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Notes:

¹ Epitope frequencies were calculated using raw genotyping data.
² Epitope frequencies were calculated using haplotype frequencies.

Line	Population	AA Position	Loci	Epitope	Epitope Frequency (in_decimals)	Sample Size	Location
1	Azores Central Islands¹	44, 45, 46	B	44RT	0.5200	56	38_0_N_28_0_W
2	Azores Oriental Islands¹	44, 45, 46	B	44RT	0.5600	39	36_58_N_25_6_W
3	Cape Verde Northwestern Islands¹	44, 45, 46	B	44RT	0.8100	62	16_0_N_24_0_W
4	Cape Verde Southeastern Islands¹	44, 45, 46	B	44RT	0.5600	62	16_0_N_24_0_W
5	England North West¹	44, 45, 46	B	44RT	0.3300	298	53_0_N_3_0_W
6	Ghana Ga-Adangbe¹	44, 45, 46	B	44RT	0.7000	131	5_45_N_0_12_E
7	Guinea Bissau¹	44, 45, 46	B	44RT	0.6600	65	12_0_N_15_0_W
8	Ireland Northern¹	44, 45, 46	B	44RT	0.2700	1,000	54_40_N_6_45_W
9	Ireland South¹	44, 45, 46	B	44RT	0.2700	250	53_20_N_6_15_W
10	Madeira¹	44, 45, 46	B	44RT	0.5400	185	32_44_N_16_58_W
11	Mexico City Mestizo pop 2²	44, 45, 46	B	44RT	0.5700	234	19_26_N_99_8_W
12	Mexico Oaxaca Mixe²	44, 45, 46	B	44RT	0.6900	55	17_5_N_96_45_W
13	Mexico Oaxaca Mixtec²	44, 45, 46	B	44RT	0.7800	103	17_5_N_96_45_W
14	Philippines Ivatan²	44, 45, 46	B	44RT	0.2400	50	20_22_N_121_56_E
15	Poland DKMS²	44, 45, 46	B	44RT	0.4600	20,653	52_8_N_19_23_E
16	Portugal Center¹	44, 45, 46	B	44RT	0.6600	50	39_0_N_8_0_W
17	Portugal North¹	44, 45, 46	B	44RT	0.5200	46	41_0_N_8_0_W
18	Portugal South¹	44, 45, 46	B	44RT	0.6900	49	37_0_N_8_0_W
19	Sao Tome Island Angolar¹	44, 45, 46	B	44RT	0.9200	12	0_20_N_6_44_E
20	Sao Tome Island Forro¹	44, 45, 46	B	44RT	0.7800	50	0_20_N_6_44_E
21	Saudi Arabia pop 5¹	44, 45, 46	B	44RT	0.5600	158	24_38_N_46_43_E
22	Taiwan Ami²	44, 45, 46	B	44RT	0.0000	98	23_0_N_121_0_E
23	Taiwan Bunun²	44, 45, 46	B	44RT	0.0000	101	23_46_N_121_0_E
24	Taiwan Puyuma²	44, 45, 46	B	44RT	0.0000	50	23_0_N_121_0_E
25	Taiwan Rukai²	44, 45, 46	B	44RT	0.0000	50	23_0_N_121_0_E
26	Taiwan Tao²	44, 45, 46	B	44RT	0.0000	50	24_0_N_121_0_E
27	Taiwan Thao²	44, 45, 46	B	44RT	0.1000	30	24_0_N_121_0_E
28	USA African American pop 4²	44, 45, 46	B	44RT	0.5700	2,411	44_58_N_93_15_W
29	USA African American pop 4²	44, 45, 46	B	44RT	0.5800	2,411	44_58_N_93_15_W
30	USA Asian pop 2²	44, 45, 46	B	44RT	0.4700	1,772	44_58_N_93_15_W
31	USA Asian pop 2²	44, 45, 46	B	44RT	0.4800	1,772	44_58_N_93_15_W
32	USA Hispanic pop 2²	44, 45, 46	B	44RT	0.5400	1,999	44_58_N_93_15_W
33	USA Hispanic pop 2²	44, 45, 46	B	44RT	0.5500	1,999	44_58_N_93_15_W

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Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
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