Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 381 time(s) and present in 343 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
VENVenezuela Zulia San Jose de Heras Mixed0.275020See
CMRCameroon Ewondo0.263038See
NORNorway Sami0.1800200See
BFABurkina Faso Rimaibe0.170047See
CMRCameroon Uldeme0.143035See
CMRCameroon Podokwo0.140043See
BFABurkina Faso Fulani0.133049See
CMRCameroon Bamileke 20.129035See
TUNTunisia Ghannouch0.122082See
USAUSA OPTN African American0.10701510See
GHAGhana Accre Asutuare Akan0.1040429See
NORNorway pop 20.1030576See
ZAFSouth Africa Natal Zulu20.00.1000100See
MEXMexico Tapachula, Chiapas Mestizo Population19.40.097272See
CUBCuba Mixed0.096078See
CUBCuba Mixed Race16.70.095042See
BFABurkina Faso Mossi0.094053See
BRABrazil Parana Afro Brazilian18.20.091077See
ZAFSouth Africa Tswana14.60.085041See
GRCGreece Crete0.0800135See
BRABrazil Rio Grande do Sul Black0.0800248See
CUBCuba Mixed pop 20.0760189See
GAZGaza Palestinians0.0750165See
BRABrazil REDOME Bahia0.072447399See
PRTPortugal Bragança0.0710301See
TTOTrinidad African0.070067See
RUSRussia Transbaikal Territory Buryats13.00.0700150See
MEXMexico San Luis Potosi Rural0.069087See
MARMorocco pop 20.0680110See
BRABrazil Sao Paulo Mixed13.00.0670239See
MEXMexico Morelos Rural0.066730See
INDIndia Jalpaiguri Toto12.50.064540See
BRABrazil REDOME Pernambuco0.064392332See
BRABrazil Piaui Mixed0.064021943See
BRABrazil REDOME Piaui0.063946140See
BRABrazil REDOME Sergipe0.06367321See
BRABrazil REDOME Rio de Janeiro0.0629139322See
BRABrazil REDOME Minas Gerais0.0612211275See
COLColombia Barranquilla0.0610188See
BRABrazil REDOME Maranhao0.060010180See
MEXMexico Quintana Roo Rural0.060050See
BRABrazil Para State11.20.06005000See
BRABrazil Minas Gerais State Mixed11.30.05901000See
BRABrazil REDOME Rio Grande do Norte0.058546603See
BRABrazil Rio Grande do Norte Mestizo0.058012973See
PRTPortugal Guarda0.0580797See
BRABrazil REDOME Ceara0.0578101217See
BRABrazil REDOME Paraiba0.056543868See
BRABrazil South East Cord Blood0.056311409See
BRABrazil REDOME Tocantins0.056120692See
MARMorocco Casablanca0.0560100See
BRABrazil REDOME Goias0.055988574See
PRTPortugal Viana do Castelo0.0550706See
TUNTunisia pop 30.0550104See
PRTMadeira pop 20.0550173See
BRABrazil REDOME Espirito Santo0.054688485See
BRABrazil REDOME Federal District0.054329549See
BRABrazil REDOME Alagoas0.054325349See
CZECzech Republic Kurd9.50.054174See
PRTMadeira pop 30.0540538See
SAUSaudi Arabia pop 20.0540383See
PRTPortugal Beja0.0540699See
TURTurkey pop 20.0530228See
ARMArmenia living in Iran0.053085See
BRABrazil REDOME Rondonia0.052454396See
GEOGeorgia Kurds0.052030See
ITAItaly South Campania Region10.10.05181089See
BRABrazil REDOME Mato Grosso0.051634649See
BRABrazil REDOME Roraima0.05114140See
ARMArmenia Syunik0.0510117See
ITAItaly East Sicily10.00.050050See
ARMArmenia Yerevan0.0500445See
BRABrazil Parana Cafuzo10.00.0500319See
PRTPortugal North pop 20.04941801See
BRABrazil REDOME Para0.049172637See
ARMArmenia Lori0.0490102See
ARMArmenia living in USA0.0490233See
PRTPortugal Braga0.04901971See
PRTPortugal Leiria0.04901847See
PRTPortugal Castelo Branco0.0490327See
BRABrazil REDOME Acre0.0489859See
MEXMexico Hidalgo, Pachuca0.048841See
BRABrazil REDOME Mato Grosso do Sul0.048695667See
BRABrazil REDOME Sao Paulo0.0476800809See
BRABrazil REDOME Amapa0.047017864See
MEXMexico Puebla Mestizo0.046099See
BRABrazil Rio Grande do Sul Mixed0.0460324See
BRABrazil Parana Mixed race9.10.0460186See
ESPSpain Ibiza0.046088See
BRABrazil REDOME Amazonas0.045824129See
BRABrazil Curitiba-Parana Mixed0.0451264See
BRABrazil Sao Paulo Bauru Mixed0.04503542See
ARMArmenia living in Karabakh0.0450445See
PRTPortugal Vila Real0.04501167See
PRTPortugal Porto0.04507937See
ARGArgentina La Plata9.00.0450100See
PRTPortugal Aveiro0.04505933See
PRTPortugal Lisbon0.044017420See
HRVCroatia pop 20.0440100See
ESPSpain Murcia0.0440173See
PRTPortugal South pop 20.04401021See
BRABrazil Para Cord Blood Unit8.70.0440841See
MEXMexico Tabasco, Villahermosa0.042782See
PRTPortugal Coimbra0.04205057See
ALBAlbanian Kosovo0.0417120See
ESPSpain Sevilla8.30.0414278See
PRTPortugal Setubal0.04105268See
BRABrazil South Ribeirao Preto0.0410184See
BRABrazil REDOME Parana0.0405341639See
FRAFrance Grenoble8.10.04041000See
ESPSpain Majorca0.0400407See
ESPSpain Andalusia0.040099See
MEXMexico Baja California, Tijuana0.040025See
ITAItaly North Pavia pop 30.0398685See
MEXMexico Tamaulipas Rural0.0397125See
SAUSaudi Arabia pop 47.00.0391499See
PRTPortugal Faro0.03901242See
PRTPortugal Santarem0.03903865See
PRTPortugal Viseu0.03902915See
IRNIran pop 10.039064See
PRTPortugal Portalegre0.03901254See
MNGMongolia Oold0.0390104See
BRABrazil REDOME Rio Grande do Sul0.0382241329See
ARMArmenia living in Lebanon0.0380368See
RUSRussia Tatars0.0380355See
MEXMexico Veracruz, Veracruz city0.0378171See
SDNSudan East Rashaida7.40.037727See
BRABrazil REDOME Santa Catarina0.0375106673See
BIHBosnia and Herzegovina pop 27.50.0375120See
BRABrazil Paraná Caucasian7.50.0374641See
BRABrazil Rio Grande do Sul Caucasoid0.03704428See
PRTPortugal Evora0.0370737See
MEXMexico Mestizo7.30.037041See
RUSRussia Chuvash0.037082See
ISRIsrael Moroccan Jews0.0360113See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.036096See
SDNSudan Khartoum0.035798See
DZAAlgeria pop 27.00.0356106See
ESPSpain, Castilla y Leon, Northwest,6.50.03521743See
MKDMacedonia pop 30.0350172See
BRABrazil Parana Caucasian6.90.03502775See
PRTAzores Terceira Island0.0350130See
ITAItaly Rome7.00.0350100See
GRCGreece pop 70.035011250See
FRAFrance Bordeaux6.90.0344990See
MEXMexico Coahuila, Saltillo0.034272See
MEXMexico Colima Rural0.034143See
ROMRomania pop 36.70.03381469See
MEXMexico Zacatecas, Fresnillo0.0333103See
ARMArmenia Shirak0.033076See
FRAFrance Marseille6.60.03291000See
ITAItaly Lombardy6.40.0320674See
USAUSA OPTN Hispanic0.03201580See
SVKSlovakia pop 20.03164234See
ECUEcuador Coast Mixed Ancestry0.0315238See
MEXMexico Chihuahua Rural0.0314236See
MEXMexico Coahuila, Torreon0.0313396See
MKDMacedonia MBMDR - Albanian6.30.0313128See
SVNSlovenia pop 36.20.0310130See
ARMArmenia Ghegharkunik0.0310242See
AREUnited Arab Emirates pop 26.20.0310373See
ITAItaly North Pavia pop 26.20.03102416See
MEXMexico Guanajuato Rural0.0307162See
IRQIraq Arabs6.00.0302149See
MEXMexico Baja Californa, Mexicali0.0300100See
ENGEngland London Ashkenazi Jews0.0300500See
ROMRomania pop 20.03006936See
GRCGreece North0.0300500See
RUSRussia Arkhangelsk Pomor0.030063See
ISRIsrael Jews pop 26.00.030023000See
BRABrazil Parana Oriental6.10.030033See
SRBSerbia Vojvodina6.00.0300400See
FRAFrance Lyon6.00.02984813See
MEXMexico Zacatecas Rural0.0297266See
MEXMexico Chihuahua Chihuahua City0.0294119See
MEXMexico Mexico City South0.028852See
IRNIran pop 40.0287855See
MEXMexico Jalisco, Tonala0.028635See
FRAFrance Rennes pop 45.70.02851000See
RUSRussia Moscow0.02802650See
MKDMacedonia pop 40.0280216See
ARGArgentina Buenos Aires5.20.0280466See
CAFCentral African Republic Mbenzele Pygmy5.50.027836See
RUSRussia North Ossetian5.50.0276127See
MEXMexico Jalisco, Guadalajara city0.02721189See
MEXMexico Jalisco, Zapopan0.0268168See
MEXMexico Michoacan, Morelia0.0265150See
ENGEngland North West Mixed pop 25.30.0264379See
MKDMacedonia MBMDR - Macedonian Muslims5.30.026376See
CHLChile Santiago0.0261920See
MEXMexico Mestizo pop 40.0260269See
ARGArgentina Cuyo Region5.10.0260420See
ESPSpain North Cabuerniga0.026095See
MEXMexico Guanajuato, Leon0.025678See
ALBAlbania pop 25.10.0255432See
POLPoland pop 35.00.02512907See
AUSAustralia West Caucasian4.90.0250891See
ARGArgentina Buenos Aires pop 25.10.02501216See
FRAFrance Reims0.0250102See
FRAFrance Grenoble, Nantes and Rennes0.02506094See
MEXMexico Sinaloa Capomos Mayo Yoremes0.025060See
MEXMexico Tabasco Rural0.0246142See
MEXMexico Durango Rural0.0245326See
RUSRussia Samara Region0.02402500See
ISRIsrael Ashkenazi Jews pop 20.0240132See
MKDMacedonia MBMDR - Macedonian4.70.02381283See
MEXMexico Chihuahua, Ciudad Juarez0.0231106See
MEXMexico Veracruz Rural0.0231539See
RUSRussia Moscow Pop 24.60.02292000See
MEXMexico Michoacan Rural0.0229348See
MEXMexico Nuevo Leon Rural0.0227439See
SRBSerbia pop 34.40.02231992See
BIHBosnia and Herzegovina0.0223134See
MEXMexico Jalisco Rural0.0222585See
MEXMexico Veracruz, Poza Rica0.022245See
RUSRussia South Ural Russian4.30.0220207See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks4.50.0220112See
USAUSA OPTN Caucasian0.02208525See
PRTPortugal Center pop 20.0220562See
ESPSpain Minorca0.022094See
BOLBolivia Quechua0.021769See
MEXMexico Tamaulipas, Ciudad Victoria0.021723See
SDNSudan South Nuba4.30.021746See
ITAItaly pop 64.40.0217184See
ENGEngland Newcastle4.20.02122739See
INDIndia Kerala Hindu Ezhava0.021024See
MNGMongolia Tsaatan0.0210144See
MEXMexico Mexico City Mestizo0.0210121See
GRCGreece pop34.10.0207246See
ENGEngland Sheffield4.10.02074755See
MEXMexico Chiapas Rural0.0207121See
MEXMexico Nayarit, Tepic0.020697See
MEXMexico Yucatan, Merida0.0205192See
IRNIran Royan Cord Blood Bank3.90.020015600See
GBRUnited Kingdom pop 20.0200101See
PERPeru Arequipa Mestizo4.10.0200168See
GTMGuatemala, Guatemala City Mixed Ancestry3.90.0197127See
RUSRussia South Ural Tatar3.70.0190135See
MEXMexico Mexico City East0.018879See
ENGEngland Lancaster3.70.0186545See
MEXMexico Hidalgo Rural0.018581See
GBRUnited Kingdom South West0.0184163See
MEXMexico Sinaloa Mestizo0.018056See
ESPSpain North Cantabria0.018083See
MEXMexico Veracruz, Cordoba0.017956See
MEXMexico Zacatecas, Zacatecas city0.017984See
ECUEcuador Mixed Ancestry0.01711173See
RUSRussia South Ural Bashkir3.40.0170146See
KURIraq Kurdistan Region3.30.0170209See
DEUGermany Essen3.50.0170174See
BOLBolivia La Paz Aymaras0.017087See
MEXMexico Jalisco, Tlajomulco0.016730See
MEXMexico San Luis Potosi, San Luis Potosi city0.016730See
GBRUnited Kingdom North0.0166330See
IRQIraq Erbil3.20.0162372See
MEXMexico Mexico City Center0.0162152See
MEXMexico Durango, Durango city0.0161153See
ENGEngland Leeds3.20.01615024See
ESPSpain Pas Valley0.016088See
CHNChina Yunnan Province Han pop 20.0160129See
MEXMexico Aguascalientes state0.015895See
MEXMexico Puebla Rural0.0156833See
MEXMexico Nayarit Rural0.015664See
MEXMexico Nuevo Leon, Monterrey city0.0155226See
MEXMexico Sonora, Hermosillo0.015299See
RUSRussia Northwest3.00.01511011See
ENGEngland Manchester3.00.01511640See
MNGMongolia Khalkha0.0150200See
GBRUnited Kingdom Central0.0150135See
SWESweden pop 43.00.0150966See
WALWales pop 22.90.015039979See
RUSRussia Northwest pop 33.00.0150100See
TURTurkey pop 50.0140142See
ENGEngland Liverpool2.70.01351343See
NORNorway ethnic Norwegians2.60.01354510See
ECUEcuador Andes Mixed Ancestry0.0134824See
INDIndia North Gujarat2.70.0133338See
MEXMexico Oaxaca Rural0.0133485See
ARGArgentina Corrientes2.60.0130155See
ESPSpain Arratia Valley Basque0.013083See
PAKPakistan Mixed Sindhi0.0130101See
ECUEcuador Amazonia Mixed Ancestry0.012839See
MEXMexico Jalisco, Tlaquepaque0.012839See
MEXMexico Sonora Rural0.0127197See
IRLIreland South pop 20.012617624See
GBRUnited Kingdom East0.0123163See
MEXMexico Morelos, Cuernavaca0.012282See
COLColombia San Basilio de Palenque0.012042See
FRAFrance Southeast2.30.0120130See
MNGMongolia Ulaanbaatar Khalkha0.012041See
INDIndia Kerala Hindu Nair0.012041See
MEXMexico Mexico City Mestizo pop 30.0120256See
MEXMexico Queretaro Rural0.011643See
MEXMexico Coahuila Rural0.0115216See
MEXMexico Yucatan Rural0.0112132See
MEXMexico Puebla, Puebla city0.01101994See
SWESweden Stockholm2.10.01101347See
MEXMexico Veracruz, Xalapa0.0107187See
MEXMexico Guerrero state0.0104144See
MEXMexico Quintana Roo, Cancun0.010448See
RUSRussia Northwest pop 22.00.0100346See
MEXMexico Veracruz, Coatzacoalcos0.008955See
MEXMexico Mexico City North0.0086751See
MEXMexico Veracruz, Orizaba0.008360See
INDIndia North pop 30.0080587See
BRABrazil Parana Japanese2.00.0080192See
MEXMexico Tlaxcala Rural0.0072830See
BGDBangladesh Dhaka Bangalee0.0070141See
MEXMexico Baja California, La Paz0.006775See
MEXMexico Mexico City Metropolitan Area Rural0.0066150See
PERPeru Lamas City Lama0.006083See
MEXMexico Sinaloa Rural0.0055183See
MNGMongolia Khalkha pop 20.0050202See
SWESweden Uppsala1.00.0050300See
ESPSpain Majorcans Jews0.0050103See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.005094See
MEXMexico Sinaloa, Culiacán0.0049103See
HRVCroatia pop 30.80.0042120See
CHNChina Shaanxi Province Han0.004010000See
USAUSA OPTN Asian0.0040261See
RUSRussia Nenet Mixed0.004055See
MEXMexico Sonora, Ciudad Obregón0.0035143See
INDIndia sub-Himalayan West Bengal Kami0.60.0032158See
CHNChina Shandong Province0.50.00307418See
MYSMalaysia pop 30.00301445See
CHNChina Jiangsu Province0.003020248See
CHNChina Shanghai0.002026266See
CHNChina Harbin Korean0.0020201See
THAThailand pop 40.001016807See
KORSouth Korea pop 80.00007096See
MEXMexico Oaxaca, Oaxaca city0.0000151See
MEXMexico Mexico City West0.000033See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
GBRUnited Kingdom Orkney0.000088See
CHNChina Harbin Manchu0.0000172See
JPNJapan Hyogo Osaka and Nagano0.0000195See
MNGMongolia Hoton0.000085See
PAKPakistan Karachi Parsi0.000091See
CHNChina North Han0.0000105See
MNGMongolia Tarialan Khoton0.000085See
MEXMexico Huasteca Region Teenek0.000055See
ARGArgentina Rosario Toba0.00.000086See
ARGArgentina Chiriguano0.00.000054See
ARGArgentina Salta Wichi pop 20.00.000019See
KORSouth Korea pop 10.0000324See
RUSRussia Murmansk Saomi Mixed0.000070See
SCOScotland Orkney0.00.000099See
PAKPakistan Burusho0.000092See
TTOTrinidad South Asian0.000087See
MYSMalaysia pop 20.000062See
INDIndia Kerala Syrian Christian0.000031See
INDIndia Kerala Hindu Pulaya0.000016See
INDIndia Kerala Malabar Muslim0.000034See
INDIndia Kerala Hindu Namboothiri0.000040See
SAUSaudi Arabia0.00.000018See
CMRCameroon Bakola Pygmy0.00.000050See
CHNChina Yunnan Province Naxi0.0000118See
CHNChina Guangdong Province0.00.0000403See
MYSMalaysia Negeri Sembilan Minangkabau0.000034See
MYSMalaysia Perak Rawa0.000023See
MEXMexico Baja California Rural0.000050See
MEXMexico Campeche Rural0.000047See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Colima, Colima city0.000061See
MEXMexico Guanajuato, Guanajuato city0.000022See

See also higher resolution data of this allele

Allele  Number of Populations 
 A*23:01 284 
 A*23:01:01 33 
 A*23:02 39 
 A*23:03 47 
 A*23:04 46 
 A*23:05 60 
 A*23:06 27 
 A*23:07N 10 
 A*23:09 11 
 A*23:10 19 
 A*23:11N 19 
 A*23:12 11 
 A*23:16 14 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

Valid XHTML 1.0 Transitional