Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 195 time(s) and present in 121 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
RUSRussia Siberia Sulamai Ket0.300022See
RUSRussia Siberia Polygus Evenk0.260035See
RUSRussia Sakhalin Island Nivkhi0.085053See
RUSRussia Siberia Ulchi0.068073See
RUSRussia Siberia Lower Yenisey Ket0.059017See
CHNChina, Xinjiang Uyghur Autonomous Region Hui11.80.058840See
MNGMongolia Oold0.0580104See
RUSRussia Siberia Irkutsk Tofalar0.047043See
CHNChina Yunnan Province Drung0.043070See
RUSRussia Siberia Dudinka Nganasan0.042024See
JPNJapan Aichi6.50.039050See
CHNChina Urumqi Kazak0.036042See
MNGMongolia Khalkha pop 20.0350202See
RUSRussia Tuva pop 20.0290169See
RUSRussia Tuva0.0250190See
JPNJapan pop 114.80.024362See
MNGMongolia Ulaanbaatar Khalkha0.024041See
CHNChina Yunnan Province Han pop 20.0230129See
RUSRussia Tuva Todja0.022022See
CHNChina Harbin Korean0.0200201See
CHNChina Yunnan Province Han0.0200101See
RUSRussia Siberia Kushun Buryat0.020025See
RUSRussia Siberia Khabarovsk Evenki0.020025See
RUSRussia Transbaikal Territory Buryats4.00.0200150See
RUSRussia Siberia North East Kamchatka Koryak0.020092See
JPNJapan pop 63.90.0196129See
JPNJapan Nagano3.50.017657See
JPNJapan pop 170.01663078See
JPNJapan pop 20.0160916See
CHNChina Inner Mongolia Region Ewenki0.016094See
JPNJapan pop 160.015718604See
JPNJapan Central0.0150371See
JPNJapan pop 42.90.0150525See
RUSRussia Siberia Khanty Mansi0.015068See
JPNJapan Hokkaido Wajin2.80.014171See
USAUSA NMDP Korean0.013277584See
JPNJapan Hyogo Osaka and Nagano0.0130195See
JPNJapan pop 30.01301018See
INDIndia Northeast Sunni0.0130188See
CHNChina, Xinjiang Uyghur Autonomous Region Han2.50.012570See
COLColombia San Basilio de Palenque0.012042See
JPNJapan Kyoto and Osaka0.0120165See
JPNJapan South2.40.0120125See
KORSouth Korea pop 22.40.0120207See
MNGMongolia Hoton0.012085See
MNGMongolia Tarialan Khoton0.012085See
RUSRussia Tuva pop30.011044See
KORSouth Korea pop 100.01104128See
INDIndia Northeast Kayastha0.0110190See
CHNChina, Xinjiang Uyghur Autonomous Region Uyghur2.20.010971See
CHNChina pop11.90.0100103See
INDIndia Uttar Pradesh0.0100202See
CHNChina Yunnan Province Naxi0.0090118See
CHNChina Harbin Manchu0.0090172See
CHNChina Urumqi Uyghur1.80.009057See
KORSouth Korea pop 30.0090485See
RUSRussia Siberia Eskimo0.009070See
MEXMexico Sinaloa Capomos Mayo Yoremes0.008360See
KORSouth Korea pop 60.0080800See
INDIndia Northeast Rastogi0.0080196See
INDIndia Northeast Vaish0.0080198See
KORSouth Korea pop 41.40.0070211See
KORSouth Korea pop 10.0060324See
CHNChina Beijing and Xian0.0060171See
CHNChina Hubei Han1.00.00513732See
IRNIran Azeri0.0050100See
CHNChina Xinjiang Province Uyghur0.005092See
CHNChina Shandong Province Han0.005098See
CHNChina Beijing Shijiazhuang Tianjian Han0.0050618See
CHNChina Yunnan Province Nu0.0050107See
MNGMongolia Khalkha0.0050200See
TWNTaiwan Minnan pop 11.00.0050102See
USAUSA Colorado Univ Cord Blood Bank Asian0.0050100See
CHNChina Jiangsu Han0.00483238See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0043233See
CHNChina Zhejiang Han pop 20.0042833See
CHNChina Canton Han0.0040264See
INDIndia Lucknow0.80.0040123See
DEUGermany DKMS - China minority0.00391282See
USAUSA Asian pop 20.00371772See
TWNTaiwan Tzu Chi Cord Blood Bank0.0030710See
TWNTaiwan Han Chinese0.0030504See
USAUSA Caucasian Houston0.60.0030194See
VNMVietnam Hanoi Kinh pop 20.0030170See
INDIndia Northeast Shia0.0030190See
KORSouth Korea pop 110.0030149See
USAUSA NMDP Chinese0.002599672See
TWNTaiwan Tzu Chi Morrow Donor Registry0.002346682See
HKGHong Kong Chinese cord blood registry0.00213892See
PRTAzores Terceira Island0.0020130See
CHNChina Jiangsu Province Han0.0018334See
NICNicaragua Managua0.30.0015339See
HKGHong Kong Chinese BMDR0.00147595See
CHNChina Marrow Donor Registry0.0010600See
USAUSA San Diego0.20.0010496See
USAUSA NMDP Alaska Native or Aleut0.00101376See
USAUSA Eastern European0.0010558See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.00101058See
DEUGermany DKMS - Turkey minority0.00074856See
USAUSA NMDP Hawaiian or other Pacific Islander0.000711499See
RUSRussia Karelia0.00051075See
USAUSA NMDP Vietnamese0.000543540See
DEUGermany DKMS - United Kingdom minority0.00051043See
USAUSA NMDP Southeast Asian0.000227978See
INDIndia Tamil Nadu0.00022492See
INDIndia South UCBB0.00.000211446See
USAUSA NMDP Filipino0.000250614See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000170890See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00013830See
CZECzech Republic NMDR0.00015099See
DEUGermany pop 80.000139689See
POLPoland DKMS0.000120653See
USAUSA NMDP South Asian Indian0.0001185391See
DEUGermany DKMS - German donors0.00013456066See
ISRIsrael USSR Jews0.000145681See
SAUSaudi Arabia pop 6 (G)0.000028927See
USAUSA NMDP European Caucasian0.00001242890See
USAUSA NMDP African0.000028557See
USAUSA NMDP Hispanic South or Central American0.0000146714See
USAUSA NMDP Mexican or Chicano0.0000261235See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
USAUSA Caucasian0.00.000061655See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Colorado Univ Cord Blood Bank African American0.0000261See
USAUSA Hispanic pop 20.00001999See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA African American pop 40.00002411See
USAUSA Caucasian Pittsburgh0.00.0000177See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
IRNIran Kurd0.0000100See
INDIndia Northeast Mathur0.0000155See
INDIndia Northeast Lachung0.000058See
INDIndia Northeast Mech0.000063See
INDIndia Northeast Rajbanshi0.000098See
ENGEngland pop 60.00.0000177See
ESPSpain Barcelona0.00.0000941See
ESPSpain Murcia0.0000173See
FRAFrance West0.00.0000100See
DEUGermany pop 60.00018862See
CHNChina Urumqi Han0.000059See
ARGArgentina Rio Negro Mapuche0.000034See
ARGArgentina Chubut Tehuelche0.000023See
ARGArgentina Salta Wichi0.000024See
BRABrazil North East Mixed0.0000205See
BRABrazil Kaingang0.0000235See
BRABrazil Guarani M bya0.000093See
BRABrazil Southeast Caucasian0.00.0000103See
BRABrazil Southeast Mixed Race0.00.000042See
CAFCentral African Republic Aka Pygmy0.00.000093See
CANCanada British Columbia Athabaskan0.000062See
CANCanada British Columbia Penutian0.000026See
CHNChina Hong Kong and Singapore0.0000135See
CHNChina Yunnan Province Lahu0.000070See
CODCongo Kinshasa Bantu0.00.000090See
COLColombia Bogota and Medellin Mestizo0.000065See
CZECzech Republic0.0000106See
PRYParaguay Lengua0.000017See
PHLPhilippines Ivatan0.00.000050See
RUSRussia Siberia Chukchi0.000071See
RUSRussia Siberia Negidal0.000035See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
RUSRussia Siberia Gvaysugi Udege0.000025See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.000032See
RUSRussia Siberia Chukotka Peninsula Chukchi0.000059See
RUSRussia Siberia Chukotka Peninsula Eskimo0.000080See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
MNGMongolia Tsaatan0.0000144See
MARMorocco Nador Metalsa0.000099See
MARMorocco Settat Chaouya0.000098See
MEXMexico Highlands Mestizos0.00.0000160See
MEXMexico Nuevo Leon Mestizo0.00.000040See
MKDMacedonia pop 10.0000158See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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