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KIR » Linkage disequilibrium in KIR genes


 KIR gene organisation

The figures shown below present a summary of relationships between KIR genes, which are organised by centromeric (blue) and telomeric (pink) content. The aim of these figure is to describe the strongest linkage (values from 0-100%) among the different KIR genes. Gene association values are estimated usin the genotype list which is available on the website.

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Total individuals analysed: 24952

 


Overall linkage


 
 CentromericTelomeric
 
 3DL3 46904753289697981009340364192100
  2DS2 3796687243434546445658584546
   2DL3 38472692919090864136418590
    2DL2 697244444647455659584647
     2DL5 7253525253478179834753
      2DS3 30292828286656633028
       2DL1 979596914036419096
        2DP1 9797913935409097
         3DP1 98923935409198
          2DL4 9340364192100
           3DL1 3431359693
            3DS1 83913440
             2DS5 863136
              2DS1 3641
               2DS4 92
                3DL2 




Both genes positive


 
 CentromericTelomeric
 3DL3 46904753289697981009340364192100
  2DS2 3744342343434546422120234146
   2DL3 38452289898990853531368390
    2DL2 352344444647432121234247
     2DL5 2751515253473734394653
      2DS3 27272828251710162528
       2DL1 959596903834398996
        2DP1 9697913834398997
         3DP1 98923935409198
          2DL4 9340364192100
           3DL1 3430359193
            3DS1 29363340
             2DS5 322936
              2DS1 3441
               2DS4 92
                3DL2 




Both genes negative



 
 CentromericTelomeric
 3DL3 000000000000000
  2DS2 15135491000235383630
   2DL3 0243200165520
    2DL2 34481000234383530
     2DL5 451100044454410
      2DS3 3200349464750
       2DL1 200122210
        2DP1 00011110
         3DP1 0000000
          2DL4 000000
           3DL1 01060
            3DS1 545510
             2DS5 5520
              2DS1 10
               2DS4 0
                3DL2 

   

Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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