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Home	Populations	HLA	KIR	Other polymorphisms	HLA-ADR	KDDB

HLA-ADR » Adverse drug reaction association studies search

Please specify your search by selecting options from boxes. Then, click "Search" to find different HLA adverse drug reaction association studies that match your criteria. Remember at least one option must be selected.

Choose from only one option on this row:	Gene:  All genes All MHC Class I All MHC Class II All HLA-A All HLA-B All HLA-C All HLA-DPB All HLA-DPB1 All HLA-DQA1 All HLA-DQB All HLA-DQB1 All HLA-DRB1 All HLA-DRB3 All HLA-DRB4 All HLA-DRB5    OR    allele:  All alleles A*01 A*01:01 A*01:02 A*01:03 A*02 A*02:01 A*02:02 A*02:03 A*02:05 A*02:06 A*02:07 A*02:08 A*02:10 A*02:11 A*02:12 A*02:81 A*03 A*03:01 A*03:02 A*11 A*11:01 A*11:10 A*11:53 A*2 A*21:02 A*23:01 A*24 A*24:01 A*24:02 A*24:03 A*24:05 A*24:07 A*24:10 A*24:13 A*24:20 A*25:01 A*26:01 A*26:02 A*26:03 A*26:05 A*26:08 A*26:09 A*29:01 A*29:02 A*30:01 A*30:02 A*30:04 A*31:01 A*32:01 A*32:04 A*33 A*33:01 A*33:03 A*34:02 A*36:01 A*36:02 A*43:01 A*66:01 A*68:01 A*68:02 A*68:03 A*69:01 A*74:01 A*80:01 A*92:19 B*07 B*07:02 B*07:05 B*07:11 B*08:01 B*13:01 B*13:02 B*13:10 B*13:15 B*14.01 B*14.02 B*14:01 B*14:02 B*15:01 B*15:02 B*15:03 B*15:05 B*15:07 B*15:10 B*15:11 B*15:12 B*15:13 B*15:15 B*15:17 B*15:18 B*15:19 B*15:21 B*15:24 B*15:25 B*15:27 B*15:35 B*15:39 B*15:42 B*15:58 B*18:01 B*18:02 B*18:04 B*27:02 B*27:04 B*27:05 B*27:06 B*27:07 B*27:09 B*35:01 B*35:02 B*35:03 B*35:05 B*35:08 B*35:10 B*35:31 B*35:34 B*37:01 B*37:10 B*38:01 B*38:02 B*39:01 B*39:02 B*39:03 B*39:04 B*39:05 B*39:06 B*39:09 B*39:24 B*40:01 B*40:02 B*40:06 B*41:01 B*42:01 B*44 B*44:02 B*44:03 B*44:08 B*44:26 B*45:01 B*46:01 B*46:02 B*47:01 B*48:01 B*48:04 B*49:01 B*50:01 B*50:02 B*51:01 B*51:02 B*51:06 B*51:07 B*51:08 B*52:01 B*53:01 B*54:01 B*54:17 B*55:01 B*55:02 B*56:01 B*56:02 B*56:04 B*56:10 B*57 B*57:01 B*57:03 B*57:11 B*58:01 B*58:02 B*58:03 B*58:04 B*58:05 B*59:01 B*67:01 B*73:01 B*78:01 B*78:06 B*81:01 C*01:02 C*02:02 C*02:10 C*03:02 C*03:03 C*03:04 C*04:01 C*04:03 C*05:01 C*06:02 C*07 C*07:01 C*07:02 C*07:04 C*07:18 C*08:01 C*08:02 C*12 C*12:02 C*12:03 C*14:02 C*14:03 C*15:02 C*15:05 C*16 C*16:01 C*17:01 DPB*02:01 DPB*03:01 DPB*04:01 DPB*04:02 DPB1*02:01 DPB1*02:02 DPB1*03:01 DPB1*04:01 DPB1*04:02 DPB1*05:01 DPB1*09:01 DPB1*13:01 DPB1*14:01 DPB1*17:01 DQA1*01:01 DQA1*01:02 DQA1*01:03 DQA1*02:01 DQA1*03:01 DQA1*03:03 DQA1*04:01 DQA1*05:01 DQB*02:01 DQB*05:02 DQB*05:03 DQB*06:03 DQB*06:04 DQB1*02:01 DQB1*02:02 DQB1*03 DQB1*03:01 DQB1*03:02 DQB1*03:03 DQB1*04:01 DQB1*04:02 DQB1*05:01 DQB1*05:02 DQB1*05:03 DQB1*06:01 DQB1*06:02 DQB1*06:03 DQB1*06:04 DQB1*06:09 DQB1*06:20 DQB1*30:20 DQB1*50:10 DQB1*60:20 DRB1*01 DRB1*01:01 DRB1*01:02 DRB1*01:03 DRB1*012:02 DRB1*03 DRB1*03:01 DRB1*03:15 DRB1*03:17 DRB1*04 DRB1*04:01 DRB1*04:02 DRB1*04:03 DRB1*04:04 DRB1*04:05 DRB1*04:06 DRB1*04:07 DRB1*04:08 DRB1*04:10 DRB1*07:01 DRB1*08 DRB1*08:01 DRB1*08:02 DRB1*08:03 DRB1*08:06 DRB1*09 DRB1*09:01 DRB1*10 DRB1*10:01 DRB1*10:10 DRB1*11 DRB1*11:01 DRB1*11:02 DRB1*11:03 DRB1*11:04 DRB1*11:12 DRB1*12 DRB1*12:01 DRB1*12:02 DRB1*13 DRB1*13:01 DRB1*13:02 DRB1*13:03 DRB1*13:05 DRB1*13:12 DRB1*14 DRB1*14:01 DRB1*14:03 DRB1*14:05 DRB1*14:06 DRB1*14:09 DRB1*14:17 DRB1*14:43 DRB1*14:54 DRB1*15 DRB1*15:01 DRB1*15:02 DRB1*16 DRB1*16:01 DRB1*16:02 DRB1*40:30 DRB1*40:50 DRB3*01:01 DRB3*02:02 DRB4*01:01 DRB5*01:01 DRB5*02    OR    Non-standard (e.g. serotype) :  Omit All non-standard A1 A11 A2 A24 A26 A3 A30 A31 A33 B13 B14 B27 B35 B37 B38 B39 B44 B46 B48 B51 B52 B54 B55 B56 B58 B59 B60 B61 B62 B67 B7 B71 B75 C8 DQA1 DQA2 DQA3 DQA5 DQB2 DQB5 DQB6 DQB7 DQB8 DR1 DR11 DR12 DR13 DR14 DR15 DR16 DR4 DR7 DR8 DR9 DRB4
Additional Parameters:	Drug:  All drugs abacavir allopurinol amoxicillin-clavulanate antibacterial drugs antiepileptic drugs antituberculosis drugs asparaginase aspirin benznidazole bucillamine carbamazepine clarithromycin clindamycin clozapine co-trimoxazole dapsone EGF receptor inhibitors enalapril erythromycin fenofibrate flucloxacillin flupirtine lamotrigine lapatinib levetiracetam lumiracoxib methazolamide methyldopa minocycline nevirapine NSAID and 'multi-ingredient cold medication' oxcarbazepine oxicam NSAIDs paracetamol phenobarbital phenytoin sertraline statins sulfamethoxazole sulfasalazine terbinafine tetanus antitoxin ticlopidine trastuzumab trichloroethylene valproic acid vancomycin ximelagatran     Patient ethnicity:  All Arab Black Caucasian Diverse European Han Chinese Indian Japanese Korean Malay Thai Vietnamese     p-value filter:  All p-values < 0.05 < 0.01 < 0.001     Patient disease:  All diseases bacterial infections blood clot blood pressure breast cancer cancer chagas disease cholesterol common cold depression epilepsy fungal infections gout HIV inflammation leprosy osteoarthritis pain rheumatoid arthritis schizophrenia tetanus tuberculosis     ADR:  All drug-induced hypersensitivity syndrome (DIHS) toxic epidermal necrolysis (TEN) aspirin-induced urticaria (AIU) maculopapular eruption (MPE) elevated levels of serum alanine aminotransferase (ALAT) jaundice severe occular complicatoins drug-induced skin reaction (DISI) fixed drug eruption aspirin-intolerant asthma (AIA) bucillamine-induced proteinuria agranulocytosis acute generalized exanthematous pustulosis (AGEP) Stevens-Johnson syndrome (SJS) Stevens–Johnson syndrome (SJS) Autoimmune-mediated necrotizing myositis severe ocular surface complications drug induced liver injury (DILI) anti-HMGCR-myopathy maculopapular exanthema (MPE)     Country:  All countries Australia Brazil Canada China England France Germany Hong Kong Hungary India Indonesia Iran Italy Japan Malawi Malaysia Portugal Scotland Singapore South Africa South Korea Spain Sweden Switzerland Taiwan Thailand Tunisia United Kingdom United States Vietnam Worldwide     Geographic region:  All regions Africa Asia Europe North America Oceania South America
Sort by:	Study Drug Name Allele

Legend
¹ Pat → Patients
² ExpCtrl → Drug Exposed Controls
³ Pop → General Population Controls

Line	PubMed Link	Drug	Allele	Old Allele Name	Cohort ethnicity	p-value Pat1 and ExpCtrl2	p-value Pat1 and Pop3	Pat1 allele or carrier frequency	ExpCtrl2 allele or carrier frequency	Pop3 allele or carrier frequency	More Details	Allele distribution

Please cite this website using the following reference:
Ghattaoraya GS, Dundar Y, González-Galarza FF, Maia MH, Santos EJ, da Silva AL, McCabe A, Middleton D, Alfirevic A, Dickson R and Jones AR
A web resource for mining HLA associations with adverse drug reactions: HLA-ADR
Database (Oxford) 2016. View full article