Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.

Allele: 
   

DRB1*12

 
Allele reported 384 time(s) and present in 340 population(s).

Population Phenotype
Frequency (%)
Allele
Frequency
(in_decimals)
Sample
Size
IMGT/HLA¹
Database
Distribution² Haplotype³
Association
Notesª
MMRMyanmar Kachin66.70.436563See
MMRMyanmar Chin63.60.418255See
MMRMyanmar Kayin56.80.386444See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.355094See
MYSMalaysia pop 20.299062See
MMRMyanmar Bamar45.70.271747See
VNMVietnam Hanoi0.270050See
MYSMalaysia pop 30.27001445See
MMRMyanmar Shan42.60.240754See
MMRMyanmar Rakhine39.60.239648See
MYSMalaysia Perak Rawa0.220023See
MMRMyanmar Mon31.30.179764See
MMRMyanmar Kayah30.90.172755See
THAThailand pop 40.169016807See
THAThailand pop 20.1690124See
RUSRussia Nenet Mixed0.164055See
CHNChina Beijing and Guangzhou0.15401592See
MYSMalaysia Negeri Sembilan Minangkabau0.150034See
CHNChina Shanghai0.141026266See
TWNTaiwan Minnan pop 20.14107137See
TWNTaiwan Chinese immigrants from Middle China0.1290211See
TWNTaiwan Hakka pop 20.1290714See
TWNTaiwan Chinese immigrants from North China0.1280152See
TWNTaiwan Chinese immigrants from South China0.1270172See
CHNChina Jiangsu Province0.122020248See
CHNChina Guangdong Province22.80.1213403See
USAUSA OPTN Asian0.1130261See
BGDBangladesh Dhaka Bangalee0.1130141See
CHNChina Shaanxi Province Han0.111010000See
CHNChina Shandong Province Linqu County20.90.1106139See
CHNChina Shandong Province19.50.10307418See
CHNChina Han18.20.0955314See
TWNTaiwan Aborigine0.0860111See
RUSRussia South Ural Bashkir16.40.0820146See
KORSouth Korea pop 80.08007096See
INDIndia New Delhi pop 20.0740102See
INDIndia Tamil Nadu Dravidian0.0710156See
GABGabon Haut-Ogooue Dienga0.0660167See
JPNJapan pop 100.0570332See
USAUSA Southeast African American9.80.0540112See
USAUSA OPTN African American0.04701510See
NGANigeria9.30.0467258See
INDIndia Tamil Nadu Chennai8.80.0450137See
BRABrazil Parana Oriental9.10.045033See
ARGArgentina Chubut Tehuelche0.043023See
MEXMexico Campeche Rural0.042647See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks8.00.0400112See
BLRBelarus Vitebsk Region0.040070See
RUSRussia Northwest pop 38.00.0400100See
MOZMozambique0.0400202See
INDIndia North Gujarat7.20.0390338See
ITAItaly pop 20.038053See
BLRBelarus Brest Region0.0380105See
TZATanzania Dodoma Kongwa0.0380212See
RUSRussia Murmansk Saomi Mixed0.037070See
MEXMexico Colima Rural0.034143See
MEXMexico Veracruz, Poza Rica0.033345See
ARMArmenia Shirak0.033076See
TURTurkey Istanbul6.40.0325250See
BRABrazil Parana Mulatto6.40.0320186See
BRABrazil Parana Afro Brazilian6.50.032077See
ALBAlbania0.0310160See
ITAItaly North Pavia0.031081See
INDIndia Andhra Pradesh Sunni1.50.0300100See
LKASri Lanka Colombo Sinhalese0.0300101See
MEXMexico Campeche, Campeche city0.029434See
MEXMexico Mexico City Center0.0292152See
MEXMexico Jalisco, Tonala0.028635See
SVKSlovakia pop 20.02744234See
BRABrazil South Ribeirao Preto0.0270184See
INDIndia North pop 30.0264587See
BIHBosnia and Herzegovina0.0261134See
RUSRussia Moscow0.02602650See
GBRUnited Kingdom North0.0260330See
ALBAlbanian Kosovo0.0250120See
HRVCroatia pop 20.0250100See
VENVenezuela Zulia Maracaibo Mixed0.025020See
RUSRussia Arkhangelsk0.025081See
CZECzech Republic pop 35.00.0250180See
MEXMexico Hidalgo Rural0.024781See
MEXMexico Colima, Colima city0.024661See
ITAItaly pop 64.90.0245184See
RUSRussia Moscow Pop 24.70.02352000See
POLPoland pop 34.60.02302907See
JAMJamaica0.0230132See
ITAItaly Sardinia0.023086See
RUSRussia Smolensk0.0230156See
UKRUkraine Khmelnytskyi0.0220138See
BRABrazil Minas Gerais State Mixed4.30.02201000See
ISRIsrael Jews pop 24.50.022023000See
GBRUnited Kingdom East0.0220163See
RUSRussia South Ural Tatar4.40.0220135See
GBRUnited Kingdom renal patients4.30.02207007See
ARMArmenia living in Lebanon0.0220368See
NORNorway ethnic Norwegians4.30.02194510See
BRABrazil REDOME Sergipe0.02117321See
AUSAustralia West Caucasian4.20.0210891See
MEXMexico Mexico City Mestizo0.0210121See
SRBSerbia Vojvodina4.20.0210400See
SRBSerbia0.0210386See
PRTPortugal South pop 20.02101021See
INDIndia Bikaner Non-Raikas4.20.0210127See
MEXMexico Jalisco, Zapopan0.0208168See
CZECzech Republic Kurd4.10.020374See
BRABrazil Southeast Campinas Mixed4.00.020299See
SWESweden pop 44.00.0202966See
SWESweden pop 50.02001569See
RUSRussia Northwest4.10.02001011See
PRTAzores Terceira Island0.0200130See
TTOTrinidad African0.020067See
ROMRomania pop 20.02006936See
RUSRussia Northwest pop 24.00.0200346See
RUSRussia Kostroma Region0.0200126See
RUSRussia Samara Region0.02002500See
MEXMexico Baja California Rural0.020050See
MEXMexico Michoacan, Morelia0.0199150See
MKDMacedonia MBMDR - Macedonian Muslims3.90.019776See
ALBAlbania pop 23.90.0197432See
MKDMacedonia MBMDR - Albanian3.90.0195128See
FRAFrance Marseille3.90.01931000See
BRABrazil REDOME Rio de Janeiro0.0192139322See
MEXMexico Mexico City South0.019252See
SRBSerbia pop 33.80.01911992See
MEXMexico Guadalajara Mestizo0.019054See
RUSRussia Arkhangelsk Pomor0.019063See
SWESweden Stockholm2.20.01901347See
PRTPortugal Aveiro0.01905933See
MEXMexico Chiapas, Tuxtla Gutierrez0.018952See
BRABrazil REDOME Alagoas0.018825349See
CHESwitzerland Basel0.01881888See
GBRUnited Kingdom South West0.0187163See
BRABrazil REDOME Acre0.0186859See
DEUGermany3.70.018611407See
GBRUnited Kingdom Orkney0.018488See
BRABrazil Curitiba-Parana Mixed0.0181264See
BRABrazil Piaui Mixed0.018021943See
IRLIreland Donegal3.50.0180200See
PRTPortugal Coimbra0.01805057See
BRABrazil South East Cord Bllod0.018011409See
CHESwitzerland Aargau-Solothurn0.01801838See
BRABrazil Rio Grande do Sul Black0.0180248See
BRABrazil Rio Grande do Sul Caucasoid0.01804428See
BRABrazil REDOME Minas Gerais0.0177211275See
CHESwitzerland Graubunden0.0177759See
ENGEngland Lancaster3.50.0176545See
MKDMacedonia MBMDR - Macedonian3.50.01751283See
BRABrazil REDOME Piaui0.017446140See
BRABrazil REDOME Bahia0.017247399See
GHAGhana Accre Asutuare Akan0.0170429See
ITAItaly Central0.0170380See
BRABrazil Sao Paulo Bauru Mixed0.01703542See
FINFinland0.017091See
WALWales pop 23.40.017039979See
PRTPortugal Setubal0.01705268See
BRABrazil Parana Caucasian3.50.01702775See
BRABrazil REDOME Espirito Santo0.016988485See
BRABrazil REDOME Pernambuco0.016892332See
BRABrazil REDOME Goias0.016888574See
MEXMexico Chihuahua Chihuahua City0.0168119See
MEXMexico Jalisco, Tlajomulco0.016730See
BRABrazil REDOME Sao Paulo0.0167800809See
BRABrazil REDOME Roraima0.01664140See
ITAItaly South Campania Region3.30.01661089See
MEXMexico Mexico City Metropolitan Area Rural0.0164150See
BRABrazil REDOME Rio Grande do Sul0.0163241329See
BRABrazil REDOME Federal District0.016229549See
BRABrazil REDOME Mato Grosso0.016134649See
ENGEngland Sheffield3.20.01614755See
BRABrazil Parana Cafuzo3.10.0160319See
PRTPortugal Portalegre0.01601254See
GRCGreece pop 50.0160500See
FRAFrance Southeast3.10.0160130See
USAUSA OPTN Caucasian0.01608525See
BRABrazil REDOME Santa Catarina0.0159106673See
BRABrazil REDOME Parana0.0159341639See
CHESwitzerland Bern0.01593545See
MEXMexico Aguascalientes state0.015895See
BRABrazil REDOME Mato Grosso do Sul0.015795667See
CHESwitzerland Zurich0.01564875See
CHESwitzerland Lausanne0.0156993See
BRABrazil REDOME Paraiba0.015643868See
MEXMexico Nayarit Rural0.015664See
MEXMexico Nayarit, Tepic0.015597See
BRABrazil REDOME Tocantins0.015420692See
BRABrazil REDOME Rondonia0.015354396See
BRABrazil REDOME Ceara0.0152101217See
ESPSpain North3.00.0151156See
ENGEngland Manchester3.00.01511640See
POLPoland Lodz0.0150103See
PRTPortugal Lisbon0.015017420See
PRTPortugal Viseu0.01502915See
PRTAzores0.01501050See
PRTPortugal Evora0.0150737See
PRTPortugal Bragança0.0150301See
ARMArmenia living in USA0.0150233See
ARMArmenia Lori0.0150102See
INDIndia Andhra Pradesh Brahmin0.80.015098See
WALWales3.10.01501798See
PAKPakistan Mixed Sindhi0.0150101See
SVKSlovakia0.0150146See
ITAItaly North pop 22.90.01502054See
BRABrazil North East Mixed0.0150205See
GRCGreece pop 70.014911250See
CHESwitzerland Geneva pop 20.01471267See
MEXMexico Mexico City West0.014733See
CHESwitzerland Lugano0.01461169See
FRAFrance South2.90.0146350See
ENGEngland Leeds2.90.01465024See
CHESwitzerland Luzern0.01451553See
BRABrazil REDOME Rio Grande do Norte0.014446603See
ARMArmenia Yerevan0.0140445See
GRCGreece North0.0140500See
FRAFrance Grenoble2.80.01401000See
BRABrazil Rio Grande do Norte Mestizo0.014012973See
PRTPortugal Leiria0.01401847See
PRTPortugal Porto0.01407937See
MKDMacedonia0.0140286See
MEXMexico Guerrero state0.0139144See
MEXMexico Chihuahua, Ciudad Juarez0.0139106See
CHESwitzerland Sion0.0138832See
BRABrazil REDOME Maranhao0.013810180See
MEXMexico Coahuila, Saltillo0.013772See
CHESwitzerland St Gallen0.01362113See
SDNSudan Central Shaigiya Mixed2.70.013536See
ROMRomania pop 32.70.01341469See
MEXMexico Nuevo Leon, Monterrey city0.0133226See
BRABrazil REDOME Para0.013272637See
ITAItaly North Pavia pop 30.0132685See
USAUSA OPTN Hispanic0.01301580See
PRTPortugal Center pop 20.0130562See
BRABrazil Rio Grande do Sul Mixed0.0130324See
ARMArmenia Syunik0.0130117See
PRTPortugal Santarem0.01303865See
ARGArgentina Corrientes2.60.0130155See
ZAFSouth Africa Limpopo Venda0.0130117See
ITAItaly Lombardy2.50.0130674See
MEXMexico Jalisco, Tlaquepaque0.012839See
ECUEcuador Coast Mixed Ancestry0.0126238See
ENGEngland Liverpool2.50.01251343See
BRABrazil REDOME Amapa0.012417864See
BRABrazil REDOME Amazonas0.012224129See
FRAFrance Bordeaux2.40.0122990See
MEXMexico Tabasco, Villahermosa0.012282See
ENGEngland Newcastle2.40.01202739See
PRTPortugal Guarda0.0120797See
AREUnited Arab Emirates pop 22.40.0120373See
RUSRussia Vologda0.0120121See
ITAItaly North Pavia pop 22.50.01202416See
RUSRussia Mari0.0120202See
BRABrazil Mato Grosso do Sul0.0120203See
FRAFrance Grenoble, Nantes and Rennes0.01206094See
ENGEngland North West Mixed pop 22.40.0119379See
RUSRussia North Ossetian2.40.0118127See
FRAFrance Lyon2.30.01164813See
MEXMexico Coahuila Rural0.0115216See
MEXMexico Coahuila, Torreon0.0113396See
GBRUnited Kingdom Central0.0113135See
PRTPortugal Braga0.01101971See
PERPeru Quechua0.011044See
CZECzech Republic Gypsy pop 22.20.010946See
PRTPortugal Faro0.01001242See
PRTPortugal Beja0.0100699See
UKRUkraine Lvov0.0100102See
ESPSpain Northwest2.00.01001818See
RUSRussia South Ural Russian1.90.0100207See
ARGArgentina Buenos Aires pop 21.70.01001216See
BFABurkina Faso Fulani0.010049See
BFABurkina Faso Mossi0.010053See
ENGEngland2.00.0100537See
IRLIreland Wexford2.00.0100200See
TURTurkey Ankara0.010050See
TTOTrinidad South Asian0.010087See
MEXMexico Baja Californa, Mexicali0.0100100See
MEXMexico Quintana Roo Rural0.010050See
IRNIran pop 40.0098855See
RUSRussia Tatars0.0098355See
ESPSpain Valencia1.90.0095577See
FRAFrance Rennes pop 41.90.00941000See
IRQIraq Erbil1.90.0094372See
MEXMexico Mestizo pop 40.0093269See
MEXMexico Durango Rural0.0092326See
MEXMexico Guanajuato Rural0.0092162See
JORJordan0.009015141See
IRNIran0.009058See
ESPSpain Majorca0.0090407See
ARMArmenia living in Karabakh0.0090445See
IRLIreland South pop 20.008917624See
MEXMexico Veracruz, Coatzacoalcos0.008955See
PRTPortugal North pop 20.00881801See
HRVCroatia pop 31.70.0083120See
BIHBosnia and Herzegovina pop 21.70.0083120See
MEXMexico Veracruz, Orizaba0.008360See
MEXMexico Chiapas Rural0.0083121See
PRTPortugal Castelo Branco0.0080327See
PRTPortugal Viana do Castelo0.0080706See
HRVCroatia Gorski Kotar Region0.008063See
IRNIran Royan Cord Blood Bank1.70.008015600See
ARMArmenia Ghegharkunik0.0080242See
ARGArgentina La Plata2.00.0080100See
ESPSpain Ibiza0.008088See
MEXMexico Yucatan, Merida0.0077192See
MEXMexico Jalisco, Guadalajara city0.00711189See
MEXMexico Tabasco Rural0.0070142See
PRTPortugal Vila Real0.00701167See
PRTMadeira pop 30.0070538See
BLRBelarus Gomel Region0.0070100See
MEXMexico Nuevo Leon Rural0.0068439See
MEXMexico Mexico City North0.0066751See
MEXMexico Veracruz Rural0.0065539See
MEXMexico Guanajuato, Leon0.006478See
ECUEcuador Mixed Ancestry0.00641173See
MEXMexico Mexico City East0.006379See
MEXMexico Oaxaca Rural0.0062485See
ESPSpain Majorcans Jews0.0060103See
BRABrazil Sao Paulo Mixed1.30.0060239See
ARMArmenia living in Iran0.006085See
PAKPakistan Mixed Pathan0.0050100See
MARMorocco pop 20.0050110See
MEXMexico Sinaloa, Culiacán0.0049103See
ECUEcuador Andes Mixed Ancestry0.0049824See
MEXMexico Zacatecas, Fresnillo0.0048103See
MEXMexico Tlaxcala Rural0.0048830See
MEXMexico Jalisco Rural0.0043585See
MEXMexico Michoacan Rural0.0043348See
MEXMexico Puebla, Puebla city0.00431994See
MEXMexico Chihuahua Rural0.0042236See
INDIndia Bikaner Raikas0.70.0040143See
MEXMexico Tamaulipas Rural0.0040125See
ARGArgentina Cuyo Region0.70.0040420See
ITAItaly Sardinia pop20.80.00401129See
SAUSaudi Arabia pop 20.0040383See
TURTurkey pop 20.0040228See
MEXMexico Zacatecas Rural0.0037266See
MEXMexico Yucatan Rural0.0037132See
MEXMexico Puebla Rural0.0030833See
MEXMexico Tlaxcala, Tlaxcala city0.0028181See
MEXMexico Veracruz, Xalapa0.0027187See
MEXMexico Sinaloa Rural0.0027183See
MEXMexico Sonora Rural0.0025197See
SAUSaudi Arabia pop 40.20.0010499See
GRCGreece0.00.000048See
BRABrazil East Amazon0.000041See
PRYParaguay Aché0.000087See
GBRUnited Kingdom pop 20.0000101See
PAKPakistan Kalash0.000069See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
BRABrazil Guarani M bya0.000093See
BRABrazil Kaingang0.0000235See
FRAFrance West0.00.0000100See
MEXMexico Huasteca Region Teenek0.000055See
ARGArgentina Salta Wichi pop 20.00.000019See
ESPSpain Minorca0.000094See
BFABurkina Faso Rimaibe0.000047See
ESPSpain Gipuzkoa Basque0.0000100See
ESPSpain Catalonia Girona0.000088See
MEXMexico Puebla Mestizo0.000099See
MEXMexico Sinaloa Mestizo0.000056See
ARGArgentina Rio Negro Mapuche0.000034See
FRAFrance West Breton0.0000150See
ARGArgentina Kolla0.000061See
CHLChile Huilliche0.000040See
PAKPakistan Karachi Parsi0.000091See
ECUEcuador Amazonia Mixed Ancestry0.000039See
MEXMexico Veracruz, Veracruz city0.0000171See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Morelos, Cuernavaca0.000082See
MEXMexico Oaxaca, Oaxaca city0.0000151See
MEXMexico Veracruz, Cordoba0.000056See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Sonora, Hermosillo0.000099See
MEXMexico Sonora, Ciudad Obregón0.0000143See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Durango, Durango city0.0000153See
MEXMexico Queretaro Rural0.000043See
MEXMexico San Luis Potosi Rural0.000087See
MEXMexico Morelos Rural0.000030See
MEXMexico Baja California, Tijuana0.000025See

Frequency data at lower resolution for this allele can be found in links below


Allele  Number of Populations 

Notes:

* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


   

Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

support@allelefrequencies.net


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