Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 138 time(s) and present in 104 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
USAUSA Arizona Gila River Amerindian0.1280492See
MYSMalaysia Mandailing14.80.111027See
MYSMalaysia Pahang Semai7.90.039038See
IDNIndonesia Java Western6.80.0350236See
MYSMalaysia Peninsular Chinese5.70.0284194See
MYSMalaysia Peninsular Malay4.30.0231951See
MYSMalaysia Jelebu Temuan0.021025See
MYSMalaysia Sarawak Bau Bidayuh0.020025See
MYSMalaysia Kedah Baling Kensiu0.020025See
MYSMalaysia Patani4.00.020025See
MYSMalaysia Kelantan3.60.018028See
CHNChina Marrow Donor Registry0.0180600See
VNMVietnam Hanoi Kinh pop 20.0180170See
SGPSingapore SGVP Malay MAS0.018089See
TWNTaiwan Han Chinese0.0160504See
CHNChina Sichuan HIV negative0.015034See
MEXMexico Sonora Seri0.015034See
USAUSA NMDP Vietnamese0.013243540See
SGPSingapore Chinese2.70.0130149See
CHNChina Canton Han0.0130264See
HKGHong Kong Chinese cord blood registry0.01303892See
CHNChina Hubei Han2.50.01253732See
DEUGermany DKMS - China minority0.01251282See
USAUSA NMDP Chinese0.012299672See
TWNTaiwan Tzu Chi Morrow Donor Registry0.011946682See
INDIndia Northeast UCBB2.40.0118296See
CHNChina Jiangsu Han0.01103238See
SGPSingapore SGVP Chinese CHS0.011096See
HKGHong Kong Chinese BMDR0.01067595See
HKGHong Kong Chinese1.90.0100569See
CHNChina Yunnan Province Han0.0100101See
ARMArmenia combined Regions0.0100100See
TWNTaiwan pop 30.0100212See
USAUSA Mexican American Mestizo0.0090553See
IRNIran Yazd0.008956See
USAUSA NMDP Mexican or Chicano0.0081261235See
TWNTaiwan Tzu Chi Cord Blood Bank0.0080710See
USAUSA North American Native0.0080187See
CHNChina Southwest Dai0.0080124See
CHLChile Mapuche0.007766See
USAUSA NMDP North American Amerindian0.007635791See
MEXMexico Oaxaca Zapotec0.007090See
USAUSA NMDP Korean0.006577584See
USAUSA Asian pop 20.00621772See
KORSouth Korea pop 100.00614128See
KORSouth Korea pop 30.0060485See
MEXMexico Veracruz Xalapa1.20.006084See
SGPSingapore SGVP. Indian INS0.006086See
TWNTaiwan pop 20.0060364See
USAUSA Hispanic pop 20.00551999See
USAUSA NMDP Filipino0.005450614See
USAUSA NMDP American Indian South or Central America0.00505926See
USAUSA San Diego1.00.0050496See
CHNChina Beijing Shijiazhuang Tianjian Han0.0050618See
CHNChina Guangxi Region Maonan0.0050108See
MEXMexico Mexico City Mestizo pop 20.0043234See
JPNJapan pop 50.0040117See
USAUSA Hispanic0.0040234See
USAUSA NMDP Alaska Native or Aleut0.00401376See
USAUSA Asian0.0040358See
MEXMexico Mexico City Mestizo population0.0035143See
CHNChina Jiangsu Province Han0.0035334See
USAUSA NMDP Southeast Asian0.003327978See
NICNicaragua Managua0.60.0030339See
ZAFSouth Africa Worcester1.00.0030159See
AREUnited Arab Emirates Pop 10.0030570See
JPNJapan pop 30.00301018See
SAUSaudi Arabia pop 6 (G)0.002928927See
USAUSA NMDP Japanese0.002624582See
USAUSA NMDP Hispanic South or Central American0.0024146714See
JPNJapan pop 160.002418604See
CHESwitzerland Zurich0.00234875See
USAUSA African American0.0020252See
USAUSA Caucasian pop 40.00191070See
MYSMalaysia Peninsular Indian0.40.0018271See
USAUSA NMDP Hawaiian or other Pacific Islander0.001511499See
USAUSA NMDP Caribean Hispanic0.0010115374See
USAUSA African American pop 80.0010605See
JPNJapan Central0.0010371See
LKASri Lanka Colombo0.30.0010714See
USAUSA NMDP African American pop 20.0008416581See
DEUGermany DKMS - France minority0.00071406See
USAUSA NMDP African0.000628557See
ISRIsrael YemenJews0.000615542See
DEUGermany DKMS - Romania minority0.00051234See
USAUSA NMDP Caribean Black0.000533328See
INDIndia Tamil Nadu0.00042492See
USAUSA African American pop 40.00042411See
DEUGermany DKMS - Turkey minority0.00034856See
DEUGermany DKMS - Netherlands minority0.00041374See
INDIndia East UCBB0.00.00022403See
DEUGermany DKMS - Greece minority0.00031894See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000270890See
USAUSA NMDP South Asian Indian0.0002185391See
INDIndia West UCBB0.00.00015829See
USAUSA NMDP European Caucasian0.00011242890See
ISRIsrael Iran Jews0.00018153See
INDIndia South UCBB0.00.000011446See
DEUGermany DKMS - German donors0.00003456066See
ISRIsrael Morocco Jews0.000036718See
ISRIsrael Ethiopia Jews0.00005928See
ITAItaly North pop 30.00.000097See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
MEXMexico Oaxaca Mixtec0.0000103See
DEUGermany pop 80.000039689See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CHNChina North Han0.0000105See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian pop 20.0000265See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA European American pop 20.00001245See
ZAFSouth Africa Natal Zulu0.00.0000100See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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