The Allele Frequency Net Database [KIR Database Breakdowns]

KIR Database » Breakdowns

Summary

To summarise KIR data stored in the Allele Frequency Net Database we have classified alleles grouped by Gene. Most frequently are listed on the right side.

KIR Alleles

Gene	Alleles (IPD-KIR)	Alleles Reported in Website	Total Entries
KIR-2DL1	43	21	220
KIR-2DL2	27	4	203
KIR-2DL3	32	7	213
KIR-2DL4	47	11	250
KIR-2DL5	0	0	124
KIR-2DL5A	15	5	31
KIR-2DL5B	25	18	45
KIR-2DP1	22	0	96
KIR-2DS1	15	3	183
KIR-2DS2	22	4	175
KIR-2DS3	13	7	154
KIR-2DS4	30	10	205
KIR-2DS5	16	8	159
KIR-3DL1	70	41	761
KIR-3DL2	84	11	276
KIR-3DL3	101	39	175
KIR-3DP1	23	1	96
KIR-3DS1	16	8	243
Total	601	198	3,609

Table 3.1 KIR alleles reported in allelefrequencies.net

% HLA Alleles reported in website

% Total Entries in Website

Top KIR Allele Entries

Allele or Gene	Total Entries
KIR-3DS1	173
KIR-2DL3	170
KIR-2DL2	170
KIR-2DS1	170
KIR-2DS2	170
KIR-3DL1	169
KIR-2DL1	168
KIR-2DS3	142
KIR-2DS4	138
KIR-2DS5	138
KIR-3DL2	136
KIR-2DL4	133
KIR-2DL5	124
KIR-3DL3	122
KIR-2DP1	96
KIR-3DP1	88
KIR-3DL1*01502	52
KIR-3DL1*007	52
KIR-3DL1*008	52
KIR-3DL1*002	52
KIR-3DL1*005	51
KIR-3DL1*009	51
KIR-3DL1*006	49
KIR-3DL1*019	48
KIR-3DS1*014	46
KIR-3DL1*020	43
KIR-3DS1*01301	41
KIR-3DL1*01501	40
KIR-3DS1*049N	40
KIR-3DL1*018	39
KIR-3DL1*017	39

Table 3.2 KIR alleles with most times reported in allelefrequencies.net

KIR organisation

The figures shown below present a summary of relationships between KIR genes organised by telomeric and centromeric content. The aim of these figure is to describe the strongest relationships among the different KIR genes. Values are shown in percentages. The presence of the genes are taken from the genotype list which is available on the website.

For instance in the first figure, 3DL3 was found to be present 59% of the times that 2DS2 was also present. On the other hand, only 1% of the times both were absent as shown in the second figure.

Positives


	Centromeric							Telomeric
	3DL3	2DS2	2DL2	2DL3	2DS3	2DP1	2DL1	3DP1	2DL4	3DS1	3DL1	2DL5	2DS5	2DS1	2DS4	3DL2
	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
3DL3		48	49	90	29	96	96	98	100	40	93	52	34	41	93	100
2DS2			47	39	25	45	45	47	49	22	44	35	20	24	44	49
2DL2				39	25	46	45	48	49	22	45	35	20	24	44	49
2DL3					22	89	90	89	90	35	85	45	30	36	84	90
2DS3						28	28	28	29	17	26	27	9	17	25	29
2DP1							95	96	96	38	90	50	33	39	90	96
2DL1								95	96	38	90	51	33	39	90	96
3DP1									98	39	92	52	34	40	92	98
2DL4										40	93	52	35	41	93	100
3DS1											34	37	30	37	34	40
3DL1												47	29	35	92	93
2DL5													33	39	46	53
2DS5														32	29	35
2DS1															35	41
2DS4																93
3DL2

Negatives


	Centromeric							Telomeric
	3DL3	2DS2	2DL2	2DL3	2DS3	2DP1	2DL1	3DP1	2DL4	3DS1	3DL1	2DL5	2DS5	2DS1	2DS4	3DL2
	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
3DL3		0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
2DS2			50	0	47	0	0	0	0	34	2	33	36	34	3	0
2DL2				0	47	0	0	0	0	33	2	33	36	34	3	0
2DL3					3	2	3	0	0	5	1	1	5	5	1	0
2DS3						2	3	0	0	48	3	45	46	46	4	0
2DP1							2	0	0	1	0	1	1	1	0	0
2DL1								0	0	2	1	1	2	2	1	0
3DP1									0	0	0	0	0	0	0	0
2DL4										0	0	0	0	0	0	0
3DS1											0	44	55	55	1	0
3DL1												0	1	0	6	0
2DL5													45	44	0	0
2DS5														56	2	0
2DS1															1	0
2DS4																0
3DL2

©2012 Allele Frequencies Website.

Allele frequency net: a database and online repository for immune gene frequencies in worldwide populations.
Gonzalez-Galarza FF, Christmas S, Middleton D and Jones AR Nucleic Acid Research 2011, 39, D913-D919.
Liverpool, U.K.

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