Allele Frequencies in World Populations

HLA Database Breakdowns

Summary

To summarise HLA data stored in the Allele Frequency Net Database we have classified alleles grouped by Locus. Most frequently alleles are listed on the right side.
   

HLA Alleles


Locus Alleles
(IMGT/HLA)
 HLA-A 3,094
 HLA-B 3,866
 HLA-C 2,618
 HLA-DMA 7
 HLA-DMB 13
 HLA-DOA 12
 HLA-DOB 13
 HLA-DPA1 39
 HLA-DPB1 520
 HLA-DQA1 54
 HLA-DQB1 777
 HLA-DRA 7
 HLA-DRB1 1,719
 HLA-DRB2 1
 HLA-DRB3 59
 HLA-DRB4 15
 HLA-DRB5 21
 HLA-DRB6 3
 HLA-DRB7 2
 HLA-DRB8 1
 HLA-DRB9 1
 HLA-E 17
 HLA-F 22
 HLA-G 50
 HLA-H 12
 HLA-J 9
 HLA-K 6
 HLA-L 5
 HLA-P 5
 HLA-V 3
 HLA-Y 3
Total 12,974




          



          
 

Top HLA Allele Entries


Allele Total Entries
 HLA-DRB1*03:01 524
 HLA-DQB1*03:01 519
 HLA-DQB1*03:02 515
 HLA-DRB1*01:01 479
 HLA-DRB1*13:01 475
 HLA-DRB1*15:01 473
 HLA-DRB1*04:03 467
 HLA-DRB1*11:01 463
 HLA-DRB1*04:04 462
 HLA-DRB1*10:01 460
 HLA-DRB1*07:01 459
 HLA-B*35 452
 HLA-DRB1*14:01 451
 HLA-DRB1*13:02 450
 HLA-B*51 449
 HLA-B*07 445
 HLA-A*24 442
 HLA-B*44 442
 HLA-A*02 440
 HLA-DRB1*12:01 435
 HLA-A*33 433
 HLA-A*03 433
 HLA-DRB1*07 431
 HLA-B*39 431
 HLA-B*27 428
 HLA-B*13 426
 HLA-A*11 426
 HLA-DRB1*04:05 423
 HLA-B*18 421
 HLA-A*01 421

 


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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