Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 421 time(s) and present in 413 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ESPSpain Andalusia Romani0.279099See
ISRIsrael Moroccan Jews0.2590113See
IRLIreland South pop 20.235917624See
CZECzech Republic Romani pop 241.30.217446See
ENGEngland Lancaster38.30.2145545See
GBRUnited Kingdom pop 20.2050101See
WALWales pop 235.50.197039979See
ENGEngland Sheffield35.50.19684755See
ENGEngland Liverpool35.10.19431343See
ENGEngland Newcastle34.80.19252739See
INDIndia North Gujarat35.50.1923338See
ESPSpain Arratia Valley Basque0.192083See
GBRUnited Kingdom Central0.1910135See
ENGEngland Leeds34.50.19065024See
ENGEngland Manchester34.30.18941640See
AUSAustralia West Caucasian33.60.1850891See
GBRUnited Kingdom Orkney0.182988See
RUSRussia South Ural Russian31.90.1810207See
GBRUnited Kingdom North0.1770330See
MEXMexico Campeche, Campeche city0.176534See
GBRUnited Kingdom East0.1718163See
SCOScotland Orkney33.00.170099See
GBRUnited Kingdom South West0.1687163See
ENGEngland North West Mixed pop 233.50.1676379See
CZECzech Republic Kurd29.70.162274See
FRAFrance Rennes pop 30.1600200See
NORNorway ethnic Norwegians29.30.15924510See
ESPSpain Majorcans Jews0.1590103See
ISRIsrael Ashkenazi Jews pop 20.1580132See
HRVCroatia pop 20.1570100See
USAUSA OPTN Caucasian0.15708525See
FRAFrance Reims0.1570102See
ALBAlbanian Kosovo0.1542120See
NORNorway pop 20.1520576See
ISRIsrael Jews pop 228.00.152023000See
FRAFrance Southeast27.70.1500130See
ARMArmenia living in Iran0.147085See
BIHBosnia and Herzegovina pop 229.20.1458120See
POLPoland pop 329.20.14582907See
DEUGermany Essen25.90.1440174See
MNGMongolia Oold0.1440104See
SVKSlovakia pop 20.14384234See
SRBSerbia pop 326.30.14261992See
RUSRussia Arkhangelsk Pomor0.140063See
SWESweden pop 426.10.1392966See
ESPSpain Ibiza0.138088See
MKDMacedonia pop 30.1370172See
MKDMacedonia MBMDR - Albanian25.80.1367128See
SWESweden Stockholm25.70.13601347See
ESPSpain Gipuzkoa Basque0.1350100See
AUTAustria Cord Bloods0.13501368See
SRBSerbia Vojvodina25.20.1350400See
BIHBosnia and Herzegovina0.1343134See
HRVCroatia pop 326.70.1333120See
BFABurkina Faso Fulani0.133049See
PAKPakistan Mixed Sindhi0.1330101See
MKDMacedonia MBMDR - Macedonian24.40.13211283See
KURIraq Kurdistan Region23.90.1320209See
FRAFrance Grenoble, Nantes and Rennes0.13206094See
SWESweden Uppsala24.30.1299300See
FRAFrance Grenoble25.90.12981000See
ARMArmenia living in USA0.1290233See
ROMRomania pop 324.10.12881469See
ARMArmenia Lori0.1270102See
FRAFrance Rennes pop 425.20.12661000See
FRAFrance Lyon25.30.12644813See
PRTPortugal Leiria0.12601847See
ENGEngland London Ashkenazi Jews0.1260500See
MKDMacedonia MBMDR - Macedonian Muslims25.00.125076See
MNGMongolia Tsaatan0.1250144See
IRNIran pop 10.125064See
ARMArmenia Syunik0.1240117See
PRTPortugal Castelo Branco0.1240327See
GAZGaza Palestinians0.1240165See
FRAFrance Marseille24.70.12351000See
BRABrazil Parana Afro Brazilian24.70.123077See
DZAAlgeria pop 223.00.1225106See
ITAItaly pop 623.90.1223184See
VENVenezuela Colonia Tovar0.122186See
RUSRussia Northwest pop 222.90.1220346See
FRAFrance Bordeaux24.30.1219990See
ITAItaly Rome24.00.1200100See
GRCGreece Crete0.1200135See
ROMRomania pop 20.12006936See
PRTPortugal Coimbra0.12005057See
PRTPortugal Braga0.12001971See
RUSRussia Moscow Pop 222.30.11942000See
RUSRussia Northwest22.40.11901011See
ARGArgentina Buenos Aires23.20.1190466See
RUSRussia North Ossetian22.80.1181127See
RUSRussia South Ural Tatar22.20.1180135See
ARMArmenia Ghegharkunik0.1180242See
ITAItaly Lombardy22.10.1170674See
ARMArmenia living in Karabakh0.1160445See
IRNIran Royan Cord Blood Bank21.90.116015600See
PRTPortugal Viseu0.11502915See
ARGArgentina La Plata22.00.1150100See
ESPSpain Andalusia0.114099See
RUSRussia Moscow0.11402650See
ITAItaly North Pavia pop 30.1136685See
ARMArmenia living in Lebanon0.1130368See
PRTPortugal South pop 20.11301021See
MKDMacedonia pop 40.1130216See
BRABrazil Curitiba-Parana Mixed0.1127264See
PRTPortugal North pop 20.11211801See
ARMArmenia Shirak0.112076See
ITAItaly North Pavia pop 221.10.11202416See
PRTPortugal Porto0.11107937See
BRABrazil REDOME Santa Catarina0.1110106673See
IRQIraq Arabs22.10.1107149See
ITAItaly East Sicily18.00.110050See
TTOTrinidad South Asian0.110087See
MARMorocco Casablanca0.1100100See
TUNTunisia Ghannouch0.110082See
RUSRussia Tatars0.1098355See
ESPSpain Sevilla21.20.1097278See
PRTPortugal Vila Real0.10901167See
PRTAzores Terceira Island0.1090130See
PRTPortugal Center pop 20.1090562See
TURTurkey pop 50.1090142See
IRQIraq Erbil21.80.1090372See
IRNIran pop 40.1088855See
BRABrazil REDOME Rio Grande do Sul0.1083241329See
PRTPortugal Aveiro0.10805933See
ESPSpain North Cantabria0.108083See
INDIndia Bikaner Non-Raikas20.40.1080127See
PRTPortugal Santarem0.10703865See
PRTPortugal Lisbon0.107017420See
ARMArmenia Yerevan0.1070445See
ESPSpain, Castilla y Leon, Northwest,19.40.10631743See
PRTPortugal Portalegre0.10601254See
PRTMadeira pop 30.1060538See
PRTPortugal Guarda0.1060797See
ESPSpain Majorca0.1060407See
BRABrazil Rio Grande do Sul Caucasoid0.10504428See
GRCGreece pop 70.104911250See
PRTPortugal Setubal0.10405268See
INDIndia Kerala Hindu Ezhava0.104024See
RUSRussia Samara Region0.10302500See
CHLChile Santiago0.1027920See
ARGArgentina Buenos Aires pop 219.30.10101216See
GRCGreece North0.1000500See
MARMorocco pop 20.1000110See
RUSRussia Transbaikal Territory Buryats20.00.1000150See
BRABrazil REDOME Parana0.0998341639See
BRABrazil Parana Caucasian19.70.09902775See
MEXMexico Durango Rural0.0979326See
MEXMexico Hidalgo, Pachuca0.097641See
ALBAlbania pop 218.30.0972432See
PRTPortugal Faro0.09701242See
ITAItaly South Campania Region18.40.09661089See
BRABrazil Paraná Caucasian19.00.0959641See
MEXMexico Tamaulipas Rural0.0952125See
ESPSpain Murcia0.0950173See
BGDBangladesh Dhaka Bangalee0.0950141See
RUSRussia Northwest pop 317.00.0950100See
MEXMexico Sonora, Ciudad Obregón0.0944143See
BRABrazil REDOME Sao Paulo0.0942800809See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks18.80.0940112See
MEXMexico Durango, Durango city0.0935153See
SVNSlovenia pop 317.70.0930130See
BRABrazil South Ribeirao Preto0.0930184See
ESPSpain Majorca and Minorca0.093090See
BRABrazil REDOME Goias0.092788574See
BRABrazil Parana Cafuzo18.50.0920319See
GRCGreece pop317.50.0917246See
PRTPortugal Viana do Castelo0.0910706See
PRTPortugal Beja0.0910699See
BRABrazil REDOME Mato Grosso0.090734649See
MEXMexico Zacatecas, Fresnillo0.0905103See
BRABrazil REDOME Minas Gerais0.0900211275See
PRTPortugal Bragança0.0900301See
BRABrazil REDOME Espirito Santo0.089788485See
MEXMexico Aguascalientes state0.089595See
PRTMadeira pop 20.0890173See
RUSRussia South Ural Bashkir17.80.0890146See
ARGArgentina Cuyo Region17.10.0890420See
BRABrazil REDOME Federal District0.088529549See
BRABrazil REDOME Mato Grosso do Sul0.088295667See
BRABrazil REDOME Rondonia0.088154396See
BRABrazil South East Cord Blood0.088111409See
BRABrazil Sao Paulo Bauru Mixed0.08803542See
BRABrazil REDOME Rio Grande do Norte0.087346603See
SAUSaudi Arabia16.70.087318See
BRABrazil REDOME Alagoas0.087225349See
MEXMexico Coahuila Rural0.0872216See
BRABrazil Rio Grande do Norte Mestizo0.087012973See
BRABrazil Rio Grande do Sul Mixed0.0870324See
BRABrazil REDOME Paraiba0.086243868See
INDIndia North pop 30.0860587See
PRTPortugal Evora0.0860737See
ESPSpain Catalonia Girona0.086088See
GEOGeorgia Kurds0.086030See
MEXMexico Jalisco, Tonala0.085735See
BRABrazil REDOME Rio de Janeiro0.0857139322See
MEXMexico Veracruz, Xalapa0.0856187See
BRABrazil REDOME Acre0.0850859See
MNGMongolia Ulaanbaatar Khalkha0.085041See
INDIndia Kerala Hindu Nair0.085041See
MEXMexico Mestizo14.60.085041See
BRABrazil Pernambuco Mixed0.0840101See
ARGArgentina Corrientes14.80.0840155See
BRABrazil REDOME Ceara0.0835101217See
MEXMexico Morelos Rural0.083330See
MEXMexico Mexico City Mestizo0.0830121See
GTMGuatemala, Guatemala City Mixed Ancestry16.50.0827127See
BRABrazil REDOME Sergipe0.08127321See
BRABrazil REDOME Pernambuco0.081092332See
BRABrazil Minas Gerais State Mixed15.30.08101000See
ARGArgentina Rosario Toba16.30.081086See
MNGMongolia Khalkha0.0800200See
ITAItaly North Pavia0.080081See
CUBCuba Mixed0.080078See
MEXMexico Baja California, Tijuana0.080025See
BRABrazil REDOME Maranhao0.079810180See
BRABrazil REDOME Tocantins0.079320692See
INDIndia Bikaner Raikas15.10.0790143See
MEXMexico Michoacan Rural0.0774348See
TUNTunisia pop 30.0770104See
SDNSudan East Rashaida14.80.076927See
MEXMexico Guanajuato, Leon0.076978See
MMRMyanmar Bamar13.00.076146See
ESPSpain North Cabuerniga0.076095See
ITAItaly Bergamo14.90.0750101See
MNGMongolia Khalkha pop 20.0750202See
BRABrazil REDOME Bahia0.074647399See
RUSRussia Chuvash0.073082See
BRABrazil REDOME Piaui0.072146140See
MEXMexico Mexico City Center0.0714152See
BRABrazil Piaui Mixed0.071021943See
CUBCuba Mixed Race14.30.071042See
SAUSaudi Arabia pop 413.60.0701499See
VENVenezuela Caracas Mestizo0.070050See
MEXMexico Baja California Rural0.070050See
MEXMexico Tapachula, Chiapas Mestizo Population13.90.069472See
MEXMexico Zacatecas Rural0.0688266See
MEXMexico Jalisco, Guadalajara city0.06871189See
SAUSaudi Arabia pop 20.0680383See
BRABrazil REDOME Roraima0.06754140See
BRABrazil Para State15.10.06725000See
MEXMexico Tabasco, Villahermosa0.067182See
CUBCuba Mixed pop 20.0670189See
BRABrazil Sao Paulo Mixed13.00.0670239See
MEXMexico Veracruz, Orizaba0.066760See
MEXMexico San Luis Potosi, San Luis Potosi city0.066730See
MEXMexico Baja California, La Paz0.066775See
MEXMexico Coahuila, Torreon0.0663396See
TURTurkey pop 20.0660228See
MNGMongolia Tarialan Khoton0.066085See
MNGMongolia Hoton0.066085See
BRABrazil REDOME Amazonas0.065924129See
MEXMexico Colima, Colima city0.065661See
MEXMexico Tamaulipas, Ciudad Victoria0.065223See
MEXMexico Baja Californa, Mexicali0.0650100See
NORNorway Sami0.0650200See
FRAFrance Corsica Island0.0650100See
MEXMexico Guanajuato Rural0.0644162See
BRABrazil REDOME Para0.063872637See
MEXMexico Tlaxcala, Tlaxcala city0.0635181See
INDIndia Kerala Hindu Namboothiri0.063040See
USAUSA OPTN Hispanic0.06301580See
AREUnited Arab Emirates pop 212.10.0620373See
MEXMexico Jalisco Rural0.0614585See
MEXMexico Mestizo pop 40.0613269See
TTOTrinidad African0.060067See
ESPSpain Minorca0.060094See
MEXMexico Quintana Roo Rural0.060050See
COLColombia San Basilio de Palenque0.060042See
BRABrazil REDOME Amapa0.059917864See
INDIndia Kerala Malabar Muslim0.059034See
MEXMexico Chihuahua Rural0.0586236See
MEXMexico Chiapas, Tuxtla Gutierrez0.056652See
SDNSudan Khartoum0.056398See
MEXMexico Veracruz, Poza Rica0.055645See
USAUSA OPTN African American0.05501510See
MEXMexico Morelos, Cuernavaca0.054982See
BRABrazil Para Cord Blood Unit10.60.0547841See
PAKPakistan Burusho0.054092See
MEXMexico Sinaloa Mestizo0.054056See
MEXMexico Yucatan Rural0.0522132See
MEXMexico Veracruz Rural0.0518539See
MEXMexico Nayarit, Tepic0.051597See
MEXMexico Jalisco, Tlaquepaque0.051339See
BRABrazil Parana Mixed race10.20.0510186See
MEXMexico Nuevo Leon, Monterrey city0.0509226See
MEXMexico Jalisco, Zapopan0.0506168See
MEXMexico Jalisco, Tlajomulco0.050030See
MEXMexico Sinaloa Rural0.0492183See
COLColombia Barranquilla0.0480188See
INDIndia Kerala Syrian Christian0.048031See
MEXMexico Zacatecas, Zacatecas city0.047684See
BFABurkina Faso Mossi0.047053See
MMRMyanmar Mon9.40.046964See
MEXMexico Queretaro Rural0.046543See
MEXMexico Michoacan, Morelia0.0464150See
MEXMexico Tabasco Rural0.0458142See
MEXMexico Guanajuato, Guanajuato city0.045522See
ITAItaly Sardinia pop30.0450100See
CHNChina Harbin Manchu0.0450172See
CHNChina Shaanxi Province Han0.045010000See
SDNSudan South Nuba8.70.044446See
MEXMexico Veracruz, Veracruz city0.0436171See
BOLBolivia Quechua0.043569See
MEXMexico Hidalgo Rural0.043281See
MEXMexico Sonora Rural0.0431197See
MEXMexico Mexico City Mestizo pop 30.0430256See
ECUEcuador Coast Mixed Ancestry0.0420238See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.042096See
BRABrazil Rio Grande do Sul Black0.0420248See
MEXMexico Chihuahua, Ciudad Juarez0.0417106See
ECUEcuador Andes Mixed Ancestry0.0413824See
MEXMexico Coahuila, Saltillo0.041172See
MEXMexico Yucatan, Merida0.0410192See
CHNChina Shandong Province8.10.04107418See
PERPeru Arequipa Mestizo8.10.0410168See
ZAFSouth Africa Natal Zulu8.00.0400100See
RUSRussia Murmansk Saomi Mixed0.040070See
MEXMexico Oaxaca, Oaxaca city0.0397151See
MEXMexico Sinaloa, Culiacán0.0388103See
ECUEcuador Mixed Ancestry0.03841173See
ESPSpain Pas Valley0.038088See
MEXMexico Mexico City Metropolitan Area Rural0.0362150See
MEXMexico Veracruz, Cordoba0.035756See
MEXMexico Veracruz, Coatzacoalcos0.035755See
MEXMexico Sonora, Hermosillo0.035499See
MEXMexico Tlaxcala Rural0.0349830See
MEXMexico San Luis Potosi Rural0.034587See
MEXMexico Puebla Rural0.0330833See
JPNJapan Hyogo6.30.033032See
MEXMexico Puebla, Puebla city0.03211994See
BFABurkina Faso Rimaibe0.032047See
USAUSA OPTN Asian0.0320261See
CHNChina Jiangsu Province0.031020248See
RUSRussia Nenet Mixed0.031055See
MEXMexico Oaxaca Rural0.0308485See
CMRCameroon Bakola Pygmy6.00.030450See
MEXMexico Mexico City West0.030333See
TWNTaiwan Chinese immigrants from North China0.0300152See
MYSMalaysia Negeri Sembilan Minangkabau0.030034See
VNMVietnam Hanoi0.030050See
MEXMexico Puebla Mestizo0.030099See
MEXMexico Chihuahua Chihuahua City0.0294119See
MEXMexico Mexico City South0.028852See
MMRMyanmar Shan5.60.027854See
MEXMexico Nuevo Leon Rural0.0273439See
CMRCameroon Ewondo0.026038See
GHAGhana Accre Asutuare Akan0.0260429See
INDIndia sub-Himalayan West Bengal Kami5.10.0253158See
INDIndia Jalpaiguri Toto5.00.025340See
VENVenezuela Zulia Maracaibo Mixed0.025020See
VENVenezuela Zulia San Jose de Heras Mixed0.025020See
MEXMexico Mexico City East0.025079See
MEXMexico Chiapas Rural0.0248121See
THAThailand Northeast0.024066See
CHNChina Shanghai0.024026266See
MEXMexico Nayarit Rural0.023464See
MEXMexico Colima Rural0.022743See
MEXMexico Mexico City North0.0226751See
MEXMexico Queretaro, Queretaro city0.022245See
GTMGuatemala Mayan0.0220132See
JPNJapan Aichi4.40.022050See
THAThailand pop 40.022016807See
MEXMexico Campeche Rural0.021347See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.021094See
MYSMalaysia pop 30.02101445See
MEXMexico Guerrero state0.0208144See
ARGArgentina Chiriguano3.80.019054See
KORSouth Korea pop 80.01907096See
CHNChina Wuhan3.30.0170121See
THAThailand Northeast pop 20.0160400See
BRABrazil Parana Japanese3.00.0156192See
TWNTaiwan Chinese immigrants from South China0.0150172See
CHNChina Harbin Korean0.0150201See
CMRCameroon Uldeme0.014035See
CHNChina Guangdong Province2.70.0135403See
ECUEcuador Amazonia Mixed Ancestry0.012839See
MYSMalaysia pop 20.012062See
PERPeru Lamas City Lama0.012083See
ZAFSouth Africa Tswana2.50.012041See
CMRCameroon Podokwo0.012043See
CHNChina Shandong Province Linqu County2.20.0110139See
KORSouth Korea pop 10.0110324See
BOLBolivia La Paz Aymaras0.011087See
MEXMexico Quintana Roo, Cancun0.010448See
JPNJapan Hyogo Osaka and Nagano0.0100195See
MYSMalaysia Sarawak Iban0.010051See
MMRMyanmar Chin1.80.009155See
MMRMyanmar Kayah1.80.009155See
JPNJapan Kyoto and Osaka0.0090165See
RUSRussia Sakhalin Island Nivkhi0.009053See
TWNTaiwan Chinese immigrants from Middle China0.0090211See
MEXMexico Sinaloa Capomos Mayo Yoremes0.008360See
JPNJapan pop 111.60.008062See
JPNJapan pop 20.0040916See
TWNTaiwan Minnan pop 20.00307137See
TWNTaiwan Minnan and Hakka0.0030190See
TWNTaiwan Hakka pop 20.0020714See
BRABrazil Parana Oriental0.00.000033See
CHNChina North Han0.0000105See
INDIndia Kerala Hindu Pulaya0.000016See
TWNTaiwan Aborigine0.0000111See
MEXMexico Huasteca Region Teenek0.000055See
ARGArgentina Salta Wichi pop 20.00.000019See
CMRCameroon Bamileke 20.000035See
MYSMalaysia Perak Rawa0.000023See

See also higher resolution data of this allele

Allele  Number of Populations 
 A*01:01:01:01 21 
 A*01:12 16 
 A*01:17 24 
 A*01:18N 13 
 A*01:10 13 
 A*01:07 17 
 A*01:09 28 
 A*01:08 15 
 A*01:04N 14 
 A*01:01 303 
 A*01:16N 16 
 A*01:02 156 
 A*01:11N 15 
 A*01:23 11 
 A*01:25 20 
 A*01:14 12 
 A*01:01:01 51 
 A*01:13 13 
 A*01:03 113 
 A*01:36 18 
 A*01:06 62 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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