIndonesia Sundanese and Javanese0.0900201See
IDNIndonesia Java Western16.50.0860236See
USAUSA NMDP Filipino0.081650614See
ARGArgentina Gran Chaco Western Toba Pilaga14.30.071019See
SGPSingapore Riau Malay0.0690132See
MYSMalaysia Jelebu Temuan0.063025See
MYSMalaysia Patani12.00.060025See
PHLPhilippines Ivatan12.00.060050See
USAUSA NMDP Hawaiian or other Pacific Islander0.056311499See
USAUSA Spain Ancestry0.0560279See
MYSMalaysia Mandailing11.10.056027See
IDNIndonesia Java pop 20.056036See
MYSMalaysia Peninsular Malay10.10.0515951See
SGPSingapore Javaneses0.051051See
CHNChina Yunnan Province Jinuo0.0500109See
SGPSingapore SGVP Malay MAS0.048089See
MYSMalaysia Kedah Kensiu9.50.048021See
ARGArgentina Gran Chaco Eastern Toba9.50.0470135See
VNMVietnam Hanoi Kinh pop 20.0410170See
MYSMalaysia Kelantan7.10.036028See
ARGArgentina Rosario Toba5.80.035086See
BRABrazil Terena6.90.035060See
COLColombia Wayuu NA-DHS_15 (G)6.70.033315See
USAUSA NMDP Vietnamese0.025143540See
COLColombia Waunana NA-DHS_20 (G)5.00.025020See
CHNChina Yunnan Province Wa0.0250119See
PNGPapua New Guinea Wanigela Keapara0.023066See
BRABrazil Mixed0.0220108See
TUNTunisia Gabes0.021095See
CHNChina Southwest Dai0.0200124See
COLColombia North Wiwa El Encanto0.019252See
CHNChina Yunnan Hani0.0170150See
MYSMalaysia Peninsular Chinese2.10.0103194See
SGPSingapore Thai0.0100100See
THAThailand pop 30.010049See
CHNChina Guizhou Province Bouyei0.0100109See
HKGHong Kong Chinese1.90.0100569See
USAUSA Asian pop 20.00991772See
ZAFSouth Africa Worcester2.00.0090159See
TWNTaiwan Pazeh1.80.009055See
USAUSA Hispanic0.0090234See
TWNTaiwan pop 20.0080364See
CHNChina Canton Han0.0080264See
CHNChina South Han0.0070284See
CUBCuba Caucasian1.40.007070See
SGPSingapore Chinese1.30.0070149See
USAUSA NMDP Southeast Asian0.006827978See
HKGHong Kong Chinese BMDR0.00627595See
HKGHong Kong Chinese cord blood registry0.00603892See
LKASri Lanka Colombo1.30.0060714See
CHNChina Marrow Donor Registry0.0060600See
SGPSingapore Chinese Han0.006094See
SGPSingapore SGVP. Indian INS0.006086See
USAUSA NMDP Hispanic South or Central American0.0056146714See
COLColombia Bogotá Cord Blood1.10.00551463See
USAUSA NMDP Chinese0.005499672See
CHNChina Jiangsu Province Han0.0053334See
IRNIran Tabriz Azeris0.005297See
INDIndia Delhi pop 21.10.005090See
CHNChina Guangzhou0.0050102See
TWNTaiwan Minnan pop 11.00.0050102See
ZAFSouth Africa Caucasians0.0050102See
USAUSA Caucasian pop 20.0040265See
TWNTaiwan Tzu Chi Cord Blood Bank0.0040710See
MEXMexico Mexico City Mestizo population0.0035143See
INDIndia Northeast UCBB0.70.0034296See
JORJordan Amman0.0030146See
CHNChina Jiangsu Han0.00303238See
USAUSA San Diego0.60.0030496See
TWNTaiwan Tzu Chi Morrow Donor Registry0.003046682See
CHNChina Hubei Han0.60.00283732See
INDIndia East UCBB0.50.00272403See
DEUGermany DKMS - China minority0.00231282See
TWNTaiwan Han Chinese0.0020504See
TWNTaiwan pop 30.0020212See
USAUSA African American pop 30.0020564See
USAUSA NMDP Caribean Indian0.002014339See
MYSMalaysia Peninsular Indian0.40.0018271See
USAUSA NMDP Caribean Hispanic0.0018115374See
USAUSA NMDP Mexican or Chicano0.0015261235See
NICNicaragua Managua0.30.0015339See
MEXMexico Mexico City Tlalpan0.30.0015330See
USAUSA Hispanic pop 20.00131999See
USAUSA African American pop 40.00102411See
USAUSA Asian0.0010358See
USAUSA African American pop 80.0010605See
USAUSA NMDP American Indian South or Central America0.00105926See
NLDNetherlands Leiden0.00101305See
CHNChina Beijing Shijiazhuang Tianjian Han0.0010618See
AREUnited Arab Emirates Pop 10.0010570See
SAUSaudi Arabia pop 6 (G)0.000928927See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.10.00064335See
USAUSA NMDP South Asian Indian0.0006185391See
INDIndia South UCBB0.10.000511446See
USAUSA NMDP Japanese0.000524582See
USAUSA NMDP Caribean Black0.000433328See
INDIndia Tamil Nadu0.00042492See
DEUGermany DKMS - Italy minority0.00041159See
USAUSA NMDP African American pop 20.0004416581See
DEUGermany DKMS - Netherlands minority0.00041374See
JPNJapan pop 160.000218604See
USAUSA NMDP African0.000228557See
INDIndia West UCBB0.00.00025829See
USAUSA NMDP North American Amerindian0.000135791See
INDIndia Central UCBB0.00.00014204See
ISRIsrael Argentina Jews0.00014307See
DEUGermany DKMS - Turkey minority0.00014856See
DEUGermany pop 80.000139689See
CZECzech Republic NMDR0.00015099See
DEUGermany pop 60.00018862See
KORSouth Korea pop 100.00014128See
INDIndia North UCBB0.00.00015849See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000170890See
USAUSA NMDP Korean0.000177584See
DEUGermany DKMS - German donors0.00013456066See
USAUSA NMDP European Caucasian0.00001242890See
ZAFSouth Africa Natal Zulu0.00.0000100See
USAUSA North American Native0.0000187See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA European American pop 20.00001245See
CZECzech Republic0.0000106See
CUBCuba Mixed Race0.00.000042See
ITAItaly North pop 30.00.000097See
ITAItaly pop 50.0000975See
KORSouth Korea pop 30.0000485See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
ARGArgentina Gran Chaco Mataco Wichi0.00.000049See
AUSAustralia Yuendumu Aborigine0.0000191See
AUSAustralia New South Wales Caucasian0.0000134See
BRABrazil Belo Horizonte Caucasian0.00.000095See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CHNChina Beijing0.000067See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina Guizhou Province Miao pop 20.000085See
CHNChina Guizhou Province Shui0.0000153See
CHNChina North Han0.0000105See
USAUSA African American0.0000252See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
SGPSingapore SGVP Chinese CHS0.000096See
NIRIreland Northern0.00.00001000See
NCLNew Caledonia0.000065See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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