Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 218 time(s) and present in 172 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
PNGPapua New Guinea Lowland0.208047See
KENKenya, Nyanza Province, Luo tribe34.00.1850100See
COLColombia Providencia Island African0.183030See
RWARwanda Kigali Hutu and Tutsi0.1680281See
ZWEZimbabwe Harare Shona0.1530230See
COLColombia West Cauca0.150020See
CRICosta Rica African -Caribbean (G)27.40.1470102See
USAUSA NMDP Caribean Black0.136733328See
USAUSA Colorado Univ Cord Blood Bank African American0.1310261See
COLColombia Northwest Choco0.125020See
USAUSA NMDP African0.125028557See
USAUSA African American pop 30.1220564See
USAUSA African American pop 70.1220193See
CAFCentral African Republic Aka Pygmy22.60.120093See
USAUSA African American pop 40.11752411See
USAUSA NMDP African American pop 20.1166416581See
STPSao Tome Island Forro0.110066See
STPSao Tome Island Angolar0.109032See
ISRIsrael Ethiopian Jews0.1040122See
ISRIsrael Ethiopia Jews0.09905928See
ETHEthiopia Amhara0.092098See
USAUSA African American Bethesda16.90.0920187See
ETHEthiopia Oromo0.090083See
TZATanzania Maasai14.10.0856336See
ZAFSouth Africa Worcester16.00.0820159See
GNQEquatorial Guinea Bioko Island Bubi0.0630100See
COLColombia San Basilio de Palenque0.060042See
SDNSudan Mixed11.50.0600200See
BRABrazil Mixed0.0450108See
TUNTunisia pop 30.0390104See
COLColombia Sierra Nevada de Santa Marta Ijka pop 20.033030See
NICNicaragua Mestizo (G)6.60.0330155See
USAUSA NMDP Caribean Indian0.033014339See
CRICosta Rica Guanacaste Mestizo (G)5.50.0320110See
COLColombia North Chimila Amerindians0.031947See
INDIndia Northeast Mathur0.0300155See
IDNIndonesia Singaporean0.030050See
BRABrazil Mato Grosso do Sul0.0270203See
USAUSA NMDP Caribean Hispanic0.0267115374See
BRABrazil North East Mixed0.0250205See
MYSMalaysia Kedah Kensiu4.80.024021See
BOLBolivia/Peru Quechua NA-DHS_12 (G)4.80.023821See
NICNicaragua Managua4.20.0225339See
SENSenegal Dakar4.40.0220112See
AREUnited Arab Emirates Pop 10.0220570See
INDIndia Northeast Kayastha0.0210190See
GAZGaza Palestinians0.0210165See
COLColombia North Wiwa El Encanto0.019252See
BRABrazil Southeast Caucasian3.90.0190103See
MYSMalaysia Mandailing3.70.019027See
INDIndia Northeast Rastogi0.0180196See
USAUSA South Texas Hispanic0.0180194See
INDIndia Northeast Vaish0.0170198See
MYSMalaysia Champa3.50.017029See
SAUSaudi Arabia Guraiat and Hail2.90.0170213See
USAUSA Spain Ancestry0.0160279See
MARMorocco Atlantic Coast Chaouya0.015098See
MARMorocco Settat Chaouya0.015098See
INDIndia Uttar Pradesh0.0150202See
ISRIsrael Arab pop 20.014712301See
COLColombia Bogotá Cord Blood2.80.01401463See
MEXMexico Mexico City Mestizo population0.0140143See
USAUSA San Diego2.60.0140496See
USAUSA NMDP Hispanic South or Central American0.0137146714See
USAUSA Southern California Mestizo2.70.013573See
USAUSA Mexican American Mestizo0.0120553See
BRABrazil Southeast Mixed Race2.40.012042See
MEXMexico Veracruz Xalapa2.40.011984See
BRABrazil Paraná Caucasian2.30.0117641See
USAUSA Hispanic pop 20.01131999See
ZAFSouth Africa Caucasians0.0110102See
POLPoland Wielkopolska Region0.010099See
MEXMexico Oaxaca Jamiltepec Mixtec0.010096See
MEXMexico Mixtec0.010097See
INDIndia Northeast Sunni0.0100188See
AREUnited Arab Emirates Abu Dhabi0.009652See
GMBGambia pop 31.90.0093939See
COLColombia Guajira Peninsula Wayuu0.009088See
USAUSA NMDP American Indian South or Central America0.00805926See
IRNIran Fars Parsi0.007073See
ARGArgentina Buenos Aires1.40.0070466See
CUBCuba Mixed0.007078See
MEXMexico Mazatecan0.007089See
BRABrazil South Caucasian0.006973See
MEXMexico Mexico City Mestizo pop 30.0060256See
MEXMexico Highlands Mestizos1.30.0060160See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.00601058See
USAUSA NMDP Mexican or Chicano0.0058261235See
USAUSA South Dakota Sioux0.0050101See
MEXMexico Guanajuato and Jalisco Mestizo1.00.0050101See
ITAItaly Rome1.00.0050100See
ISRIsrael Arab0.0050109See
MARMorocco Nador Metalsa0.005099See
FRAFrance West1.00.0050100See
INDIndia Northeast Shia0.0050190See
USAUSA Philadelphia Caucasian0.70.0040141See
TURTurkey pop 10.0040250See
USAUSA Mexican American Mestizo pop 30.0040116See
ECUEcuador Cayapa0.0030183See
PRTMadeira pop 20.0030173See
DEUGermany DKMS - France minority0.00281406See
CHLChile Santiago0.0027920See
USAUSA NMDP North American Amerindian0.002735791See
MEXMexico Mexico City Mestizo pop 20.0021234See
GRCGreece pop30.40.0020246See
USAUSA NMDP Alaska Native or Aleut0.00201376See
USAUSA Caucasian pop 50.0020268See
USAUSA Italy Ancestry0.0020273See
USAUSA Eastern European0.0020558See
USAUSA NMDP Middle Eastern or North Coast of Africa0.001970890See
DEUGermany DKMS - Spain minority0.00181107See
MEXMexico Mexico City Tlalpan0.30.0015330See
ISRIsrael YemenJews0.001215542See
ITAItaly pop 50.0010975See
NLDNetherlands Leiden0.00101305See
DEUGermany DKMS - Croatia minority0.00102057See
CHNChina Beijing Shijiazhuang Tianjian Han0.0010618See
USAUSA Caucasian pop 40.00101070See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00103830See
RUSRussia Karelia0.00091075See
CHESwitzerland Lausanne0.0009993See
ISRIsrael USA Jews0.00086058See
DEUGermany DKMS - Romania minority0.00081234See
USAUSA NMDP Hawaiian or other Pacific Islander0.000711499See
INDIndia Tamil Nadu0.00062492See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.10.00064335See
CHESwitzerland Luzern0.00061553See
USAUSA NMDP Southeast Asian0.000627978See
USAUSA Asian pop 20.00061772See
CHESwitzerland Sion0.0005832See
CHESwitzerland Lugano0.00051169See
ESPSpain Barcelona0.10.0005941See
DEUGermany DKMS - Turkey minority0.00054856See
HRVCroatia pop 40.00054000See
USAUSA NMDP European Caucasian0.00051242890See
CHESwitzerland Zurich0.00044875See
DEUGermany pop 80.000439689See
DEUGermany DKMS - Portugal minority0.00041176See
DEUGermany DKMS - Italy minority0.00041159See
DEUGermany DKMS - Netherlands minority0.00041374See
USAUSA NMDP Filipino0.000350614See
DEUGermany DKMS - German donors0.00033456066See
HKGHong Kong Chinese cord blood registry0.00033892See
ISRIsrael Argentina Jews0.00024307See
ISRIsrael Ashkenazi Jews pop 30.00024625See
INDIndia South UCBB0.00.000211446See
ISRIsrael Druze0.00025914See
USAUSA NMDP South Asian Indian0.0002185391See
ISRIsrael Libya Jews0.00013739See
HKGHong Kong Chinese BMDR0.00017595See
USAUSA NMDP Vietnamese0.000143540See
DEUGermany pop 60.00018862See
KORSouth Korea pop 100.00014128See
POLPoland DKMS0.000220653See
ISRIsrael Morocco Jews0.000136718See
INDIndia West UCBB0.00.00015829See
ISRIsrael USSR Jews0.000145681See
USAUSA NMDP Japanese0.000124582See
USAUSA NMDP Korean0.000077584See
ISRIsrael Iraq Jews0.000013270See
ISRIsrael Poland Jews0.000013871See
USAUSA NMDP Chinese0.000099672See
CHESwitzerland St Gallen0.00002113See
USAUSA Colorado Univ Cord Blood Bank Asian0.0000100See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian0.00.000061655See
USAUSA San Antonio Caucasian0.0000222See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA Caucasian Houston0.00.0000194See
USAUSA Caucasian Pittsburgh0.00.0000177See
ISRIsrael Yemenite Jews0.000076See
KORSouth Korea pop 20.00.0000207See
KORSouth Korea pop 30.0000485See
MKDMacedonia pop 10.0000158See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
ESPSpain Murcia0.0000173See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
PNGPapua New Guinea Lowland Wosera0.000079See
PNGPapua New Guinea Highland0.000094See
IRNIran Yazd Zoroastrian0.000065See
NIRIreland Northern0.00.00001000See
ISRIsrael Libyan Jews0.0000119See
ISRIsrael Iranian Jews0.0000101See
INDIndia Northeast Lachung0.000058See
INDIndia Northeast Mech0.000063See
INDIndia Northeast Rajbanshi0.000098See
IDNIndonesia Nusa Tenggara Islands0.000049See
IDNIndonesia Moluccan Islands0.000024See
CZECzech Republic0.0000106See
FRAFrance Rennes pop 30.0000200See
COLColombia Bogota and Medellin Mestizo0.000065See
CHNChina Urumqi Uyghur0.00.000057See
CANCanada British Columbia Athabaskan0.000062See
CANCanada British Columbia Penutian0.000026See
BRABrazil Guarani M bya0.000093See
BRABrazil Kaingang0.0000235See
BRABrazil Vale do Ribeira Quilombos0.10.0000144See
BRABrazil Guarani Nandeva0.000086See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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