To summarise HLA data stored in the Allele Frequency Net Database we have classified alleles grouped by
Locus. Most frequently alleles are listed on the right side.
HLA Alleles
Locus
Alleles (IMGT/HLA)
HLA-A
3,094
HLA-B
3,866
HLA-C
2,618
HLA-DMA
7
HLA-DMB
13
HLA-DOA
12
HLA-DOB
13
HLA-DPA1
39
HLA-DPB1
522
HLA-DQA1
54
HLA-DQB1
777
HLA-DRA
7
HLA-DRB1
1,719
HLA-DRB2
1
HLA-DRB3
59
HLA-DRB4
15
HLA-DRB5
21
HLA-DRB6
3
HLA-DRB7
2
HLA-DRB8
1
HLA-DRB9
1
HLA-E
17
HLA-F
22
HLA-G
50
HLA-H
12
HLA-J
9
HLA-K
6
HLA-L
5
HLA-P
5
HLA-V
3
HLA-Y
3
Total
12,976
Top HLA Allele Entries
Allele
Total Entries
HLA-DRB1*03:01
534
HLA-DQB1*03:01
530
HLA-DQB1*03:02
526
HLA-DRB1*01:01
489
HLA-DRB1*13:01
484
HLA-DRB1*15:01
483
HLA-DRB1*04:03
478
HLA-DRB1*11:01
473
HLA-DRB1*04:04
473
HLA-DRB1*10:01
470
HLA-DRB1*07:01
469
HLA-DRB1*13:02
460
HLA-DRB1*14:01
458
HLA-B*35
452
HLA-B*51
449
HLA-B*07
445
HLA-DRB1*12:01
444
HLA-A*24
442
HLA-B*44
442
HLA-A*02
440
HLA-DRB1*04:05
433
HLA-A*33
433
HLA-A*03
433
HLA-DRB1*07
431
HLA-B*39
431
HLA-DRB1*04:01
430
HLA-B*27
428
HLA-B*13
426
HLA-A*11
426
HLA-DQB1*03:03
424
Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.