Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 286 time(s) and present in 154 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CMRCameroon Bamileke 20.057035See
COLColombia San Basilio de Palenque0.048042See
ROMRomania pop 20.04006936See
USAUSA NMDP Black South or Central American0.03514889See
GHAGhana Accre Asutuare Akan0.0330429See
USAUSA OPTN African American0.03101510See
TTOTrinidad African0.030067See
CMRCameroon Ewondo0.026038See
MEXMexico Veracruz Xalapa4.80.023884See
CMRCameroon Podokwo0.023043See
MEXMexico Chihuahua Chihuahua City Pop 24.50.022788See
BRABrazil Parana Afro Brazilian3.90.019077See
MEXMexico Mexico City Tlalpan3.00.0152330See
BRABrazil Parana Oriental3.00.015033See
CHNChina Shandong Province Linqu County2.90.0146139See
CMRCameroon Uldeme0.014035See
BRABrazil REDOME Bahia0.013147399See
MEXMexico Morelos, Cuernavaca0.012282See
MEXMexico Mexico City Mestizo pop 30.0120256See
ZAFSouth Africa Tswana2.40.012041See
BRABrazil Parana Mixed race2.10.0110186See
CUBCuba Mixed pop 20.0110189See
MEXMexico Campeche Rural0.010647See
IRQIraq Arabs2.00.0101149See
MNGMongolia Khalkha pop 20.0100202See
MEXMexico Zacatecas, Fresnillo0.0095103See
MEXMexico Sinaloa Mestizo0.009056See
BRABrazil Rio Grande do Sul Mixed0.0090324See
MEXMexico Veracruz, Cordoba0.008956See
BRABrazil REDOME Piaui0.008446140See
MEXMexico Colima, Colima city0.008261See
MEXMexico Sinaloa Rural0.0082183See
BRABrazil Piaui Mixed0.008021943See
BRABrazil Rio Grande do Sul Black0.0080248See
COLColombia Barranquilla0.0080188See
CUBCuba Mixed0.008078See
BRABrazil REDOME Sergipe0.00797321See
MEXMexico Nayarit Rural0.007864See
MEXMexico Yucatan Rural0.0075132See
BRABrazil REDOME Maranhao0.007410180See
BRABrazil REDOME Rio de Janeiro0.0073139322See
BRABrazil Minas Gerais State Mixed1.40.00701000See
BRABrazil REDOME Minas Gerais0.0070211275See
ESPSpain Arratia Valley Basque0.007083See
MEXMexico Tapachula, Chiapas Mestizo Population1.40.006972See
BRABrazil REDOME Espirito Santo0.006688485See
BRABrazil REDOME Tocantins0.006620692See
MEXMexico Mexico City Center0.0065152See
BRABrazil REDOME Acre0.0064859See
BRABrazil REDOME Alagoas0.006225349See
BRABrazil South East Cord Blood0.005911409See
BRABrazil REDOME Rio Grande do Norte0.005946603See
BRABrazil REDOME Pernambuco0.005792332See
BRABrazil REDOME Rondonia0.005654396See
BRABrazil REDOME Goias0.005488574See
BRABrazil Para Cord Blood Unit0.00.0054841See
MEXMexico Aguascalientes state0.005395See
BRABrazil REDOME Ceara0.0051101217See
BRABrazil REDOME Mato Grosso0.005134649See
BRABrazil REDOME Mato Grosso do Sul0.005095667See
BRABrazil REDOME Sao Paulo0.0050800809See
BRABrazil REDOME Federal District0.005029549See
BRABrazil Rio Grande do Norte Mestizo0.005012973See
BRABrazil Sao Paulo Mixed0.10.0050239See
BRABrazil Pernambuco Mixed0.0050101See
ESPSpain Andalusia0.005099See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.005096See
BRABrazil REDOME Paraiba0.004943868See
BRABrazil Paraná Caucasian0.90.0047641See
BRABrazil REDOME Roraima0.00464140See
MEXMexico Coahuila Rural0.0046216See
BRABrazil Para State0.40.00435000See
ECUEcuador Coast Mixed Ancestry0.0042238See
ALBAlbanian Kosovo0.0042120See
BRABrazil REDOME Para0.004272637See
AREUnited Arab Emirates pop 20.80.0040373See
BRABrazil Sao Paulo Bauru Mixed0.00403542See
MEXMexico Mexico City Mestizo0.0040121See
USAUSA OPTN Hispanic0.00401580See
TURTurkey pop 50.0040142See
GTMGuatemala, Guatemala City Mixed Ancestry0.80.0039127See
BRABrazil REDOME Amapa0.003917864See
BRABrazil REDOME Amazonas0.003824129See
BRABrazil REDOME Parana0.0034341639See
CHESwitzerland Sion0.0032832See
CHNChina Harbin Manchu0.0030172See
BRABrazil Rio Grande do Sul Caucasoid0.00304428See
ARGArgentina Corrientes0.60.0030155See
BGDBangladesh Dhaka Bangalee0.0030141See
PERPeru Arequipa Mestizo0.70.0030168See
PRTMadeira pop 20.0030173See
BRABrazil REDOME Rio Grande do Sul0.0029241329See
MEXMexico Veracruz, Xalapa0.0027187See
MEXMexico Coahuila, Torreon0.0025396See
ALBAlbania pop 20.50.0023432See
CHESwitzerland Graubunden0.0022759See
ECUEcuador Mixed Ancestry0.00211173See
MEXMexico Oaxaca Rural0.0021485See
PRTPortugal Beja0.0020699See
PRTPortugal Portalegre0.00201254See
PRTPortugal Bragança0.0020301See
PRTPortugal Coimbra0.00205057See
USAUSA OPTN Asian0.0020261See
BRABrazil Parana Caucasian0.40.00202775See
BRABrazil Parana Cafuzo0.30.0020319See
BRABrazil REDOME Santa Catarina0.0019106673See
MEXMexico Mestizo pop 40.0019269See
MEXMexico Zacatecas Rural0.0019266See
MEXMexico Veracruz Rural0.0018539See
ITAItaly North Pavia pop 30.0017685See
ENGEngland North West Mixed pop 20.30.0013379See
MEXMexico Mexico City North0.0013751See
MEXMexico Jalisco, Guadalajara city0.00131189See
ECUEcuador Andes Mixed Ancestry0.0012824See
MEXMexico Puebla Rural0.0012833See
ITAItaly North Pavia pop 20.10.00102416See
ITAItaly Lombardy0.20.0010674See
ARGArgentina Cuyo Region0.20.0010420See
WALWales pop 20.00.001039979See
PRTPortugal Guarda0.0010797See
SAUSaudi Arabia pop 40.20.0010499See
PRTPortugal Porto0.00107937See
PRTPortugal Santarem0.00103865See
PRTPortugal Setubal0.00105268See
RUSRussia Northwest0.20.00101011See
PRTPortugal Braga0.00101971See
PRTPortugal Viana do Castelo0.0010706See
PRTPortugal Viseu0.00102915See
PRTPortugal Leiria0.00101847See
PRTPortugal Lisbon0.001017420See
PRTPortugal Aveiro0.00105933See
PRTPortugal Center pop 20.0010562See
PRTPortugal South pop 20.00101021See
MEXMexico Jalisco Rural0.0009585See
INDIndia North pop 30.0009587See
MEXMexico Tlaxcala Rural0.0006830See
GRCGreece pop 70.000611250See
FRAFrance Marseille0.10.00051000See
FRAFrance Bordeaux0.10.0005990See
FRAFrance Grenoble0.10.00051000See
ITAItaly South Campania Region0.10.00051089See
ESPSpain, Castilla y Leon, Northwest,0.10.00031743See
ISRIsrael Jews pop 20.10.000323000See
MEXMexico Puebla, Puebla city0.00031994See
IRLIreland South pop 20.000117624See
FRAFrance Lyon0.00.00014813See
HRVCroatia pop 20.0000100See
GRCGreece North0.0000500See
FRAFrance Southeast0.00.0000130See
FRAFrance Rennes pop 30.0000200See
ESPSpain Majorca0.0000407See
ESPSpain Minorca0.000094See
ESPSpain Ibiza0.000088See
ESPSpain Majorcans Jews0.0000103See
ESPSpain Murcia0.0000173See
ECUEcuador Amazonia Mixed Ancestry0.000039See
ENGEngland Sheffield0.00.00004755See
ENGEngland Leeds0.00.00005024See
ENGEngland Newcastle0.00.00002739See
CUBCuba Mixed Race0.00.000042See
IRNIran Royan Cord Blood Bank0.00.000015600See
ISRIsrael Moroccan Jews0.0000113See
ISRIsrael Ashkenazi Jews pop 20.0000132See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
JPNJapan Hyogo Osaka and Nagano0.0000195See
KORSouth Korea pop 10.0000324See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Casablanca0.0000100See
MARMorocco pop 20.0000110See
MEXMexico Mestizo0.00.000041See
MEXMexico Huasteca Region Teenek0.000055See
MEXMexico Puebla Mestizo0.000099See
MEXMexico Morelos Rural0.000030See
MEXMexico Tabasco Rural0.0000142See
MEXMexico Chiapas Rural0.0000121See
MEXMexico Hidalgo Rural0.000081See
MEXMexico Mexico City Metropolitan Area Rural0.0000150See
MEXMexico Baja California, Tijuana0.000025See
MEXMexico Quintana Roo Rural0.000050See
AUSAustralia West Caucasian0.00.0000891See
BIHBosnia and Herzegovina0.0000134See
ARGArgentina Buenos Aires pop 20.10.00001216See
ARGArgentina La Plata0.00.0000100See
ARGArgentina Rosario Toba0.00.000086See
ARGArgentina Chiriguano0.00.000054See
ARGArgentina Salta Wichi pop 20.00.000019See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
CHNChina Harbin Korean0.0000201See
CHNChina North Han0.0000105See
CHNChina Shanghai0.000026266See
CHNChina Shandong Province0.00.00007418See
CHESwitzerland Zurich0.00004875See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Mexico City South0.000052See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Mexico City West0.000033See
MEXMexico Yucatan, Merida0.0000192See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Tabasco, Villahermosa0.000082See
MKDMacedonia pop 40.0000216See
MNGMongolia Hoton0.000085See
MEXMexico Veracruz, Veracruz city0.0000171See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Oaxaca, Oaxaca city0.0000151See
MEXMexico Guerrero state0.0000144See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Mexico City East0.000079See
MEXMexico Nuevo Leon, Monterrey city0.0000226See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Michoacan Rural0.0000348See
MEXMexico Baja Californa, Mexicali0.0000100See
MEXMexico Baja California Rural0.000050See
MEXMexico Sonora Rural0.0000197See
MEXMexico Guanajuato Rural0.0000162See
MEXMexico Colima Rural0.000043See
MEXMexico Nuevo Leon Rural0.0000439See
MEXMexico Queretaro Rural0.000043See
MEXMexico Tamaulipas Rural0.0000125See
MEXMexico San Luis Potosi Rural0.000087See
MEXMexico Durango Rural0.0000326See
MEXMexico Coahuila, Saltillo0.000072See
MEXMexico Durango, Durango city0.0000153See
MEXMexico Michoacan, Morelia0.0000150See
MEXMexico Jalisco, Zapopan0.0000168See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Chihuahua Rural0.0000236See
MEXMexico Chihuahua, Ciudad Juarez0.0000106See
MEXMexico Chihuahua Chihuahua City0.0000119See
MEXMexico Sinaloa, Culiacán0.0000103See
MEXMexico Sonora, Hermosillo0.000099See
MEXMexico Sonora, Ciudad Obregón0.0000143See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Nayarit, Tepic0.000097See
MYSMalaysia pop 20.000062See
PAKPakistan Burusho0.000092See
PAKPakistan Mixed Sindhi0.0000101See
PRTMadeira pop 30.0000538See
PRTPortugal Vila Real0.00001167See
RUSRussia Moscow0.00002650See
RUSRussia South Ural Russian0.00.0000207See
RUSRussia South Ural Bashkir0.00.0000146See
RUSRussia South Ural Tatar0.00.0000135See
RUSRussia Northwest pop 30.00.0000100See
SAUSaudi Arabia pop 20.0000383See
RUSRussia Nenet Mixed0.000055See
RUSRussia Arkhangelsk Pomor0.000063See
RUSRussia Murmansk Saomi Mixed0.000070See
PRTPortugal Evora0.0000737See
PRTPortugal Faro0.00001242See
PRTPortugal Castelo Branco0.0000327See
SVNSlovenia pop 30.00.0000130See
THAThailand pop 40.000016807See
TTOTrinidad South Asian0.000087See
USAUSA South Texas Hispanic0.0000194See
ZAFSouth Africa Natal Zulu0.00.0000100See
USAUSA OPTN Caucasian0.00008525See

See also higher resolution data of this allele

Allele  Number of Populations 
 A*36:01 172 
 A*36:02 26 
 A*36:03 31 
 A*36:04 25 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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